Gene Expression of KA Type and NMDA Receptors and of a Glycine Transporter in the Rat Pineal Gland

1993 ◽  
Vol 58 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Kohji Sato ◽  
Hiroshi Kiyama ◽  
Shoichi Shimada ◽  
Masaya Tohyama
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Nmda Receptors ◽  
Glycine Transporter ◽  
Rat Pineal Gland

Daily rhythm and regulation of clock gene expression in the rat pineal gland

2004 ◽  
Vol 120 (2) ◽  
pp. 164-172 ◽  
Author(s):  
V Simonneaux ◽  
V.-J Poirel ◽  
M.-L Garidou ◽  
D Nguyen ◽  
E Diaz-Rodriguez ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Clock Gene ◽  
Daily Rhythm ◽  
Clock Gene Expression ◽  
Rat Pineal Gland

Circannual Somatostatin Gene and Somatostatin Receptor Gene Expression in the Early Post-Natal Rat Pineal Gland

1997 ◽  
Vol 66 (5) ◽  
pp. 368-374 ◽  
Author(s):  
Eugenia Mato ◽  
Pilar Santisteban ◽  
Julie A. Chowen ◽  
Oscar Fornas ◽  
Martijn Bouwens ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Receptor Gene ◽  
Somatostatin Receptor ◽  
Rat Pineal Gland ◽  
Receptor Gene Expression

CircRNA-WNK2 acts as a ceRNA for miR-328a-3p to promote AANAT expression in the male rat pineal gland

Endocrinology ◽  
2021 ◽  
Author(s):  
Yi Zheng ◽  
Hao-Qi Wang ◽  
Hai-Xiang Guo ◽  
Heng-Li Xie ◽  
Wei-Di Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Circadian Rhythm ◽  
Pineal Gland ◽  
Rat Model ◽  
Noncoding Rnas ◽  
Luciferase Reporter ◽  
Male Rat ◽  
Biological Functions ◽  
Melatonin Secretion ◽  
Rat Pineal Gland

Abstract Noncoding RNAs (ncRNAs), including miRNAs and circRNAs, which are expressed with a daily rhythm in the rat pineal gland, are associated with the regulation of melatonin secretion and other biological functions. However, the mechanisms of these molecules in the rat pineal gland are not yet fully understood. In this study, we found circR-WNK2 was highly expressed at night, which may be involved in the regulation of melatonin secretion through the ceRNA mechanism. By dual luciferase reporter, RNA pulldown, and FISH assays, we found that miR-328a-3p can target circR-WNK2 and the Aa-nat mRNA 3’UTR. Transfection experiments indicated that circR-WNK2 could competitively bind to miR-328a-3p, reduce miR-328a-3p expression, and promote Aa-nat gene expression and melatonin secretion. And by constructing an SCGx rat model, we found that ncRNAs expressed in the pineal gland was regulated by signals from the SCN. This finding supports the hypothesis that these noncoding RNAs may interact to shape the circadian rhythm through transcriptional processing in melatonin synthesis.

scholarly journals Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night

2018 ◽  
Vol Volume 10 ◽  
pp. 203-215 ◽  
Author(s):  
Daniela Meneses-Santos ◽  
Daniella do Carmo Buonfiglio ◽  
Rodrigo Antonio Peliciari-Garcia ◽  
Angela Maria Ramos-Lobo ◽  
Divanízia do Nascimento Souza ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Clock Gene ◽  
Chronic Treatment ◽  
Melatonin Synthesis ◽  
Clock Gene Expression ◽  
Rat Pineal Gland

Ontogenesis of hydroxyindole-O-methyltransferase gene expression and activity in the rat pineal gland

1998 ◽  
Vol 110 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Christophe Ribelayga ◽  
François Gauer ◽  
Paul Pévet ◽  
Valérie Simonneaux
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Methyltransferase Gene ◽  
Rat Pineal Gland ◽  
Expression And Activity

scholarly journals Analysis of daily and circadian gene expression in the rat pineal gland

2008 ◽  
Vol 60 (2) ◽  
pp. 192-198 ◽  
Author(s):  
Chiaki Fukuhara ◽  
Gianluca Tosini
Keyword(s):  
Gene Expression ◽  
Pineal Gland ◽  
Circadian Gene ◽  
Rat Pineal Gland

scholarly journals Cognitive deficits and changes in gene expression of NMDA receptors after prenatal methylmercury exposure.

2002 ◽  
Vol 110 (suppl 5) ◽  
pp. 855-858 ◽  
Author(s):  
Mario Baraldi ◽  
Paola Zanoli ◽  
Fabio Tascedda ◽  
Joan M C Blom ◽  
Nicoletta Brunello
Keyword(s):  
Gene Expression ◽  
Nmda Receptors ◽  
Cognitive Deficits ◽  
Methylmercury Exposure
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