A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

In this report, we describe a patient with myoepithelial hamartoma, which is regarded as synonymous with adenomyosis and heterotopic pancreas. Endoscopy revealed a submucosal tumor in the antrum of the stomach. Subsequently, distal gastrectomy with Roux-en-Y reconstruction was performed. Histological findings of adenomyomatous lesion and heterotopic pancreatic tissue were observed in this lesion. The distribution of OCT4, which is a pluripotency marker, varied in each part.

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Heterotopic Pancreas as Lead Point in Intussusception: New Variant of Vitellointestinal Tract Malformation

Pediatric and Developmental Pathology ◽

10.1007/s100249900136 ◽

1999 ◽

Vol 2 (4) ◽

pp. 367-370 ◽

Cited By ~ 18

Author(s):

Robin Abel ◽

Charles E. Keen ◽

John B. Bingham ◽

John Maynard ◽

Meena R. Agrawal ◽

...

Keyword(s):

Small Intestine ◽

Meckel’S Diverticulum ◽

Pancreatic Tissue ◽

Heterotopic Pancreas ◽

Meckel's Diverticulum ◽

Ectopic Gastric Mucosa ◽

Lead Point ◽

Heterotopic Pancreatic Tissue ◽

New Variant ◽

Acinar Tissue

Two cases of intussusception are reported with heterotopic pancreatic tissue attached to and draining into the ileum. The first patient, a boy aged 16 months, presented with ileoileal intussusception. The diagnosis was confirmed on ultrasound scan. Laparotomy and resection were performed. A 12-mm nodule of heterotopic pancreatic tissue was identified in the ileal serosa at the apex of the intussusceptum, fully formed with acinar tissue, islets, and draining duct. The second patient, also a boy aged 16 months, presented with obstructed ileocolic intussusception in which the lead point at surgery resembled a Meckel's diverticulum. Histopathology revealed a similar 10-mm nodule of fully formed pancreatic tissue in the ileal serosal tissues, with some acinar tissue extending through the wall of the intestine alongside ductal structures. In both cases there was ectopic gastric mucosa either in the distal part of the draining duct or in the small intestine itself at the opening. Heterotopic pancreas is a rare cause of intussusception. We propose that this lesion is of vitellointestinal tract origin, conceptually similar to a Meckel's diverticulum but without a diverticulum as such. Heterotopic pancreatic tissue occurring alone is more common in the proximal small intestine, duodenum, and stomach than in the ileum, and it is often asymptomatic.

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Cholecystitis Associated with Heterotopic Pancreas, Pseudopyloric Metaplasia, and Adenomyomatous Hyperplasia: A Rare Combination

Journal of Laboratory Physicians ◽

10.4103/0974-2727.180795 ◽

2016 ◽

Vol 8 (02) ◽

pp. 126-128 ◽

Cited By ~ 1

Author(s):

Navjot Kaur ◽

Bal Chander ◽

Harjit Kaur ◽

Rashmi Kaul

Keyword(s):

Gall Bladder ◽

Incidental Finding ◽

Acalculous Cholecystitis ◽

Causative Factor ◽

Pancreatic Tissue ◽

Heterotopic Pancreas ◽

Pathological Examination ◽

Heterotopic Pancreatic Tissue ◽

Rare Combination ◽

Adenomyomatous Hyperplasia

ABSTRACTHeterotopic pancreatic tissue in the gall bladder is an uncommon incidental finding in most cases. We hereby describe the case of a 45-year-old woman who presented with symptoms of acalculous cholecystitis. Pathological examination detected heterotopic pancreatic tissue, pseudopyloric metaplasia, and adenomyomatous hyperplasia in the gall bladder. This is a rare combination of three entities which is being reported for the first time. This case emphasizes that heterotopic pancreas might be the causative factor for cholecystitis.

