Characterization of Vincristine-Resistant HOB1 Lymphoma Cell Line Showing the Classical MDR Phenotype and Altered Expression of Membrane Glycoproteins

Oncology ◽  
1994 ◽  
Vol 51 (1) ◽  
pp. 2-8 ◽  
Author(s):  
Wei-Ping Lee ◽  
Chao-Lin Lee
1998 ◽  
Vol 149 (1) ◽  
pp. 41 ◽  
Author(s):  
Hidehiko Kawai ◽  
Yukika Kitamura ◽  
Osamu Nikaido ◽  
Masaaki Tatsuka ◽  
Hiroko Hama-Inaba ◽  
...  

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Christine Kleinert ◽  
Matthieu Blanchet ◽  
François Gagné ◽  
Michel Fournier

The determination of changes in gene expression profiles with xenobiotic dose will allow identifying biomarkers and modes of toxicant action. The harbor seal (Phoca vitulina) 11B7501 B lymphoma cell line was exposed to 1, 10, 100, 1000, 10,000, or 25,000 μg/L 17α-ethinyl estradiol (EE2, the active compound of the contraceptive pill) for 24 h. Following exposure, RNA was extracted and transformed into cDNA. Transcript expression in exposed vs. control lymphocytes was analyzed via RT-qPCR to identify genes with altered expression. Our analysis indicates that gene expression for all but the reference gene varied with dose, suggesting that different doses induce distinct physiological responses. These findings demonstrate that RT-qPCR could be used to identify immunotoxicity and relative dose in harbor seal leukocytes.


2020 ◽  
Vol 59 (9) ◽  
pp. 517-524
Author(s):  
Kiyotaka Izumi ◽  
Momoko Nishikori ◽  
Hepei Yuan ◽  
Yasuyuki Otsuka ◽  
Kensuke Nakao ◽  
...  

2020 ◽  
Vol 390 (2) ◽  
pp. 111986
Author(s):  
Michael C. Rahe ◽  
Cheryl M.T. Dvorak ◽  
Barry Wiseman ◽  
Daniel Martin ◽  
Michael P. Murtaugh

1998 ◽  
Vol 62 (3) ◽  
pp. 209-219 ◽  
Author(s):  
Hideyuki Onodera ◽  
Naotaka Ishiguro ◽  
Motohiro Horiuchi ◽  
Morikazu Shinagawa

2015 ◽  
Vol 96 (2) ◽  
pp. 144-151
Author(s):  
Kiyotaka Kawauchi ◽  
Toshie Ogasawara ◽  
Motohiko Aiba ◽  
Mariko Fujibayashi ◽  
Tsutomu Sanaka ◽  
...  

2002 ◽  
Vol 43 (1) ◽  
pp. 165-172 ◽  
Author(s):  
Hartmut Merz ◽  
Karin Lange ◽  
Timo Gaiser ◽  
Anke Müller ◽  
Ursula Kapp ◽  
...  

Oncotarget ◽  
2015 ◽  
Vol 6 (35) ◽  
pp. 37229-37240 ◽  
Author(s):  
Valentina Restelli ◽  
Rosaria Chilà ◽  
Monica Lupi ◽  
Andrea Rinaldi ◽  
Ivo Kwee ◽  
...  

2014 ◽  
Vol 24 (1) ◽  
pp. 60-62 ◽  
Author(s):  
John Boudjarane ◽  
Arnaud Essaydi ◽  
Laure Farnault ◽  
Cornel Popovici ◽  
Marina Lafage-Pochitaloff ◽  
...  

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