Abstract 2894: XMT-1592, a site-specific Dolasynthen-based NaPi2b-targeted antibody-drug conjugate for the treatment of ovarian cancer and lung adenocarcinoma

2020 ◽  
Author(s):  
Shawn Fessler ◽  
Anouk Dirksen ◽  
Scott D. Collins ◽  
Ling Xu ◽  
Winnie Lee ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Lung Adenocarcinoma ◽  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Drug Conjugate ◽  
A Site ◽  
Antibody Drug

scholarly journals ARX788, a Site-specific Anti-HER2 Antibody–Drug Conjugate, Demonstrates Potent and Selective Activity in HER2-low and T-DM1–resistant Breast and Gastric Cancers

2020 ◽  
Vol 19 (9) ◽  
pp. 1833-1843 ◽  
Author(s):  
Lillian Skidmore ◽  
Sukumar Sakamuri ◽  
Nick A. Knudsen ◽  
Amha Gebre Hewet ◽  
Snezana Milutinovic ◽  
...  
Keyword(s):  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Gastric Cancers ◽  
Drug Conjugate ◽  
A Site ◽  
Antibody Drug ◽  
Selective Activity

scholarly journals A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

2019 ◽  
Vol 30 (11) ◽  
pp. 2419-2429 ◽  
Author(s):  
Oscar Hernandez-Alba ◽  
Stéphane Houel ◽  
Steve Hessmann ◽  
Stéphane Erb ◽  
David Rabuka ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Specific Antibody ◽  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Drug Conjugate ◽  
Drug Conjugation ◽  
A Site ◽  
Antibody Drug

scholarly journals Targeted Delivery of LXR Agonist Using a Site-Specific Antibody–Drug Conjugate

2015 ◽  
Vol 26 (11) ◽  
pp. 2216-2222 ◽  
Author(s):  
Reyna K. V. Lim ◽  
Shan Yu ◽  
Bo Cheng ◽  
Sijia Li ◽  
Nam-Jung Kim ◽  
...  
Keyword(s):  
Specific Antibody ◽  
Targeted Delivery ◽  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Drug Conjugate ◽  
A Site ◽  
Antibody Drug

RN927C, a Site-Specific Trop-2 Antibody–Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models

2016 ◽  
Vol 15 (11) ◽  
pp. 2698-2708 ◽  
Author(s):  
Pavel Strop ◽  
Thomas-Toan Tran ◽  
Magdalena Dorywalska ◽  
Kathy Delaria ◽  
Russell Dushin ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Tumor Models ◽  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Drug Conjugate ◽  
A Site ◽  
Enhanced Stability ◽  
Antibody Drug

scholarly journals PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers

2020 ◽  
Vol 19 (10) ◽  
pp. 2068-2078 ◽  
Author(s):  
Edmund I. Graziani ◽  
Matthew Sung ◽  
Dangshe Ma ◽  
Bitha Narayanan ◽  
Kimberly Marquette ◽  
...  
Keyword(s):  
Antibody Drug Conjugate ◽  
Site Specific ◽  
Lung Cancers ◽  
Drug Conjugate ◽  
A Site ◽  
Antibody Drug
Sign in / Sign up

Export Citation Format

Share Document