G3139, an Anti-Bcl-2 Antisense Oligomer That Binds Heparin-Binding Growth Factors and Collagen I, Alters In vitro Endothelial Cell Growth and Tubular Morphogenesis

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-08-2610 ◽

2009 ◽

Vol 15 (8) ◽

pp. 2797-2807 ◽

Author(s):

C.A. Stein ◽

SiJian Wu ◽

Anatoliy M. Voskresenskiy ◽

Jin-Feng Zhou ◽

Joongho Shin ◽

...

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Heparin Binding ◽

Heparin Binding Growth Factors ◽

Endothelial Cell Growth ◽

Antisense Oligomer

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Enhanced Ability of Heparin-Carrying Polystyrene (HCPS) to Bind to Heparin-Binding Growth Factors and to Inhibit Growth Factor-Induced Endothelial Cell Growth

The Journal of Biochemistry ◽

10.1093/oxfordjournals.jbchem.a022672 ◽

2000 ◽

Vol 127 (5) ◽

pp. 797-803 ◽

Author(s):

M. Ishihara ◽

K. Ono ◽

K. Ishikawa ◽

H. Hattori ◽

Y. Saito ◽

...

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Growth Factor ◽

Cell Growth ◽

Heparin Binding ◽

Heparin Binding Growth Factors ◽

Endothelial Cell Growth

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Alteration of in vitro human decidual endothelial cell growth, endothelin-1 and prostaglandin secretion, by growth factors and intracellular calcium

Prostaglandins Leukotrienes and Essential Fatty Acids ◽

10.1016/s0952-3278(96)90024-1 ◽

1996 ◽

Vol 54 (6) ◽

pp. 411-418

Author(s):

E.D.M Gallery ◽

J. Rowe ◽

S. Campbell

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Intracellular Calcium ◽

Endothelin 1 ◽

Endothelial Cell Growth

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Purification and characterization of heparin-binding endothelial cell growth factors.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)36031-3 ◽

1986 ◽

Vol 261 (4) ◽

pp. 1924-1928

Author(s):

R Lobb ◽

J Sasse ◽

R Sullivan ◽

Y Shing ◽

P D'Amore ◽

...

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Heparin Binding ◽

Purification And Characterization ◽

Endothelial Cell Growth

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Storage of Heparin-Binding Endothelial Cell Growth Factors in the Cornea: a New Mechanism for Corneal Neovascularization

Documenta Ophthalmologica Proceedings Series - Ocular Circulation and Neovascularization ◽

10.1007/978-94-009-3337-8_73 ◽

1987 ◽

pp. 489-498

Author(s):

Israel Vlodavsky ◽

Michael Klagsbrun ◽

Judah Folkman

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Corneal Neovascularization ◽

Heparin Binding ◽

Endothelial Cell Growth

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Vascular Endothelial Cell Growth Factors Promote the In Vitro Development of Rat Photoreceptor Cells

Journal of Neuroscience ◽

10.1523/jneurosci.20-18-06781.2000 ◽

2000 ◽

Vol 20 (18) ◽

pp. 6781-6788 ◽

Author(s):

Pamela A. Yourey ◽

Shiva Gohari ◽

Jeffery L. Su ◽

Ralph F. Alderson

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Vascular Endothelial Cell ◽

Photoreceptor Cells ◽

Vascular Endothelial ◽

In Vitro Development ◽

Endothelial Cell Growth ◽

Vitro Development

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Controlled Release of Endothelial Cell Growth Factor from Chitosan-Albumin Microspheres for Localized Angiogenesis: In Vitro and in Vivo Studies

Artificial Cells Blood Substitutes and Biotechnology ◽

10.3109/10731199609117438 ◽

1996 ◽

Vol 24 (3) ◽

pp. 257-271 ◽

Author(s):

Y. Murat Elçin ◽

Vivek Dixit ◽

Gary Gitnick

Keyword(s):

Endothelial Cell ◽

Controlled Release ◽

Growth Factor ◽

Cell Growth ◽

In Vivo Studies ◽

Albumin Microspheres ◽

Endothelial Cell Growth Factor ◽

Endothelial Cell Growth

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IN VITRO INHIBITION OF KSHV/HHV-8 INFECTED ENDOTHELIAL CELL GROWTH BY NEUTRALIZING MONOCLONAL ANTIBODIES TO HUMAN VEGFR-2 (KDR)

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/00126334-199905010-00096 ◽

1999 ◽

Vol 21 (1) ◽

pp. A28

Author(s):

Sarah Nikolovska ◽

Afzal J. Naiyer ◽

Ornella Flore ◽

Mario Peichev ◽

Larry Witte ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Endothelial Cell ◽

Cell Growth ◽

In Vitro Inhibition ◽

Endothelial Cell Growth ◽

Infected Endothelial Cell

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Heparin affinity of anionic and cationic capillary endothelial cell growth factors: analysis of hypothalamus-derived growth factors and fibroblast growth factors.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.82.3.805 ◽

1985 ◽

Vol 82 (3) ◽

pp. 805-809 ◽

Author(s):

M. Klagsbrun ◽

Y. Shing

Keyword(s):

Growth Factors ◽

Endothelial Cell ◽

Cell Growth ◽

Fibroblast Growth Factors ◽

Fibroblast Growth ◽

Capillary Endothelial Cell ◽

Factors Analysis ◽

Endothelial Cell Growth ◽

Heparin Affinity

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Identification of non heparin-binding endothelial cell growth factor from rat myofibroblasts

Experientia Supplementum - Angiogenesis ◽

10.1007/978-3-0348-7001-6_27 ◽

1992 ◽

pp. 179-187

Author(s):

Noboru Sato ◽

Nobuo Tsuruoka ◽

Mikio Yamamoto ◽

Tatsuro Nishihara ◽

Tamotsu Goto

Keyword(s):

Endothelial Cell ◽

Growth Factor ◽

Cell Growth ◽

Heparin Binding ◽

Endothelial Cell Growth Factor ◽

Endothelial Cell Growth

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Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene

Molecular and Cellular Biology ◽

10.1128/mcb.11.4.2125-2132.1991 ◽

1991 ◽

Vol 11 (4) ◽

pp. 2125-2132

Author(s):

K Hagiwara ◽

G Stenman ◽

H Honda ◽

P Sahlin ◽

A Andersson ◽

...

Keyword(s):

Endothelial Cell ◽

Growth Factor ◽

Cell Growth ◽

Human Platelet ◽

Angiogenic Factor ◽

Transcription Start Sites ◽

Endothelial Cell Growth Factor ◽

Endothelial Cell Growth

Human platelet-derived endothelial cell growth factor (hPD-ECGF) is a novel angiogenic factor which stimulates endothelial cell growth in vitro and promotes angiogenesis in vivo. We report here the cloning and sequencing of the gene for hPD-ECGF and its flanking regions. This gene is composed of 10 exons dispersed over a 4.3-kb region. Its promoter lacks a TATA box and a CCAAT box, structures characteristic of eukaryotic promoters. Instead, six copies of potential Sp1-binding sites (GGGCGG or CCGCCC) were clustered just upstream of the transcription start sites. Southern blot analysis using genomic DNAs from several vertebrates suggested that the gene for PD-ECGF is conserved phylogenetically among vertebrates. The gene for hPD-ECGF was localized to chromosome 22 by analysis of a panel of human-rodent somatic cell hybrid lines.

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