Abstract 1036: Discovery of a highly potent, efficacious and orally active small-molecule inhibitor of embryonic ectoderm development (EED)

2020 ◽  
Author(s):  
Changwei Wang ◽  
Rohan Kalyan Rej ◽  
Jianfeng Lu ◽  
Mi Wang ◽  
Kaitlin P. Harvey ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor ◽  
Embryonic Ectoderm Development ◽  
Orally Active ◽  
Embryonic Ectoderm

scholarly journals EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development

2020 ◽  
Vol 63 (13) ◽  
pp. 7252-7267 ◽  
Author(s):  
Rohan Kalyan Rej ◽  
Changwei Wang ◽  
Jianfeng Lu ◽  
Mi Wang ◽  
Elyse Petrunak ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor ◽  
Embryonic Ectoderm Development ◽  
Orally Active ◽  
Embryonic Ectoderm

scholarly journals Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

2007 ◽  
Vol 104 (10) ◽  
pp. 4106-4111 ◽  
Author(s):  
M. G. Manfredi ◽  
J. A. Ecsedy ◽  
K. A. Meetze ◽  
S. K. Balani ◽  
O. Burenkova ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Aurora A Kinase ◽  
Aurora A ◽  
Molecule Inhibitor ◽  
Orally Active

scholarly journals OR22-6 Reversal Of Diet Induced Metabolic Syndrome In Mice With An Orally Active Small Molecule Inhibitor Of PAI-1

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Joshua Levine ◽  
Tianjiao Sun ◽  
Mesut Eren ◽  
Elizabeth Lux ◽  
Toshiyo Miyata ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor ◽  
Orally Active ◽  
Pai 1

scholarly journals Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis

Bone Research ◽  
2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuta Nakai ◽  
Kazuo Okamoto ◽  
Asuka Terashima ◽  
Shogo Ehata ◽  
Jun Nishida ◽  
...  
Keyword(s):  
Bone Metastasis ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor ◽  
Orally Active
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