Abstract C194:In vivocharacterization of AMG 900, an orally active small molecule inhibitor of aurora kinases in phase 1 clinical trials

2009 ◽  
Author(s):  
Tammy L. Bush ◽  
Beth Ziegler ◽  
Grace Chung ◽  
Patricia L. McElroy ◽  
Richard Kendall ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Small Molecule ◽  
Phase 1 ◽  
Small Molecule Inhibitor ◽  
Aurora Kinases ◽  
Molecule Inhibitor ◽  
Orally Active

scholarly journals Identification of a lead small-molecule inhibitor of the Aurora kinases using a structure-assisted, fragment-based approach

2006 ◽  
Vol 5 (7) ◽  
pp. 1764-1773 ◽  
Author(s):  
Steven L. Warner ◽  
Sridevi Bashyam ◽  
Hariprasad Vankayalapati ◽  
David J. Bearss ◽  
Haiyong Han ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Aurora Kinases ◽  
Molecule Inhibitor

scholarly journals Efficacy of Immunobiologic and Small Molecule Inhibitor Drugs for Psoriasis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Drugs in R&D ◽  
2016 ◽  
Vol 17 (1) ◽  
pp. 29-51 ◽  
Author(s):  
André Vicente Esteves de Carvalho ◽  
Rodrigo Pereira Duquia ◽  
Bernardo Lessa Horta ◽  
Renan Rangel Bonamigo
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Small Molecule ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor

scholarly journals Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

2007 ◽  
Vol 104 (10) ◽  
pp. 4106-4111 ◽  
Author(s):  
M. G. Manfredi ◽  
J. A. Ecsedy ◽  
K. A. Meetze ◽  
S. K. Balani ◽  
O. Burenkova ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Aurora A Kinase ◽  
Aurora A ◽  
Molecule Inhibitor ◽  
Orally Active
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