Phase I Trial of Panobinostat (LBH589) in Combination with Trastuzumab in Pretreated HER2-Positive Metastatic Breast Cancer (mBC): Preliminary Safety, Efficacy and Pharmacokinetic Results.

Phase I ◽

Phase I Trial ◽

Metastatic Breast ◽

Faculty of 1000 evaluation for Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718102079.793485106 ◽

2013 ◽

Author(s):

Ana Maria Gonzalez-Angulo

Keyword(s):

Breast Cancer ◽

Brain Metastases ◽

Phase I ◽

Phase I Trial ◽

Metastatic Breast ◽

Abstract P4-12-24: Phase I trial of S-222611, a dual tyrosine kinase inhibitor of EGFR and HER2, with preliminary evidence of efficacy in patients (pts) with heavily-pretreated HER2-positive metastatic breast cancer

10.1158/0008-5472.sabcs13-p4-12-24 ◽

2013 ◽

Cited By ~ 1

Author(s):

RD Baird ◽

N Cresti ◽

E Beddowes ◽

M Saggese ◽

M Flynn ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Tyrosine Kinase Inhibitor ◽

Phase I Trial ◽

Kinase Inhibitor ◽

Metastatic Breast ◽

Preliminary Evidence ◽

Her2 Positive ◽

Heavily Pretreated

Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial

Annals of Oncology ◽

10.1093/annonc/mdt359 ◽

2013 ◽

Vol 24 (12) ◽

pp. 2985-2989 ◽

Cited By ~ 15

Author(s):

E. de Azambuja ◽

D. Zardavas ◽

M. Lemort ◽

J. Rossari ◽

C. Moulin ◽

...

Keyword(s):

Breast Cancer ◽

Brain Metastases ◽

Phase I ◽

Phase I Trial ◽

Metastatic Breast ◽

A Phase I Trial of the PI3K Inhibitor Buparlisib Combined With Capecitabine in Patients With Metastatic Breast Cancer

Clinical Breast Cancer ◽

10.1016/j.clbc.2017.10.014 ◽

2018 ◽

Vol 18 (4) ◽

pp. 289-297 ◽

Cited By ~ 9

Author(s):

Autumn J. McRee ◽

Paul K. Marcom ◽

Dominic T. Moore ◽

William C. Zamboni ◽

Zachary A. Kornblum ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Trial ◽

Metastatic Breast ◽

Pi3k Inhibitor

122 O - A phase I trial of epirubicin (E) and paclitaxel (P) in patients with metastatic breast cancer (MBC)

European Journal of Cancer ◽

10.1016/0959-8049(96)84879-9 ◽

1996 ◽

Vol 32 ◽

pp. S24

Author(s):

R. Salyadori ◽

A. Mlchelotti ◽

E. Baldini ◽

A. Gennari ◽

C. Tibaldi ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Trial ◽

Metastatic Breast

Phase I trial of liposomal doxorubicin and ZD1839 in patients with refractory gynecological malignancies or metastatic breast cancer

International Journal of Clinical Oncology ◽

10.1007/s10147-010-0073-6 ◽

2010 ◽

Vol 15 (4) ◽

pp. 390-398 ◽

Cited By ~ 4

Author(s):

Susana M. Campos ◽

Suzanne T. Berlin ◽

Leroy M. Parker ◽

Wendy Y. Chen ◽

Craig A. Bunnell ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Trial ◽

Liposomal Doxorubicin ◽

Metastatic Breast ◽

Gynecological Malignancies

Abstract P5-20-13: Preliminary report of a phase I/II study of entinostat (IND#NSC 706995, /M275) and lapatinib (IND#NSC 727989) in patients with HER2-positive metastatic breast cancer in whom trastuzumab has failed

10.1158/0008-5472.sabcs12-p5-20-13 ◽

2012 ◽

Author(s):

NT Ueno ◽

SA Jackson ◽

RH Alvarez ◽

JS Willey ◽

GN Hortobagyi ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Preliminary Report ◽

Metastatic Breast ◽

Abstract 5468: GEP01: A phase I pharmacokinetic study of lapatinib and iv vinorelbine in the treatment of HER2-positive locally advanced or metastatic breast cancer

10.1158/1538-7445.am2011-5468 ◽

2011 ◽

Author(s):

Keyvan Rezai ◽

Nicolas Isambert ◽

Etienne Brain ◽

Florence Dalenc ◽

Saïk Urien ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Pharmacokinetic Study ◽

Locally Advanced ◽

Metastatic Breast ◽

Abstract P4-21-08: A phase I/II of S-222611, a reversible EGFR and HER2 inhibitor, combined with trastuzumab +/- chemotherapy in patients with HER2-positive metastatic breast cancer

10.1158/1538-7445.sabcs16-p4-21-08 ◽

2017 ◽

Cited By ~ 1

Author(s):

S Rafii ◽

I Macpherson ◽

R Baird ◽

M Saggese ◽

P Spiliopoulou ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Metastatic Breast ◽

Balixafortide (a novel CXCR4 inhibitor) and eribulin in HER2-neg metastatic breast cancer (MBC) patients (pts): A phase I trial

Annals of Oncology ◽

10.1093/annonc/mdy272.277 ◽

2018 ◽

Vol 29 ◽

pp. viii91-viii92

Author(s):

J. Cortes Castan ◽

M. Martín ◽

S. Pernas Simon ◽

P. Gomez Pardo ◽

S. Lopez-Tarruella ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase I Trial ◽

Metastatic Breast