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Preoperatively diagnosed gastric collision tumor with mixed adenocarcinoma and gastrointestinal stromal tumor: a case report and literature review

Clinical Journal of Gastroenterology ◽

10.1007/s12328-021-01343-4 ◽

2021 ◽

Author(s):

Kunihiko Matsuno ◽

Yoshikazu Kanazawa ◽

Daisuke Kakinuma ◽

Nobutoshi Hagiwara ◽

Fumihiko Ando ◽

...

Keyword(s):

Gastrointestinal Stromal Tumor ◽

Distal Gastrectomy ◽

Submucosal Tumor ◽

Smooth Muscle Actin ◽

Collision Tumor ◽

Stromal Tumor ◽

Lower Body ◽

Muscle Actin ◽

First Case ◽

S 100

AbstractReports of gastric collision tumors, comprising adenocarcinoma and gastrointestinal stromal tumor, are extremely rare. Here, we report the case of a 68-year-old male who was diagnosed with a lower-body, moderately differentiated, tubular-type adenocarcinoma and submucosal tumor and underwent an elective D2 distal gastrectomy. The tumor cells of the gastrointestinal stromal tumor were positive for H-caldesmon and CD117, weakly positive for smooth muscle actin and DOG-1, and negative for desmin, S-100 protein, CD31, and AE1/AE3. The tumor had grown into a mixed form of adenocarcinoma and gastrointestinal stromal tumor. Thus, we report the first case of a preoperatively diagnosed collision tumor in the stomach consisting of adenocarcinoma and gastrointestinal stromal tumor.

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A Triad of Congenital Diaphragmatic Hernia, Meckel’s Diverticulum, and Heterotopic Pancreas

Case Reports in Pediatrics ◽

10.1155/2014/725945 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3

Author(s):

Parkash Mandhan ◽

Amer Al Saied ◽

Mansour J. Ali

Keyword(s):

Case Report ◽

Congenital Diaphragmatic Hernia ◽

Diaphragmatic Hernia ◽

Chromosomal Abnormalities ◽

Meckel’S Diverticulum ◽

Pancreatic Tissue ◽

Meckel's Diverticulum ◽

Developmental Anomaly ◽

Heterotopic Pancreatic Tissue ◽

First Case

Congenital diaphragmatic hernia is a common developmental anomaly encountered by paediatric surgeons. It is known to be associated with extradiaphragmatic malformations, which include cardiac, renal, genital, and chromosomal abnormalities. Herein, we report a newborn born with concurrent congenital diaphragmatic hernia, Meckel’s diverticulum, and heterotopic pancreatic tissue. This is the first case report of such a triad with description of possible mechanisms of the development.

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A RARE CASE OF HETEROTOPIC PANCREATIC TISSUE CAUSING SMALL BOWEL OBSTRUCTION

10.36106/gjra/0202569 ◽

2021 ◽

pp. 4-5

Author(s):

B. Santhi ◽

M. Annapoorani ◽

Sharada bhavana

Keyword(s):

Intestinal Obstruction ◽

Rare Case ◽

Histopathological Examination ◽

Pancreatic Tissue ◽

Acute Intestinal Obstruction ◽

Emergency Laparotomy ◽

Review Of Literature ◽

Heterotopic Pancreatic Tissue ◽

Small Growth ◽

Upper Gastrointestinal

A Rare case of heterotopic pancreatic tissue of ileum causing acute intestinal obstruction has been described with a brief review of literature. A 42 yr old male patient presented to the emergency department with features of acute intestinal obstruction. After evaluation patient was taken up for emergency laparotomy which revealed a band to be arising from ileum. Furthermore, there was a small growth in the ileal wall at the site of origin of the band. Hence resection of the growth was done and followed by ileoileal anastomosis. Later on, histopathological examination of the growth revealed it to be heterotopic pancreatic tissue. Heterotopic pancreatic tissue is often an incidental nding encountered in upper gastrointestinal tract during endoscopy and surgeries. But Symptomatic ectopic pancreas of ileum is relatively rare and they very rarely present with acute symptoms as in this case

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