scholarly journals Modified Synthesis and Physicochemical Characterization of a Bioglass-Based Composite for Guided Bone Regeneration

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Marcos José da Silva ◽  
Wellington Alves ◽  
Carlos Frederico de Oliveira Graeff ◽  
Paulo Henrique Perlatti D’Alpino
Keyword(s):  
Porous Structure ◽  
Bone Graft ◽  
Bone Regeneration ◽  
Functional Groups ◽  
Compression Strength ◽  
Physicochemical Characterization ◽  
Guided Bone Regeneration ◽  
Morphological Properties ◽  
Ftir Analysis ◽  
Composite Surface

Objectives. Bioglass composites and polymers are materials of great interest for the medical and dental areas due to their properties, combining the bioactivity of ceramic materials and the mechanical properties of polymers. The purpose of the present study was to develop and to characterize the physicochemical and morphological properties an experimental bioglass-based ternary composite composed associated with sodium carboxymethylcellulose (Na-CMC) and polyvinyl alcohol (PVA). The compatibility of functional groups with bioglass was previously evaluated. The composite was then synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity. Materials and Methods. The bioglass was previously synthesized using a sol-gel route and characterized using FTIR analysis to identify the functional groups. The bone graft composite was then synthesized associating the bioglass with PVA, surfactant Triton X, and Na-CMC. The composite was then morphologically characterized using SEM/EDS. The porosity of the composite was analyzed using µCT, which also provided the composite compression strength. The composite was then evaluated in terms of its bioactivity using SEM/EDS analyses after immersion in SBF for 12, 24, 48, and 72 h. Results. FTIR analysis confirmed, among other components, the presence of Si–O–Ca and Si–O–Si bonds, compatible with bioglass. SEM analysis exhibited a composite with a porous structure without spikes. The elemental mapping confirmed the presence of Si, Ca, and P in the composite. µCT analysis demonstrated a porous structure with 42.67% of open pores and an average compression strength of 124.7 MPa. It has also demonstrated ionic changes in the composite surface after immersion in SBF, with increasing detection of Ca and P as a function of time, highlighting its chemical bioactivity. Conclusions. It can be concluded that the proposed bioglass-based composite presents a three-dimensional, well-structured, chemically bioactive porous structure, mechanically resistant for being reinforced with polymeric phases, with promising results as a synthetic bone graft, which makes it suitable for guided bone regeneration.

scholarly journals Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft

2015 ◽  
Vol 16 (2) ◽  
pp. 154-162 ◽  
Author(s):  
Danilo Alessio Di Stefano ◽  
Gian Battista Greco ◽  
Lorenzo Cinci ◽  
Laura Pieri
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Bone Sample ◽  
Successful Outcome ◽  
Autogenous Bone ◽  
Titanium Mesh ◽  
Ridge Augmentation ◽  
Stereolithographic Model ◽  
Equine Bone

ABSTRACT Aim The present work describes a horizontal ridge augmentation in which a titanium mesh was preshaped by adapting it to a stereolithographic model of the patient's jaw that was fabricated from CT scans. Background Guided bone regeneration (GBR) involves covering the augmentation site with a long-lasting barrier to protect it from the invasion of surrounding soft tissues. Among barriers, titanium meshes may provide a successful outcome, but the intraoperatory time needed to shape them is a disadvantage. Case description The 54-year-old patient, missing the right mandibular second bicuspid, first molar, and second molar, had her atrophic ridge augmented with a 30:70 mixture of autogenous bone and equine, enzyme-deantigenic collagenpreserved bone substitute. Two conical implants were inserted concomitantly in the second bicuspid and first molar positions, and the site was protected with the preshaped mesh. Four months later, the titanium mesh was retrieved, a bone sample was collected, and histological and histomorphometric analyses were performed. Provisional and definitive prostheses were then delivered, and follow-up controls were performed for up to 24 months. Conclusion Preshaping the mesh on a model of the patient's mandible shortened the surgical time and enabled faster mesh placement. Two years after surgery, the implants were perfectly functional, and the bone width was stable over time as shown by radiographic controls. Histological analysis of the bone sample showed the heterologous biomaterial to be biocompatible and undergoing advanced remodeling and replacement with newly formed bone. Clinical significance Preshaping a titanium mesh over a stereolithographic model of the patient's jaw allowed for a significant reduction of the intraoperative time and may be therefore, advisable in routine practice. How to cite this article Di Stefano DA, Greco GB, Cinci L, Pieri L. Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft. J Contemp Dent Pract 2015;16(2):154-162.

Guided Bone Regeneration of Femoral Segmental Defects using Equine Bone Graft: An In-Vivo Micro-Computed Tomographic Study in Rats

2018 ◽  
Vol 32 (5) ◽  
pp. 456-466 ◽  
Author(s):  
Mohammed Awadh Binsalah ◽  
Sundar Ramalingam ◽  
Mohammed Alkindi ◽  
Nasser Nooh ◽  
Khalid Al-Hezaimi
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Computed Tomographic ◽  
Equine Bone

Prefabrication of Vascularized Bone Graft Using Guided Bone Regeneration

2004 ◽  
Vol 10 (7-8) ◽  
pp. 978-986 ◽  
Author(s):  
Akishige Hokugo ◽  
Yoshinobu Kubo ◽  
Yoshitake Takahashi ◽  
Aoi Fukuda ◽  
Kaoru Horiuchi ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Vascularized Bone Graft ◽  
Vascularized Bone

Peri-Implantitis Associated With a Pre-Existing Pathology

2017 ◽  
Vol 43 (3) ◽  
pp. 232-236
Author(s):  
Se-Lim Oh
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Bone Graft ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Histopathologic Evaluation

This case report presents a treatment of peri-implantitis associated with a pre-existing pathology. Peri-implantitis around implant #19 was detected from pus discharge upon probing. Guided bone regeneration was performed to treat the peri-implantitis with the administration of antibiotics. The histopathologic evaluation of soft tissue taken from the circumferential defect around the implant exhibited a cyst. The postsurgical CBCT and the follow-up radiograph confirmed the maturing bone graft and a reduced size of the defect around the implant.

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