Inhibition of IgE-Mediated N-Acetylglucosaminidase and Serotonin Release from Rat Basophilic Leukemia Cells (RBL-2H3) by Tenidap: A Novel Anti-Inflammatory Agent

1990 ◽  
Vol 91 (4) ◽  
pp. 369-373 ◽  
Author(s):  
Maryrose J. Conklyn ◽  
Saul B. Kadin ◽  
Henry J. Showell
Keyword(s):  
Serotonin Release ◽  
Leukemia Cells ◽  
Inflammatory Agent ◽  
Rat Basophilic Leukemia Cells ◽  
Ige Mediated ◽  
Anti Inflammatory ◽  
Basophilic Leukemia

Effects of Various Cytochalasins on the IgE-Mediated Serotonin Release from Rat Basophilic Leukemia Cells

1985 ◽  
Vol 78 (3) ◽  
pp. 237-242 ◽  
Author(s):  
Reiko Teshima ◽  
Hideharu Ikebuchi ◽  
Setsuko Sekita ◽  
Shinsaku Natori ◽  
Tadao Terao
Keyword(s):  
Serotonin Release ◽  
Leukemia Cells ◽  
Rat Basophilic Leukemia Cells ◽  
Ige Mediated ◽  
Basophilic Leukemia

Effects of inhibitors of arachidonic acid metabolism on serotonin release from rat basophilic leukemia cells

1993 ◽  
Vol 25 (2) ◽  
pp. 131-144 ◽  
Author(s):  
Yasushi Igarashi ◽  
Jens D. Lundgren ◽  
James H. Shelhamer ◽  
Michael A. Kaliner ◽  
Martha V. White
Keyword(s):  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Serotonin Release ◽  
Leukemia Cells ◽  
Rat Basophilic Leukemia Cells ◽  
Basophilic Leukemia

scholarly journals Effects of Synthetic Food Colors on (3H)Serotonin Release from Rat Basophilic Leukemia Cells (RBL-2H3).

Eisei kagaku ◽  
1995 ◽  
Vol 41 (3) ◽  
pp. 206-211 ◽  
Author(s):  
YUKIO TANAKA ◽  
YOSHIMASA KONISHI ◽  
TAKAHIRO NISHIMUNE ◽  
YUTAKA TAKAGAKI
Keyword(s):  
Serotonin Release ◽  
Leukemia Cells ◽  
Rat Basophilic Leukemia Cells ◽  
Basophilic Leukemia ◽  
Food Colors

Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells

1981 ◽  
Vol 212 (2) ◽  
pp. 572-580 ◽  
Author(s):  
Anne Mc Givney ◽  
Yutaka Morita ◽  
Fulton T. Crews ◽  
Fusao Hirata ◽  
Julius Axelrod ◽  
...  
Keyword(s):  
Leukemia Cells ◽  
Ionophore A23187 ◽  
Rat Basophilic Leukemia Cells ◽  
Ige Mediated ◽  
Basophilic Leukemia

scholarly journals IgE-mediated chemotaxis of rat basophilic leukemia cells towards specific antigen.

1983 ◽  
Vol 157 (6) ◽  
pp. 2166-2171 ◽  
Author(s):  
N Orida ◽  
J D Feldman ◽  
D H Katz ◽  
F T Liu
Keyword(s):  
Bovine Serum Albumin ◽  
Specific Antigen ◽  
Specific Ige ◽  
Leukemia Cells ◽  
Boyden Chamber ◽  
Antigen Specificity ◽  
Rat Basophilic Leukemia Cells ◽  
Ige Mediated ◽  
Basophilic Leukemia

We evaluated chemotactic properties of four sublines of rat basophilic leukemia cells using blindwell Boyden chamber assays. After sensitization with a mouse monoclonal IgE directed against dinitrophenyl (DNP), cells from sublines 2H3-C and 926a underwent chemotaxis toward DNP-bovine serum albumin (BSA) and sublines RBL-1 and 4A did not. Chemotactic responses required specific IgE and were determined by the IgE antigen specificity used for sensitization. The threshold for chemotaxis was on the order of 10(-10) M DNP-BSA. Release of incorporated [3H]-serotonin did not always parallel chemotactic responses, which suggests that chemotaxis and secretion may be two unlinked processes that occur during basophil activation. Our results predict a possible in vivo mechanism whereby specific chemotactic responses of basophils and other FcR epsilon-bearing cells are mediated via specific IgE bound to membrane FcR epsilon.

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