Abstract 5735: Amino acid transporter SLC6A14: A novel drug target for colorectal cancer and colitis and its transcriptional regulation by TCF4/beta-catenin pathway

2018 ◽  
Author(s):  
Mohd Omar Sikder ◽  
Sathish Sivaprakasam ◽  
Ganapathy Vadivel
Keyword(s):  
Colorectal Cancer ◽  
Transcriptional Regulation ◽  
Amino Acid ◽  
Drug Target ◽  
Amino Acid Transporter ◽  
Beta Catenin ◽  
Acid Transporter ◽  
Novel Drug

scholarly journals Anti‐tumor effects of an antagonistic mAb against the ASCT2 amino acid transporter on KRAS ‐mutated human colorectal cancer cells

2019 ◽  
Vol 9 (1) ◽  
pp. 302-312 ◽  
Author(s):  
Yuta Hara ◽  
Yushi Minami ◽  
Soshi Yoshimoto ◽  
Natsumi Hayashi ◽  
Akitaka Yamasaki ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Transporter ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Acid Transporter ◽  
Human Colorectal Cancer Cells

scholarly journals Amino acid transporter molecule as a drug target

1999 ◽  
Vol 114 (supplement) ◽  
pp. 11-16 ◽  
Author(s):  
Hitoshi Endou ◽  
Yoshikatsu Kanai
Keyword(s):  
Amino Acid ◽  
Drug Target ◽  
Amino Acid Transporter ◽  
Acid Transporter

scholarly journals Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

2016 ◽  
Vol 173 (23) ◽  
pp. 3292-3306 ◽  
Author(s):  
V Coothankandaswamy ◽  
S Cao ◽  
Y Xu ◽  
P D Prasad ◽  
P K Singh ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Amino Acid ◽  
Drug Target ◽  
Amino Acid Transporter ◽  
Effective Drug ◽  
Acid Transporter

scholarly journals Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB and Yin Yang 1 (YY1)

2015 ◽  
Vol 290 (39) ◽  
pp. 23725-23737 ◽  
Author(s):  
Pratap Karki ◽  
Clifford Kim ◽  
Keisha Smith ◽  
Deok-Soo Son ◽  
Michael Aschner ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Amino Acid ◽  
Excitatory Amino Acid ◽  
Amino Acid Transporter ◽  
Excitatory Amino Acid Transporter ◽  
Yin Yang 1 ◽  
Yin Yang ◽  
Acid Transporter

scholarly journals Positive Relationship between L-type Amino Acid Transporter 1 Expression and Liver Metastasis in T3 Colorectal Cancer

2011 ◽  
Vol 23 (3) ◽  
pp. 145-151
Author(s):  
Kaoru KATO ◽  
Toshiaki KUNIMURA ◽  
Tomohiko YOSHIDA ◽  
Yuichi TAKANO ◽  
Takahiro HOBO ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Amino Acid ◽  
Liver Metastasis ◽  
Positive Relationship ◽  
Amino Acid Transporter ◽  
Acid Transporter

scholarly journals Transcriptional regulation of the sodium‐coupled neutral amino acid transporter (SNAT2) by 17β‐estradiol

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Laura Velazquez‐Villegas ◽  
Victor Ortiz ◽  
David Ordaz‐Rosado ◽  
Rocio Garcia‐Becerra ◽  
Fernando Larrea ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Amino Acid ◽  
Amino Acid Transporter ◽  
Neutral Amino Acid ◽  
Neutral Amino Acid Transporter ◽  
17Β Estradiol ◽  
Acid Transporter
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