Abstract 1194: Discovery and preclinical development of a highly potent NaPi2b-targeted antibody-drug conjugate (ADC) with significant activity in patient-derived non-small cell lung cancer (NSCLC) xenograft models

2016 ◽  
Author(s):  
Natalya Bodyak ◽  
Alex Yurkovetskiy ◽  
Mao Yin ◽  
Dmitry Gumerov ◽  
Reddy Bollu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Significant Activity ◽  
Small Cell Lung ◽  
Antibody Drug Conjugate ◽  
Preclinical Development ◽  
Xenograft Models ◽  
Antibody Drug

scholarly journals Lorvotuzumab mertansine, a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models

mAbs ◽  
2014 ◽  
Vol 6 (2) ◽  
pp. 556-566 ◽  
Author(s):  
Kathleen R Whiteman ◽  
Holly A Johnson ◽  
Michele F Mayo ◽  
Charlene A Audette ◽  
Christina N Carrigan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Antitumor Activity ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Antibody Drug Conjugate ◽  
Xenograft Models ◽  
Antibody Drug ◽  
Human Xenograft Models
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