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Abstract 3897: Stability and safety evaluation of STRO-002, a site-specific anti-folate receptor alpha antibody-drug conjugate for the potential treatment of ovarian and endometrial cancers
Mapping Intimacies
◽
10.1158/1538-7445.sabcs18-3897
◽
2019
◽
Author(s):
Willy Solis
◽
Venita De Almeida
◽
Cristina Abrahams
◽
Xiaofan Li
◽
Tyler Heibeck
◽
...
Keyword(s):
Folate Receptor
◽
Safety Evaluation
◽
Potential Treatment
◽
Antibody Drug Conjugate
◽
Site Specific
◽
Receptor Alpha
◽
Drug Conjugate
◽
Endometrial Cancers
◽
A Site
◽
Antibody Drug
Download Full-text
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Cited By
References
Abstract 3897: Stability and safety evaluation of STRO-002, a site-specific anti-folate receptor alpha antibody-drug conjugate for the potential treatment of ovarian and endometrial cancers
10.1158/1538-7445.am2019-3897
◽
2019
◽
Author(s):
Willy Solis
◽
Venita De Almeida
◽
Cristina Abrahams
◽
Xiaofan Li
◽
Tyler Heibeck
◽
...
Keyword(s):
Folate Receptor
◽
Safety Evaluation
◽
Potential Treatment
◽
Antibody Drug Conjugate
◽
Site Specific
◽
Receptor Alpha
◽
Drug Conjugate
◽
Endometrial Cancers
◽
A Site
◽
Antibody Drug
Download Full-text
Abstract 742: Nonclinical safety evaluation of STRO-001, a site-specific anti-CD74 antibody-drug conjugate for the potential treatment of B-cell malignancies
10.1158/1538-7445.am2018-742
◽
2018
◽
Author(s):
Willy Solis
◽
Venita De Almeida
◽
Abigail Yu
◽
Maureen Bruhns
◽
James Zawada
◽
...
Keyword(s):
B Cell
◽
Safety Evaluation
◽
Potential Treatment
◽
Antibody Drug Conjugate
◽
B Cell Malignancies
◽
Site Specific
◽
Drug Conjugate
◽
A Site
◽
Antibody Drug
Download Full-text
In Vitro and In Vivo Activity of IMGN853, an Antibody–Drug Conjugate Targeting Folate Receptor Alpha Linked to DM4, in Biologically Aggressive Endometrial Cancers
Molecular Cancer Therapeutics
◽
10.1158/1535-7163.mct-17-0930
◽
2018
◽
Vol 17
(5)
◽
pp. 1003-1011
◽
Cited By ~ 10
Author(s):
Gary Altwerger
◽
Elena Bonazzoli
◽
Stefania Bellone
◽
Tomomi Egawa-Takata
◽
Gulden Menderes
◽
...
Keyword(s):
Folate Receptor
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Endometrial Cancers
◽
Antibody Drug
Download Full-text
Remarkable in vitro and in vivo activity of IMGN853, an antibody-drug conjugate targeting folate receptor alpha linked to the tubulin-disrupting maytansinoid DM4, in biologically aggressive (type II) endometrial cancers
Gynecologic Oncology
◽
10.1016/j.ygyno.2018.04.159
◽
2018
◽
Vol 149
◽
pp. 70
Author(s):
G. Altwerger
◽
E. Bonazzoli
◽
S. Bellone
◽
T. Takata
◽
G. Menderes
◽
...
Keyword(s):
Folate Receptor
◽
Type Ii
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Endometrial Cancers
◽
Antibody Drug
Download Full-text
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202, a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
Case Medical Research
◽
10.31525/ct1-nct04300556
◽
2020
◽
Author(s):
Keyword(s):
Folate Receptor
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Tumor Types
◽
Antibody Drug
Download Full-text
FORWARD I (GOG 3011): A phase III study of mirvetuximab soravtansine, a folate receptor alpha (FRa)-targeting antibody-drug conjugate (ADC), versus chemotherapy in patients (pts) with platinum-resistant ovarian cancer (PROC)
Annals of Oncology
◽
10.1093/annonc/mdz250
◽
2019
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Vol 30
◽
pp. v403
◽
Cited By ~ 8
Author(s):
K. Moore
◽
A. Oza
◽
N. Colombo
◽
A. Oaknin
◽
G. Scambia
◽
...
Keyword(s):
Ovarian Cancer
◽
Folate Receptor
◽
Phase Iii
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Platinum Resistant
◽
Phase Iii Study
◽
Antibody Drug
Download Full-text
Abstract 1770: Morab-202, a folate receptor alpha-targeted antibody-drug conjugate, shows a highly potent activity against a panel of FRA-expressing tumors
10.1158/1538-7445.am2018-1770
◽
2018
◽
Author(s):
Caroline Mignard
◽
Coralie DURIX
◽
Katherine Rybinski
◽
Xin Cheng
◽
Keiji Furuuchi
◽
...
Keyword(s):
Folate Receptor
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Antibody Drug
Download Full-text
Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models
Neoplasia
◽
10.1016/j.neo.2016.11.002
◽
2016
◽
Vol 18
(12)
◽
pp. 775-784
◽
Cited By ~ 29
Author(s):
Jose F. Ponte
◽
Olga Ab
◽
Leanne Lanieri
◽
Jenny Lee
◽
Jennifer Coccia
◽
...
Keyword(s):
Ovarian Cancer
◽
Folate Receptor
◽
Standard Of Care
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Cancer Models
◽
Antibody Drug
Download Full-text
Relationship of pharmacokinetics (PK), toxicity, and initial evidence of clinical activity with IMGN853, a folate receptor alpha (FRa) targeting antibody drug conjugate in patients (Pts) with epithelial ovarian cancer (EOC) and other FRa-positive solid tumors.
Journal of Clinical Oncology
◽
10.1200/jco.2014.32.15_suppl.5571
◽
2014
◽
Vol 32
(15_suppl)
◽
pp. 5571-5571
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Cited By ~ 4
Author(s):
Kathleen N. Moore
◽
Joseph Ponte
◽
Patricia LoRusso
◽
Michael J. Birrer
◽
Todd Michael Bauer
◽
...
Keyword(s):
Ovarian Cancer
◽
Epithelial Ovarian Cancer
◽
Solid Tumors
◽
Folate Receptor
◽
Clinical Activity
◽
Antibody Drug Conjugate
◽
Receptor Alpha
◽
Drug Conjugate
◽
Relationship Of
◽
Antibody Drug
Download Full-text
Safety Profile of Mirvetuximab Soravtansine, a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, in Patients with Recurrent Ovarian Cancer
Gynecologic Oncology
◽
10.1016/j.ygyno.2019.11.066
◽
2020
◽
Vol 156
(3)
◽
pp. e15-e16
Author(s):
Kathleen G. Essel
◽
Lainie P. Martin
◽
David M. O’Malley
◽
Ursula Matulonis
◽
Jason A. Konner
◽
...
Keyword(s):
Ovarian Cancer
◽
Safety Profile
◽
Folate Receptor
◽
Recurrent Ovarian Cancer
◽
Antibody Drug Conjugate
◽
Folate Receptor Alpha
◽
Receptor Alpha
◽
Drug Conjugate
◽
Antibody Drug
Download Full-text
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