Abstract 4975: The role of the Ikaros transcription factor in regulatory T cell (Treg) development and function in a murine pancreatic adenocarcinoma model.

2013 ◽  
Author(s):  
Nadine Nelson ◽  
Maya Jerald ◽  
Laura Pendleton ◽  
Karoly Szekeres ◽  
Nasreen Vohra ◽  
...  
Keyword(s):  
Transcription Factor ◽  
T Cell ◽  
Pancreatic Adenocarcinoma ◽  
Regulatory T Cell ◽  
And Function ◽  
Treg Development

scholarly journals Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Mark Engel ◽  
Tom Sidwell ◽  
Ajithkumar Vasanthakumar ◽  
George Grigoriadis ◽  
Ashish Banerjee
Keyword(s):  
T Cells ◽  
Transcription Factors ◽  
T Cell ◽  
Regulatory T Cells ◽  
Immune Tolerance ◽  
Regulatory T Cell ◽  
T Cell Development ◽  
Signalling Pathways ◽  
Treg Development

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

scholarly journals An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function

Immunity ◽  
2017 ◽  
Vol 47 (3) ◽  
pp. 450-465.e5 ◽  
Author(s):  
Hyunju Oh ◽  
Yenkel Grinberg-Bleyer ◽  
Will Liao ◽  
Dillon Maloney ◽  
Pingzhang Wang ◽  
...  
Keyword(s):  
Transcription Factor ◽  
T Cell ◽  
Regulatory T Cell ◽  
Transcriptional Program ◽  
Cell Identity ◽  
And Function

scholarly journals The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

2009 ◽  
Vol 10 (6) ◽  
pp. 595-602 ◽  
Author(s):  
Meghan A Koch ◽  
Glady's Tucker-Heard ◽  
Nikole R Perdue ◽  
Justin R Killebrew ◽  
Kevin B Urdahl ◽  
...  
Keyword(s):  
Transcription Factor ◽  
T Cell ◽  
Regulatory T Cell ◽  
T Cell Homeostasis ◽  
Cell Homeostasis ◽  
And Function

scholarly journals Role of Cytokines in Thymus- Versus Peripherally Derived-Regulatory T Cell Differentiation and Function

2013 ◽  
Vol 4 ◽  
Author(s):  
Jérémie David Goldstein ◽  
Louis Pérol ◽  
Bruno Zaragoza ◽  
Audrey Baeyens ◽  
Gilles Marodon ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
T Cell ◽  
Regulatory T Cell ◽  
T Cell Differentiation ◽  
And Function

The Role of Foxp3 in Regulatory T Cell Differentiation and Function

2009 ◽  
Vol 5 (2) ◽  
pp. 89-101 ◽  
Author(s):  
Gurman Kaur ◽  
Robert Busch ◽  
J.S. Gaston
Keyword(s):  
Cell Differentiation ◽  
T Cell ◽  
Regulatory T Cell ◽  
T Cell Differentiation ◽  
And Function
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