scholarly journals A Rare Malignant Transformation of an Ovarian Cystic Teratoma: A Case Report

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Manju Rachel Mathew ◽  
Anita Ramdas ◽  
Susy S. Kurian ◽  
Linu Kuruvilla ◽  
Neelima Singh
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Germ Cell ◽  
Urothelial Carcinoma ◽  
Malignant Transformation ◽  
Histopathological Examination ◽  
Cystic Teratoma ◽  
Rare Occurrence ◽  
Urothelial Carcinomas ◽  
Cell Neoplasm

Mature cystic teratoma (MCT) is the commonest germ cell neoplasm of the ovary but malignant transformation is a rare occurrence (1-2%). Of these malignancies documented in literature the commonest are squamous cell carcinoma and adenocarcinoma. Urothelial carcinomas arising in an MCT are a rare occurrence and only 7 cases have been reported in literature. We report a case of an MCT which was complicated by the presence of urothelial carcinoma confirmed on histopathological examination.

scholarly journals Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary: A Case Report with Review of Literature

2011 ◽  
Vol 3 (3) ◽  
pp. 135-137
Author(s):  
R Kalyani ◽  
BN Gayathri ◽  
K Vidyavathi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Germ Cells ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Secondary Development ◽  
Review Of Literature ◽  
Ovarian Masses

ABSTRACT Up to a quarter of ovarian masses originate from germ cells and many of these are mature cystic teratomas (MCT). The secondary development of malignancy is a rare but well-known phenomenon in patient with ovarian teratomas. The incidence of malignant transformation in mature cystic teratoma of the ovary is less than 2% as reported in gynecological and pathological literature. Here, we present a case of malignant transformation in MCT of the ovary.

scholarly journals Seborrheic keratosis evolution into squamous cell carcinoma: A truly modified sun-related tumor? A case report and review of the literature

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Ioana Cimpean ◽  
Ivan Theate ◽  
Olivier Vanhooteghem
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Malignant Transformation ◽  
Histopathological Examination ◽  
Clinical Manifestations ◽  
Immunocompromised Patients ◽  
Review Of The Literature ◽  
Seborrheic Keratosis ◽  
Increased Risk

The incidence of seborrheic keratosis (SK) generally increases with age and are mostly localized on the trunk, face and neck, especially on sun-exposed areas. The association between SK and skin malignancies appears to be accidental, but in situ transformation occurs more frequently in sun-exposed areas. Histopathological examination of all SK cases should be considered, especially when SK lesions exhibit atypical clinical manifestations, such as ulceration and cresting, as they may herald malignant transformation. In addition, other features associated with malignant transformation include excoriations or hemorrhages identified on the lesion, modification and evolution of the macroscopic characteristics, and the presence of local erythema or pruritus. Immunocompromised patients exhibit an increased risk of malignant transformation, even when radiation is involved.

scholarly journals Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: A case report and review of literature

2021 ◽  
Author(s):  
Namkha Dorji ◽  
Sangay Tshering ◽  
Sonam Choden
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Rare Complication ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Review Of Literature ◽  
Thickened Wall

Introduction: Malignant transformation in mature cystic teratoma of ovary is a rare complication. Case report: A 62-year-old woman was diagnosed with squamous cell carcinoma in a mature cystic teratoma of ovary. Conclusion: Malignant transformation should be suspected in elderly woman with large mature cystic teratoma of ovary with thickened wall.

scholarly journals Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary

2014 ◽  
Vol 9 (1) ◽  
pp. 61-63
Author(s):  
N Gupta ◽  
T Gupta ◽  
S Jindal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Germ Cell ◽  
Cell Carcinoma ◽  
Postmenopausal Women ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Squamous Epithelium ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma

Malignant transformation of mature germ cell teratoma is rare and has been reported sporadically. Any of the constituent tissue of a teratoma has the potential to undergo malignant transformation. Squamous cell carcinoma is the most common transformation and is derived from the metaplastic squamous epithelium of teratoma. We are reporting a case of 65 years old postmenopausal women with squamous cell carcinoma arising in mature cystic cell teratoma of the ovary. DOI: http://dx.doi.org/10.3126/njog.v9i1.11191 NJOG 2014 Jan-Jun; 2(1):61-63

scholarly journals A rare case of urothelial carcinoma arising in mature cystic teratoma

