Electrical Stimulation of the Auditory Pathway in Deaf Patients Following Acoustic Neurinoma Surgery and Initial Results with a New Auditory Brainstem Implant System

Author(s):  
J. Mueller ◽  
R. Behr ◽  
C. Knaus ◽  
C. Milewski ◽  
F. Schoen ◽  
...  
1995 ◽  
Vol 109 (5) ◽  
pp. 385-389 ◽  
Author(s):  
R. Laszig ◽  
W. P. Sollmann ◽  
N. Marangos

AbstractCentral electrical stimulation of the auditory pathway can allow hearing in patients sufferingfrom deafness localized in the auditory nerve. Developments in a multi-channel auditory brainstem implant based on the Nucleus Mini 22 Cochlear implant with transcutaneous signal transmission is discussed. The devices have been implanted in nine European patients suffering from Neurofibromatosis Type 2. Preliminary speech perception results and patient satisfaction are encouraging, and the data presented include some limited open speech recognition.


2002 ◽  
Vol 11 (2) ◽  
pp. 128-133 ◽  
Author(s):  
Kim B. Jackson ◽  
Gerhard Mark ◽  
Jan Helms ◽  
Joachim Mueller ◽  
Robert Behr

Neurofibromastosis type II (NF2) is a condition that may result in bilateral acoustic neuromas. The tumors and their removal may cause profound bilateral deafness. Because the auditory nerve is compromised, people with NF2 are unable to receive a cochlear implant to restore a sensation of hearing. Electrical stimulation of the auditory pathway can provide hearing in such people. This is possible by means of an auditory brainstem implant (ABI). This article focuses on the MED-EL highrate multichannel ABI system. The system consists of the implanted and external components. Appropriate placement of the ABI is dependent on electrical auditory brainstem response testing performed intra-operatively. Data on a group of European patients implanted with the MED-EL ABI are presented. Results are promising and include some open-set speech ability.


1987 ◽  
Vol 96 (4) ◽  
pp. 349-361 ◽  
Author(s):  
Mark J. Maslan ◽  
Josef M. Miller

As a result of practical considerations, histopathologic findings of the temporal bone in humans with cochlear prosthesis implants have been limited. This project attempts to better define safe parameters of electrical stimulation of the inner ear and compare the safe limits of intracochlear vs. extracochlear stimulation sites. Guinea pigs were implanted with single electrodes either on the promontory or in the scala tympani and were stimulated relative to a remote indifferent for 12 hours distributed over a 4-week period. Electrical auditory brainstem evoked responses (EABRs) were tested before and after each of four 3-hour stimulation sessions. Six weeks after implantation, the animals were killed, and their cochleas were examined under the scanning electron microscope. Intracochlear electrodes exhibited thresholds for damage well below one half of that found for most extracochlear stimulation sites. The function-relating damage threshold (in amperes) to frequency of intracochlear stimulation is represented by two straight lines, with an intercept of 1 kHz. The low-frequency limb exhibited a slope of 3 to 4 dB/octave, whereas the high-frequency limb exhibited a slope of 9 to 10 dB/octave. Extracochlear results were too variable to permit speculation. Changes in EABRs were only variably related to histopathologic findings.


ORL ◽  
1995 ◽  
Vol 57 (6) ◽  
pp. 305-309 ◽  
Author(s):  
Mattheus W. Vischer ◽  
Victoria Bajo-Lorenzana ◽  
JinSheng Zhang ◽  
Rudolf Häusler ◽  
Eric M. Rouiller

1973 ◽  
Vol 38 (3) ◽  
pp. 320-325 ◽  
Author(s):  
Ronald R. Tasker ◽  
L. W. Organ

✓ Auditory hallucinations were produced by electrical stimulation of the human upper brain stem during stereotaxic operations. The responses were confined to stimulation of the inferior colliculus, brachium of the inferior colliculus, medial geniculate body, and auditory radiations. Anatomical confirmation of an auditory site was obtained in one patient. The hallucination produced was a low-pitched nonspecific auditory “paresthesia” independent of the structure stimulated, the conditions of stimulation, or sonotopic factors. The effect was identical to that reported from stimulating the primary auditory cortex, and virtually all responses were contralateral. These observations have led to the following generalizations concerning electrical stimulation of the somesthetic, auditory, vestibular, and visual pathways within the human brain stem: the hallucination induced in each is the response to comparable conditions of stimulation, is nonspecific, independent of stimulation site, confined to the primary pathway concerned, chiefly contralateral, and identical to that induced by stimulating the corresponding primary auditory cortex. No sensory responses are found in the brain stem corresponding to those from the sensory association cortex.


1999 ◽  
Vol 78 (2) ◽  
pp. 110-117 ◽  
Author(s):  
Roland Laszig ◽  
Nicolas Marangos ◽  
Wolf-Peter Sollmann ◽  
Richard T. Ramsden

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