Abstract 2377: Design, synthesis, and characterization of 4-aminopyrazole quinazolines as potent inhibitors of G protein-coupled receptor kinase GRK6 for the potential treatment of multiple myeloma

Potential Treatment ◽

Receptor Kinase ◽

Design Synthesis ◽

Correction to “Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma”

10.1021/acs.jmedchem.1c02066 ◽

2021 ◽

Author(s):

David E. Uehling ◽

Babu Joseph ◽

Kim Chan Chung ◽

Andrew X. Zhang ◽

Spencer Ler ◽

...

Keyword(s):

Multiple Myeloma ◽

G Protein ◽

Receptor Kinase ◽

Design Synthesis ◽

Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma

10.1021/acs.jmedchem.1c00506 ◽

2021 ◽

Author(s):

David E. Uehling ◽

Babu Joseph ◽

Kim Chan Chung ◽

Andrew X. Zhang ◽

Spencer Ler ◽

...

Keyword(s):

Multiple Myeloma ◽

G Protein ◽

Receptor Kinase ◽

Design Synthesis ◽

Identification and characterization of inhibitors of G protein-coupled receptor kinase 6 (GRK6) as potential therapeutics for multiple myeloma

Qatar Foundation Annual Research Forum Proceedings ◽

10.5339/qfarf.2012.aesnp12 ◽

2012 ◽

pp. AESNP12 ◽

Cited By ~ 1

Author(s):

Rima Al-awar ◽

David Uehling ◽

Babu Joseph ◽

Carly Griffin ◽

Ratheesh Subramaniam ◽

...

Keyword(s):

Multiple Myeloma ◽

G Protein ◽

Receptor Kinase ◽

G Protein Coupled ◽

Identification And Characterization ◽

Potential Therapeutics

Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68)

10.1021/acs.jmedchem.9b00869 ◽

2019 ◽

Vol 62 (16) ◽

pp. 7557-7574 ◽

Cited By ~ 3

Author(s):

Xufen Yu ◽

Xi-Ping Huang ◽

Terry P. Kenakin ◽

Samuel T. Slocum ◽

Xin Chen ◽

...

Keyword(s):

G Protein ◽

Allosteric Modulators ◽

Design Synthesis ◽

Positive Allosteric Modulators ◽

Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure

10.1021/acs.jmedchem.7b00443 ◽

2017 ◽

Vol 60 (16) ◽

pp. 6942-6990 ◽

Cited By ~ 20

Author(s):

Tomohiro Okawa ◽

Yoshio Aramaki ◽

Mitsuo Yamamoto ◽

Toshitake Kobayashi ◽

Shoji Fukumoto ◽

...

Keyword(s):

Heart Failure ◽

G Protein ◽

Potential Treatment ◽

Receptor Kinase ◽

Design Synthesis ◽

Faculty Opinions recommendation of Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727800973.793535228 ◽

2017 ◽

Author(s):

John Lowe

Keyword(s):

Heart Failure ◽

G Protein ◽

Potential Treatment ◽

Receptor Kinase ◽

Design Synthesis ◽

Abstract 156: Screening and characterization of inhibitors of G-protein coupled receptor kinase GRK6 as potential therapeutics for multiple myeloma

10.1158/1538-7445.am2012-156 ◽

2012 ◽

Author(s):

Carly Griffin ◽

Ratheesh Subramanian ◽

Hassan S. Zaidi ◽

Richard Marcellus ◽

Babu Joseph ◽

...

Keyword(s):

Multiple Myeloma ◽

G Protein ◽

Receptor Kinase ◽

G Protein Coupled ◽

Potential Therapeutics

Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

Synthesis And Biological Evaluation

Design Synthesis ◽

G Protein Coupled ◽

Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42226-5 ◽

1994 ◽

Vol 269 (2) ◽

pp. 1099-1105 ◽

Cited By ~ 8

Author(s):

P. Kunapuli ◽

J.J. Onorato ◽

M.M. Hosey ◽

J.L. Benovic

Keyword(s):

G Protein ◽

Receptor Kinase ◽

Purification And Characterization ◽

Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma

Protein Expression and Purification ◽

10.1016/j.pep.2021.105890 ◽

2021 ◽

pp. 105890

Author(s):

Tien L. Olson ◽

Shangji Zhang ◽

Dillon Labban ◽

Emily Kaschner ◽

Manuel Aceves ◽

...

Keyword(s):

Multiple Myeloma ◽

Drug Design ◽

Protein Expression ◽

G Protein ◽

Receptor Kinase ◽

Expression And Purification ◽

Structure Based Drug Design ◽

Protein Expression And Purification ◽