Mechanisms of Drug Sensitization to TRA-8, an Agonistic Death Receptor 5 Antibody, Involve Modulation of the Intrinsic Apoptotic Pathway in Human Breast Cancer Cells

Hope M. Amm; Tong Zhou; Adam D. Steg; Huichien Kuo; Yufeng Li; Donald J. Buchsbaum

doi:10.1158/1541-7786.mcr-10-0133

Mechanisms of Drug Sensitization to TRA-8, an Agonistic Death Receptor 5 Antibody, Involve Modulation of the Intrinsic Apoptotic Pathway in Human Breast Cancer Cells

Molecular Cancer Research ◽

10.1158/1541-7786.mcr-10-0133 ◽

2011 ◽

Vol 9 (4) ◽

pp. 403-417 ◽

Cited By ~ 23

Author(s):

Hope M. Amm ◽

Tong Zhou ◽

Adam D. Steg ◽

Huichien Kuo ◽

Yufeng Li ◽

...

Keyword(s):

Breast Cancer ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Death Receptor ◽

Death Receptor 5 ◽

Intrinsic Apoptotic Pathway ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway ◽

Drug Sensitization

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Combined Low Doses of PPARγ and RXR Ligands Trigger an Intrinsic Apoptotic Pathway in Human Breast Cancer Cells

American Journal Of Pathology ◽

10.2353/ajpath.2009.081078 ◽

2009 ◽

Vol 175 (3) ◽

pp. 1270-1280 ◽

Cited By ~ 46

Author(s):

Daniela Bonofiglio ◽

Erika Cione ◽

Hongyan Qi ◽

Attilio Pingitore ◽

Mariarita Perri ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Low Doses ◽

Intrinsic Apoptotic Pathway ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway

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RRR-γ-tocopherol induces human breast cancer cells to undergo apoptosis via death receptor 5 (DR5)-mediated apoptotic signaling

Cancer Letters ◽

10.1016/j.canlet.2007.10.008 ◽

2008 ◽

Vol 259 (2) ◽

pp. 165-176 ◽

Cited By ~ 24

Author(s):

Weiping Yu ◽

Sook-Kyung Park ◽

Li Jia ◽

Richa Tiwary ◽

Wenjun W. Scott ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Death Receptor ◽

Death Receptor 5 ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Signaling

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Differential anti-tumor activity of coriolus versicolor (Yunzhi) extract through p53- and/or Bcl-2-dependent apoptotic pathway in human breast cancer cells

Cancer Biology & Therapy ◽

10.4161/cbt.4.6.1721 ◽

2005 ◽

Vol 4 (6) ◽

pp. 638-644 ◽

Cited By ~ 21

Author(s):

Cheong-Yip Ho ◽

Chi-Fai Kim ◽

Kwok-Nam Leung ◽

Fung Kwok-Pui ◽

Tak-Fu Tse ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Coriolus Versicolor ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway ◽

Anti Tumor Activity

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Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxel-induced apoptotic pathway of MCF-7 human breast cancer cells

International Journal of Molecular Medicine ◽

10.3892/ijmm.2011.617 ◽

2011 ◽

Vol 27 (4) ◽

Cited By ~ 1

Author(s):

Sato

Keyword(s):

Breast Cancer ◽

Transcription Factors ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway ◽

Basic Helix Loop Helix ◽

Helix Loop Helix ◽

Mcf 7

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Investigation of the apoptotic pathway induced by benzimidazole–oxindole conjugates against human breast cancer cells MCF-7

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.05.045 ◽

2016 ◽

Vol 26 (14) ◽

pp. 3313-3317 ◽

Cited By ~ 7

Author(s):

Vadithe Lakshma Nayak ◽

Bobburi Nagaseshadri ◽

M.V.P.S. Vishnuvardhan ◽

Ahmed Kamal

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway ◽

Mcf 7

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α-TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway

Molecular Carcinogenesis ◽

10.1002/mc.20681 ◽

2010 ◽

Vol 49 (11) ◽

pp. 964-973 ◽

Cited By ~ 13

Author(s):

Weiping Yu ◽

Richa Tiwary ◽

Jing Li ◽

Sook-Kyung Park ◽

Li Jia ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Death Receptor ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Death Receptor Pathway

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Insulin-Like Growth Factor-Binding Protein 3 Induces Caspase-Dependent Apoptosis through a Death Receptor-Mediated Pathway in MCF-7 Human Breast Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-03-1675 ◽

2004 ◽

Vol 64 (6) ◽

pp. 2229-2237 ◽

Cited By ~ 66

Author(s):

Ho-Seong Kim ◽

Angela R. Ingermann ◽

Junko Tsubaki ◽

Stephen M. Twigg ◽

Gillian E. Walker ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Death Receptor ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Factor Binding ◽

Mcf 7

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Berberine-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway

Tumor Biology ◽

10.1007/s13277-014-2754-7 ◽

2014 ◽

Vol 36 (2) ◽

pp. 1279-1288 ◽

Cited By ~ 33

Author(s):

Juan Xie ◽

Yinyan Xu ◽

Xinyan Huang ◽

Yanni Chen ◽

Jing Fu ◽

...

Keyword(s):

Breast Cancer ◽

Reactive Oxygen Species ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Reactive Oxygen Species Generation ◽

Oxygen Species ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptotic Pathway ◽

Induced Apoptosis

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Dual Inhibition of Focal Adhesion Kinase and Epidermal Growth Factor Receptor Pathways Cooperatively Induces Death Receptor-mediated Apoptosis in Human Breast Cancer Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m205002200 ◽

2002 ◽

Vol 277 (41) ◽

pp. 38978-38987 ◽

Cited By ~ 90

Author(s):

Vita Golubovskaya ◽

Lucia Beviglia ◽

Li-Hui Xu ◽

H. Shelton Earp ◽

Rolf Craven ◽

...

Keyword(s):

Breast Cancer ◽

Focal Adhesion ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Death Receptor ◽

Growth Factor Receptor ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Epidermal Growth ◽

Dual Inhibition

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Antiproliferative and apoptotic activities of extracts from carob tree (Ceratonia siliqua L.) in MDA-MB-231 human breast cancer cells

Planta Medica ◽

10.1055/s-0028-1084046 ◽

2008 ◽

Vol 74 (09) ◽

Author(s):

L Custódio ◽

E Fernandes ◽

AL Escapa ◽

S López-Avilés ◽

A Fajardo ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Ceratonia Siliqua ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Carob Tree ◽

Ceratonia Siliqua L

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