Abstract B102: 19-Substituted benzoquinone ansamycins: Decreasing the toxicity of the benzoquinone ansamycin class of Hsp90 inhibitors.

2011 ◽  
Author(s):  
Chuan-Hsin Chang ◽  
Russell Kitson ◽  
Philip Reigan ◽  
David Siegel ◽  
Christopher J. Moody ◽  
...  
Keyword(s):  
Hsp90 Inhibitors ◽  
Benzoquinone Ansamycin

Abstract 1791: 19-Substituted benzoquinone ansamycin Hsp90 inhibitors: Effects on Hsp90 co-chaperones and Hsp90-Hsf1 complexes in cellular systems

2014 ◽  
Author(s):  
Derek A. Drechsel ◽  
Chuan-Hsin Chang ◽  
Russell Kitson ◽  
David Siegel ◽  
Christopher J. Moody ◽  
...  
Keyword(s):  
Cellular Systems ◽  
Hsp90 Inhibitors ◽  
Benzoquinone Ansamycin

C-terminal Hsp90-inhibitors restore glucocorticoid sensitivity in Cushing's disease

2013 ◽  
Vol 121 (10) ◽  
Author(s):  
M Riebold ◽  
M Theodoropoulou ◽  
C Kozany ◽  
F Hausch ◽  
GK Stalla ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Hsp90 Inhibitors ◽  
Glucocorticoid Sensitivity

Discovery and Development of Pyrazole-Scaffold Hsp90 Inhibitors

2006 ◽  
Vol 6 (11) ◽  
pp. 1193-1203 ◽  
Author(s):  
Edward McDonald ◽  
Keith Jones ◽  
Paul Brough ◽  
Martin Drysdale ◽  
Paul Workman
Keyword(s):  
Hsp90 Inhibitors

scholarly journals The Anticancer Drug AUY922 Generates a Proteomics Fingerprint That Is Highly Conserved among Structurally Diverse Hsp90 Inhibitors

2013 ◽  
Vol 12 (8) ◽  
pp. 3697-3706 ◽  
Author(s):  
Sudhakar Voruganti ◽  
Jeff C. LaCroix ◽  
Chelsea N. Rogers ◽  
Janet Rogers ◽  
Robert L. Matts ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Hsp90 Inhibitors

scholarly journals 19-Substituted Benzoquinone Ansamycin Heat Shock Protein-90 Inhibitors: Biological Activity and Decreased Off-Target Toxicity

2014 ◽  
Vol 85 (6) ◽  
pp. 849-857 ◽  
Author(s):  
Chuan-Hsin Chang ◽  
Derek A. Drechsel ◽  
Russell R. A. Kitson ◽  
David Siegel ◽  
Qiang You ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 90 ◽  
Benzoquinone Ansamycin
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