scholarly journals When a Case Is Not a Case: Effects of Phenotype Misclassification on Power and Sample Size Requirements for the Transmission Disequilibrium Test with Affected Child Trios

2009 ◽  
Vol 67 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Steven Buyske ◽  
Guang Yang ◽  
Tara C. Matise ◽  
Derek Gordon
Keyword(s):  
Sample Size ◽  
Transmission Disequilibrium Test ◽  
Transmission Disequilibrium ◽  
Affected Child

scholarly journals Power approximation of the transmission disequilibrium test

2012 ◽  
Vol 53 ◽  
Author(s):  
Šarūnas Germanas ◽  
Audronė Jakaitienė
Keyword(s):  
Sample Size ◽  
Poisson Distribution ◽  
Transmission Disequilibrium Test ◽  
Normal Approximation ◽  
Poisson Approximation ◽  
Transmission Disequilibrium ◽  
Power Approximation ◽  
Allele Transmission

In this paper we apply Poisson distribution in order to approximate the power of the Transmission Disequilibrium Test (TDT). In this research we calculated the power of the TDT for different values of sample size n and different values of allele transmission frequencies p. The research showed that Poisson approximation have smaller errors than Normal approximation when the power is between 0.8 and 0.95 and sample size m is equal or bigger than 50.

Transmission Disequilibrium Test Power and Sample Size in the Presence of Locus Heterogeneity

2009 ◽  
Vol 8 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Chuanwen Chen ◽  
Guang Yang ◽  
Steven Buyske ◽  
Tara Matise ◽  
Stephen J Finch ◽  
...  
Keyword(s):  
Sample Size ◽  
Transmission Disequilibrium Test ◽  
Test Power ◽  
Locus Heterogeneity ◽  
Transmission Disequilibrium

scholarly journals Analytic power and sample size calculation for the genotypic transmission/disequilibrium test in case-parent trio studies

2014 ◽  
Vol 56 (6) ◽  
pp. 1076-1092 ◽  
Author(s):  
Christoph Neumann ◽  
Margaret A. Taub ◽  
Samuel G. Younkin ◽  
Terri H. Beaty ◽  
Ingo Ruczinski ◽  
...  
Keyword(s):  
Sample Size ◽  
Transmission Disequilibrium Test ◽  
Sample Size Calculation ◽  
Transmission Disequilibrium

scholarly journals Rare-Variant Extensions of the Transmission Disequilibrium Test: Application to Autism Exome Sequence Data

2014 ◽  
Vol 94 (1) ◽  
pp. 33-46 ◽  
Author(s):  
Zongxiao He ◽  
Brian J. O’Roak ◽  
Joshua D. Smith ◽  
Gao Wang ◽  
Stanley Hooker ◽  
...  
Keyword(s):  
Rare Variant ◽  
Transmission Disequilibrium Test ◽  
Sequence Data ◽  
Transmission Disequilibrium ◽  
Exome Sequence Data ◽  
Test Application ◽  
Exome Sequence

An entropy-based genome-wide transmission/disequilibrium test

2007 ◽  
Vol 121 (3-4) ◽  
pp. 357-367 ◽  
Author(s):  
Jinying Zhao ◽  
Eric Boerwinkle ◽  
Momiao Xiong
Keyword(s):  
Transmission Disequilibrium Test ◽  
Transmission Disequilibrium ◽  
Genome Wide
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