2018 ◽  
Vol 7 (7) ◽  
pp. 2959
Author(s):  
Nitesh R. Maurya ◽  
Urvi C. Bhavsar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urothelial Carcinoma ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Post Menopausal ◽  
Common Malignancy ◽  
Adnexal Tumour

Mature cystic teratoma is a common benign adnexal tumour in females. It is composed of all the three germ layers (mesoderm, endoderm and ectoderm). Malignant transformation in a mature cystic teratoma of the ovary is rare, occurring in only 1-2% of cases. The most common malignancy is squamous cell carcinoma, which consists of about 80% of malignant transformations. Here we report malignant transformation of MCT in a 74year old post-menopausal female. Grossly the ovary was large cystic occupying the entire abdomen. Trial dissection was done and only 50% of the mass could be dissected due to gross adhesions. HPE reported as urothelial carcinoma in mature cystic teratoma. MCT is easily diagnosed via sonography, but malignant transformation is difficult to identify before surgery. For patients with malignant transformation, squamous cell carcinoma is the most common malignancy arising from MCT, and accounts for 80% of all cases. Other malignancies, such as adenocarcinomas, sarcomas or malignant melanomas have been reported; however, urothelial carcinoma arising from MCT is rare.

OVARIAN MATURE CYSTIC TERATOMA WITH TRANSFORMATION INTO SQUAMOUS CELL CARCINOMA: REPORT OF TWO CASES

2021 ◽  
pp. 38-39
Author(s):  
Supriya Pradhan ◽  
Bhuvan Adhlakha ◽  
Vijay D Dombale
Keyword(s):  
Squamous Cell Carcinoma ◽  
Germ Cell ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Germ Cell Tumors ◽  
Rare Event ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma

Ovarian mature cystic teratomas are the commonest germ cell tumors of the ovary. Malignant transformation in them is a rare event and is difcult to diagnose preoperatively. Clinicians, pathologists and radiologists should always suspect this if the patient is elderly or when the cyst is large or in presence of a solid foci. Here, we discuss two cases of squamous cell carcinoma arising from a mature cystic teratoma

scholarly journals Malignant Degeneration in a Mature Cystic Teratoma of Ovary A Case Report

2003 ◽  
Vol 40 (138) ◽  
pp. 90-92
Author(s):  
Mamata Lakhey ◽  
K Verma ◽  
I R Khan ◽  
S P Sah ◽  
S Rani
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Surgical Approach ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Malignant Degeneration ◽  
Benign Cystic Teratoma

Malignant transformation of benign cystic teratoma of ovary is rare and the mostcommon malignancy encountered is squamous cell carcinoma. The diagnosis is rarelymade preoperatively and the prognosis is usually poor. Here we report a case ofsquamous cell carcinoma arising in a dermoid in a 44 years old lady who presentedwith bilateral dermoid cysts. The preoperative findings, surgical approach andadjuvant therapy are discussed.Key Words: Malignant transformation, benign cystic teratoma, squamous cell carcinoma.

scholarly journals Malignant Transformation of Mature Cystic Teratoma into Undifferentiated Carcinoma: a case report.

2021 ◽  
Author(s):  
Vinayak Aryal ◽  
Rubina Maharjan ◽  
Moushami Singh ◽  
Adwait Marhatta ◽  
Anu Bajracharya ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Cystic Teratoma ◽  
Undifferentiated Carcinoma ◽  
Mature Cystic Teratoma ◽  
Rare Entity

Malignant transformation of mature cystic teratoma (MCTO) is a rare entity. Even rarer is the transformation of MCTO into undifferentiated carcinoma. We report a case of an 80-year-old woman with undifferentiated carcinoma and squamous cell carcinoma component originating from mature cystic teratoma of the ovary.

scholarly journals Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Shramana Mandal ◽  
Bhawana A. Badhe
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Malignant Melanoma ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Rare Complication ◽  
Mature Teratoma ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Sebaceous Tumor

Malignant transformation of a mature cystic teratoma (MCT) is a very rare complication with an incidence of 0.17–2%;. The most common form of malignant transformation of the MCT is squamous cell carcinoma. Other tumors arising in MCT include basal cell carcinoma, sebaceous tumor, malignant melanoma, adenocarcinoma, sarcoma, and neuroectodermal tumor. However malignant transformation with metastatic deposits in the omentum is extremely rare. The present case highlights the rarity of the occurrence of an omental deposits in a case of mature cystic teratoma with malignant transformation.

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