scholarly journals Delayed CPAP-Induced Pneumocephalus and Meningitis Posttranssphenoidal Surgery

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Tara D’Ignazio ◽  
Mary Francispillai ◽  
Marc Giroux ◽  
Martin Albert

Transsphenoidal surgery (TSS) is a frequently used technique to remove pituitary adenomas. Rare complications of TSS include development of postoperative pneumocephalus. Many patients undergoing TSS also suffer from obstructive sleep apnea (OSA) and thus require positive pressure ventilation. The exact timing of when to safely reintroduce the CPAP machine in this subset of patients is presently not exactly known but is most often cited as being two to four weeks postoperatively. In this case, we describe the story of a 69-year-old female who underwent TSS for a nonsecreting pituitary adenoma in April 2012 and went on to develop pneumocephalus five weeks postoperatively after reintroduction of her CPAP machine. This is the latest presentation of pneumocephalus after reintroduction of CPAP documented in present literature. The case reopens the debate as to how many weeks postoperatively positive pressure ventilation should be withheld to prevent the development of pneumocephalus in patients having undergone TSS with simultaneous OSA.


2019 ◽  
Vol 81 (03) ◽  
pp. 237-243 ◽  
Author(s):  
Nicholas Gravbrot ◽  
Heidi Jahnke ◽  
William L. White ◽  
Andrew S. Little

Objectives Transsphenoidal surgery creates a skull base defect that may cause postoperative cerebrospinal fluid (CSF) leakage or pneumocephalus. This study reviewed the institutional experience of a pituitary center in managing patients who use positive-pressure ventilation (PPV) devices for obstructive sleep apnea (OSA) after transsphenoidal surgery, which risks disturbing the skull base repair. Design Retrospective review. Setting Pituitary referral center in a major metropolitan medical center. Methods PPV was resumed at the discretion of the treatment team based on intraoperative findings and OSA severity. Perioperative complications related to resuming and withholding PPV were recorded. Participants Transsphenoidal surgery patients with OSA using PPV devices. Main Outcome Measures Intracranial complications before and after resuming PPV. Results A total of 42 patients met the study criteria. Intraoperative CSF leakage was encountered and repaired in 20 (48%) patients. Overall, 38 patients resumed PPV (median: 3.5 weeks postsurgery; range: 0.14–52 weeks) and 4 patients did not resume PPV. Postoperatively, no patient experienced CSF leakage or pneumocephalus before or after resuming PPV. Four (10%) patients required temporary nocturnal supplemental oxygen at home, one patient was reintubated after a myocardial infarction, and one patient had a prolonged hospital stay due to chronic obstructive pulmonary disease exacerbation. Conclusions Resuming PPV use after transsphenoidal surgery did not result in intracranial complications. However, delay in resuming PPV resulted in four patients requiring oxygen at home. We propose a preliminary PPV device management algorithm based on the size of the intraoperative CSF leak to facilitate future studies.



2015 ◽  
Vol 30 (4) ◽  
pp. e5
Author(s):  
Kimberly Latham ◽  
Tamera Bird ◽  
Joyce Burke ◽  
Molly Johantgen ◽  
Victoria Martin ◽  
...  






SLEEP ◽  
2011 ◽  
Vol 34 (3) ◽  
pp. 303-314 ◽  
Author(s):  
Stuart F. Quan ◽  
Cynthia S. Chan ◽  
William C. Dement ◽  
Alan Gevins ◽  
James L. Goodwin ◽  
...  


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