scholarly journals The Ratio of the Hemoglobin to Red Cell Distribution Width Combined with the Ratio of Platelets to Lymphocytes Can Predict the Survival of Patients with Gastric Cancer Liver Metastasis

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Zhao Zhai ◽  
Jialiang Gao ◽  
Ziyu Zhu ◽  
Xiliang Cong ◽  
Shenghan Lou ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Liver Metastasis ◽  
Liver Metastases ◽  
Scoring System ◽  
Prognostic Nutritional Index ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio

Background. Hemoglobin/red cell distribution width (HR) and platelet/lymphocyte (PLR) ratios are considered effective prognostic markers in various cancers. We have proposed a new prognostic parameter: HR+PLR. The aim of this study is to explore the prognostic value of the HR+PLR scoring system in patients with gastric cancer liver metastasis. Methods. This study retrospectively analyzed the clinical data of 306 patients with gastric cancer liver metastases admitted to our hospital from 2007 to 2014. According to the size of HR value and PLR value, we will divide the patients into three groups, namely, HR+PLR: (1) 0 points: HR > 1.02 and PLR < 128 ; (2) 1 point: HR > 1.02 and PLR > 128 and HR < 1.02 and PLR < 128 ; and (3) 2 points: HR < 1.02 and PLR > 128 . Results. The HR+PLR score was statistically different from age ( P = 0.049 ), T stage ( P < 0.001 ), N stage ( P = 0.017 ), number of liver metastases ( P = 0.018 ), gastrectomy ( P < 0.001 ), hepatectomy ( P = 0.001 ), peritoneal metastasis ( P = 0.012 ), prognostic nutritional index (PNI) ( P = 0.028 ), and neutrophil/lymphocyte ratio (NLR) ( P = 0.045 ). The HR+PLR scoring system has a higher area under the ROC curve (AUC value) than PNI, PLR, HR, and PLR ( AUC = 0.798 , P < 0.001 ). In multivariate analysis, gastrectomy ( P = 0.001 ), hepatectomy ( P < 0.001 ), chemotherapy ( P = 0.014 ), and HR+PLR score ( P < 0.001 ) were considered independent prognostic factors. Conclusion. For patients with gastric cancer liver metastasis, the HR+PLR score is a simple, reliable, and economic prognostic marker.

Red cell distribution width and neutrophil–lymphocyte ratio in rheumatoid arthritis

2020 ◽  
Vol 40 (10) ◽  
pp. 1631-1637
Author(s):  
Patricia Pauline M. Remalante ◽  
Evelyn O. Salido ◽  
Ester G. Penserga ◽  
Deonne Thaddeus V. Gauiran
Keyword(s):  
Rheumatoid Arthritis ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Role of Red Cell Distribution Width and Neutrophil: Lymphocyte Ratio in Adults with Sepsis

2021 ◽  
Vol 13 (03) ◽  
pp. 50-53
Author(s):  
Pavan MR ◽  
Madhav H Hande ◽  
Jayakumar Jeganathan ◽  
Meenakshi Shetty ◽  
Chakrapani M
Keyword(s):  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

Prognostic Significance of Pre- and Post-operative Red-Cell Distribution Width in Patients with Gastric Cancer

2019 ◽  
Vol 24 (5) ◽  
pp. 1010-1017 ◽  
Author(s):  
Shimizu Shota ◽  
Hiroaki Saito ◽  
Yusuke Kono ◽  
Yuki Murakami ◽  
Yuji Shishido ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Significance ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width

The importance of red cell distribution width on gastric cancer.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15502-e15502
Author(s):  
Dilek Erdem ◽  
Emre Erdem ◽  
Yasemin Turgut Kurt ◽  
Turkan Topcu ◽  
Turgut Kacan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Healthy Subjects ◽  
Neutrophil To Lymphocyte Ratio ◽  
Red Cell Distribution Width ◽  
Chronic Obstructive ◽  
Red Cell ◽  
Cell Distribution ◽  
Platelet To Lymphocyte Ratio ◽  
Distribution Width ◽  
Lymphocyte Ratio

e15502 Background: Red cell distribution width (RDW) is an elevated marker in several cancers like breast, colon, prostate and pancreatic cancer at the time of diagnosis. Gastric cancer (GC) is the fifth most common cancer and also third leading cause of cancer deaths.We aimed to determine whether RDW values differ between gastric cancer and healthy subjects, as well as to evaluate association between RDW and other factors. Also, we examined other two important inflammatory markers in GC patients: neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) Methods: This retrospective study included 68 gastric cancer patients and 42 age and sex matched healthy controls. The exclusion criteria involved cardiac disease, chronic obstructive lung disease, thromboembolism, chronic renal failure, hepatic disorders, hypertension, acute and chronic infections, stroke, hematologic disease and other accompanying cancer. Blood samples were retrospectively obtained from computerized patient database. Results: Among 110 subjects; RDW, NLR and PLR were significantly higher in GC patients when compared to healthy subjects (RDW: 44,9 vs 41,4 p < 0.0001, NLR: 3,40 vs 1,90 p < 0.0001, PLR: 245,9 vs 131,1 p = 0.007). There was no statistically significant association between these markers (RDW, NLR and PLR) and stage, histopathological subgroups and metastasis stage at the time of diagnosis. Conclusions: Elevated RDW is a simple, cheap and readily available marker and may be useful in gastric cancer at the time of diagnosis. Also, NLR and PLR can accompany RDW in the assessment of gastric cancer. Key words: gastric, red cell distribution width, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, cancer

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