scholarly journals Two Cases of Catastrophic AAA Rupture in Young Women with Systemic Lupus Erythematosus

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
David Noorvash ◽  
Kevin King ◽  
Meera Gebrael
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Emergency Department ◽  
Abdominal Aortic Aneurysm ◽  
Young Women ◽  
Lupus Erythematosus ◽  
Relevant Literature ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Past Medical History ◽  
Systemic Lupus ◽  
Abdominal Aortic

We present two cases of young women with a past medical history significant for systemic lupus erythematosus (SLE), who presented to the Emergency Department with a ruptured abdominal aortic aneurysm (AAA). These cases are of particular interest because the patients did not fit the typical demographic for patients who present with a ruptured AAA. Based on these cases and a review of the relevant literature, ED providers should maintain a higher index of suspicion for AAA rupture in patients with autoimmune diseases, especially SLE.

scholarly journals Surgical treatment of recurrent abdominal aortic aneurysm in a patient with systemic lupus erythematosus

2000 ◽  
Vol 32 (1) ◽  
pp. 209-212 ◽  
Author(s):  
Naoki Washiyama ◽  
Teruhisa Kazui ◽  
Makoto Takinami ◽  
Katsushi Yamashita ◽  
Hitoshi Terada ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Abdominal Aortic Aneurysm ◽  
Surgical Treatment ◽  
Aortic Aneurysm ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Abdominal Aortic

scholarly journals A Case of Abdominal Aortic Aneurysm in a Systemic Lupus Erythematosus Patient.

1999 ◽  
Vol 28 (3) ◽  
pp. 201-204
Author(s):  
Hitoshi Matsumoto ◽  
Toshiyuki Yuda ◽  
Takayuki Ueno ◽  
Yousuke Hisashi ◽  
Yukinori Moriyama ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Systemic Lupus Erythematosus Patient ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Abdominal Aortic

Ruptured Mycotic Abdominal Aortic Aneurysm in a Patient with Systemic Lupus Erythematosus

1998 ◽  
Vol 4 (1) ◽  
pp. 36-38
Author(s):  
Worawit Louthrenoo ◽  
Wannee Ojarasporn ◽  
Angkana Norasetthada ◽  
Waraporn Sukitawut
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Abdominal Aortic

scholarly journals A Case of Abdominal Aortic Aneurysm Associated with Systemic Lupus Erythematosus.

1994 ◽  
Vol 23 (3) ◽  
pp. 217-220 ◽  
Author(s):  
Toshihiko Shibata ◽  
Tadashi Yamada ◽  
Kanji Ishihara ◽  
Norio Suzuki ◽  
Masataka Eirai ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Abdominal Aortic

scholarly journals Mycotic Abdominal Aortic Aneurysm in a Patient With Systemic Lupus Erythematosus: A Case of Critical Antinomy

2021 ◽  
Author(s):  
Kensuke Kobayashi ◽  
Nobuyuki Inoue ◽  
Takuma Fukunishi
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Lupus Erythematosus ◽  
Aortic Aneurysms ◽  
Systemic Lupus ◽  
Spinal Fusion Surgery ◽  
Abdominal Aortic ◽  
Life Threatening ◽  
Thorough Debridement

Abstract Mycotic abdominal aortic aneurysms are rare but life-threatening, and no standard therapy has yet been established. Effective surgery with intensive antimicrobial therapy is crucial; however, this can be fatal in immunocompromised patients. Only a few reports of mycotic abdominal aortic aneurysm with concomitant autoimmune disease exist; therefore, we were concerned about our lack of experience and knowledge about appropriate treatment. We report a 69-year-old male with a mycotic abdominal aortic aneurysm secondary to septic shock after spinal fusion surgery. He had also been on long-term oral immunosuppressants for systemic lupus erythematosus. After preoperative cephazolin, we performed debridement of infected tissue, graft replacement with a rifampicin-bonded prosthesis, and omentopexy. On the 52nd postoperative day, he was transferred back to the previous attending hospital under oral antibiotics and prednisolone. Mycotic abdominal aortic aneurysm in patients with systemic lupus erythematosus should be treated with in situ replacement using an antimicrobial prosthetic or biological graft with thorough debridement and omentopexy, followed by antimicrobials and immunosuppressants, as needed.

Myocardial Infarction in Systemic Lupus Erythematosus – the Sex Specific Risk Profile

2020 ◽  
Vol 26 ◽  
Author(s):  
Marija Vavlukis ◽  
Daniela Pop-Gjorceva ◽  
Lidija Poposka ◽  
Emilija Sandevska ◽  
Sasko Kedev
Keyword(s):  
Myocardial Infarction ◽  
Systemic Lupus Erythematosus ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Young Women ◽  
Lupus Erythematosus ◽  
Molecular Mechanisms ◽  
Clinical Presentation ◽  
Systemic Lupus ◽  
Antiinflammatory Therapy

Background: Accelerated atherosclerosis is widely present in patients with systemic lupus erythematosus. Objective: The aim of this review is to analyze the relationship between systemic lupus erythematosus and cardiovascular diseases, with the emphasis on acute myocardial infarction. Results: Various molecular mechanisms triggered by infection/inflammation are responsible for endothelial dysfunction and development of atherosclerosis at an earlier age. Contributing factor is the cumulative effect of traditional cardiovascular risk factors interaction with disease related characteristics. Myocardial infarction rates are 2- to 10-fold higher compared to the general population. Young women have the highest relative risk, however, men carry at least 3- fold higher risk than women. Coronary involvement varies from normal coronary artery with thrombosis, coronary microartery vasculitis, coronary arteritis, and coronary atherosclerosis. Typical clinical presentation is observed in men and older women, while atypical is more frequent in young women. Treatment is guided by the underlying mechanism, engaging invasive procedures alone, or accompanied with immunosuppressive and/or antiinflammatory therapy. There are significant gender differences in pathophysiology and clinical presentation. However, they receive the same therapeutic treatments. Conclusion: Systemic lupus erythematosus is a major contributor to atherosclerotic and non-atherosclerotic mechanisms involved in the development of myocardial infarction, which should be taken into account during therapeutic treatment. Although Systemic lupus erythematosus per se is a “female” disease, males are at increased cardiovascular risk and worse outcome. Method: We conducted a literature review through PubMed and Cochrane, using key words: SLE, atherosclerosis, atherothrombosis, coronary artery disease, myocardial infarction, prognosis, sex specifics.

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