Injection-Site Sarcoma in a Dog: Clinical and Pathological Findings
2017 ◽
Vol 2017
◽
pp. 1-4
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Keyword(s):
This case report documents the clinical and pathological findings in a dog that rapidly developed a high-grade sarcoma at the site of multiple vaccinations and follows the response to surgery and adjunct treatment with toceranib. An 11-year-old female spayed Labrador Retriever presented with dorsocervical subcutaneous masses at the injection site three weeks after receiving DA2PP-Lepto, Rabies, and Bordetella vaccinations. A high-grade soft tissue sarcoma was diagnosed microscopically and immunohistochemistry revealed positive expression of VEGFr, PDGFr, SCF, and EGFR. Repeat surgical resections and targeted treatment with toceranib resulted in a stable remission for nearly two years.
2012 ◽
Vol 70
(9)
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pp. 2211-2217
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Keyword(s):
2009 ◽
Vol 6
(1)
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Keyword(s):
1988 ◽
pp. 115-122
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Keyword(s):
Keyword(s):
2019 ◽
Vol 105
(1)
◽
pp. E805