Abstract 1455: Design of ONCR-177 base vector, a next generation oncolytic herpes simplex virus type-1, optimized for robust oncolysis, transgene expression and tumor-selective replication

2019 ◽  
Author(s):  
Edward M. Kennedy ◽  
Terry Farkaly ◽  
Prajna Behera ◽  
Allison Colthart ◽  
Caitlin Goshert ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Transgene Expression ◽  
Oncolytic Herpes Simplex Virus ◽  
Base Vector ◽  
Simplex Virus ◽  
Tumor Selective

778 ENHANCED EFFICACY OF ONCOLYTIC HERPES SIMPLEX VIRUS TYPE 1 (HSV-1) ARMED WITH IL-12 IN BLADDER CANCER MODELS

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Hiroshi Fukuhara ◽  
Jiangang Hou ◽  
Yuzuri Tsurumaki ◽  
Yukio Homma ◽  
Yasushi Ino ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Cancer Models ◽  
Oncolytic Herpes Simplex Virus ◽  
Simplex Virus ◽  
Hsv 1

scholarly journals Oncolytic Herpes Simplex Virus Type-1 Therapy in a Highly Infiltrative Animal Model of Human Glioblastoma

2008 ◽  
Vol 14 (5) ◽  
pp. 1571-1580 ◽  
Author(s):  
Peter C. Huszthy ◽  
Dorota Goplen ◽  
Frits Thorsen ◽  
Heike Immervoll ◽  
Jian Wang ◽  
...  
Keyword(s):  
Animal Model ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Human Glioblastoma ◽  
Oncolytic Herpes Simplex Virus ◽  
Simplex Virus

Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors

2010 ◽  
Vol 12 (7) ◽  
pp. 613-623 ◽  
Author(s):  
Arturo R. Maldonado ◽  
Chuck Klanke ◽  
Anil G. Jegga ◽  
Bruce J. Aronow ◽  
Yonatan Y. Mahller ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Molecular Engineering ◽  
Oncolytic Herpes Simplex Virus ◽  
Simplex Virus
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