scholarly journals High-grade soft tissue sarcoma arising in a desmoid tumor: case report and review of the literature

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
François Bertucci ◽  
Marjorie Faure ◽  
Maria-Rosa Ghigna ◽  
Bruno Chetaille ◽  
Jérôme Guiramand ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Terry M. Jacobs ◽  
Cathy E. Poehlmann ◽  
Matti Kiupel

This case report documents the clinical and pathological findings in a dog that rapidly developed a high-grade sarcoma at the site of multiple vaccinations and follows the response to surgery and adjunct treatment with toceranib. An 11-year-old female spayed Labrador Retriever presented with dorsocervical subcutaneous masses at the injection site three weeks after receiving DA2PP-Lepto, Rabies, and Bordetella vaccinations. A high-grade soft tissue sarcoma was diagnosed microscopically and immunohistochemistry revealed positive expression of VEGFr, PDGFr, SCF, and EGFR. Repeat surgical resections and targeted treatment with toceranib resulted in a stable remission for nearly two years.


Sarcoma ◽  
2007 ◽  
Vol 2007 ◽  
pp. 1-4 ◽  
Author(s):  
Brian Boulmay ◽  
Gary Cooper ◽  
John D. Reith ◽  
Robert Marsh

Synovial sarcoma comprises approximately 10%of all soft tissue sarcoma diagnoses; a primary synovial sarcoma of the myocardium is exceedingly rare. There have been very few cases reported in the literature thus far. With the identification of the characteristic and diagnostic chromosomal abnormality t(X;18), this may become an increasingly recognized entity. Our report adds to the limited published cases of primary cardiac synovial sarcoma with the characteristic t(X;18). Further elucidation of the effects of this translocation on the cell cycle may lead to directed therapies in the future.


Sarcoma ◽  
2006 ◽  
Vol 2006 ◽  
pp. 1-3 ◽  
Author(s):  
Michelle Ferguson ◽  
William Stewart ◽  
Fiona Cowie ◽  
Jeff White

Intracranial metastases from liposarcoma are rare and almost always preceded by the development of systemic tumour spread. We report here a case of liposarcoma with spread to the cranial nervous system 23 years after treatment of the primary tumour. The literature on brain metastases from soft tissue sarcoma is also reviewed.


2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Abhinav Tiwari ◽  
Bhavana Siddegowda Bangalore ◽  
Himani Sharma ◽  
Zaid Ammari ◽  
Mohammad S. Khan ◽  
...  

Alveolar soft part sarcoma is a very uncommon soft tissue malignancy which accounts for <1% of soft tissue sarcoma. It is a malignant and highly vascular tumor arising most commonly in the musculature of the lower extremities, with metastasis primarily to the lungs, bones, and brain. Cardiac metastasis is very rare and only 5 cases have been reported in the literature so far. We report a case of a young woman with a history of surgically resected alveolar soft part sarcoma of left thigh who presented with persistent dry cough and was found to have a cardiac mass, which on biopsy proved to be alveolar soft part sarcoma.


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