Controlled Prospective Study of Oral Ciprofloxacin versus Amoxycillin/Clavulanic Acid in Chronic Suppurative Otitis Media in Adults

Chemotherapy ◽  
1994 ◽  
Vol 40 (1) ◽  
pp. 16-23 ◽  
Author(s):  
F. Legent ◽  
Ph. Bordure ◽  
C. Beauvillain ◽  
P. Berche
1992 ◽  
Vol 101 (10) ◽  
pp. 866-869 ◽  
Author(s):  
Dan M. Fliss ◽  
Naftali Meidan ◽  
Ron Dagan ◽  
Alberto Leiberman

Medical management of chronic suppurative otitis media without cholesteatoma in children was shown recently to be efficacious. We undertook a prospective study in order to determine 1) the organisms associated with the disease and their sensitivity to various antibiotics and 2) their association with clinical variables. Pseudomonas was isolated from 84% of the patients, enteric gram-negative bacilli from 32%, Staphylococcus aureus from 20%, streptococci from 14%, and Hemophilus influenzae from 15%. Pseudomonas aeruginosa was the sole isolate in 48 of the 128 patients (38%). The sensitivity of P aeruginosa (78 isolates) was 100% (of isolates) to mezlocillin and ciprofloxacin, 99% to tobramycin and ceftazidime, 97% to piperacillin, 94% to gentamicin, and 78% to ceftriaxone. The isolated organisms and their sensitivity to antibiotics were not associated with age, sex, duration of otorrhea, or the presence of granulation tissue or polyps. We believe that our data may contribute to the appropriate choice of antibiotics when nonsurgical management of chronic suppurative otitis media without cholesteatoma is considered.


2015 ◽  
Vol 129 (8) ◽  
pp. 779-783 ◽  
Author(s):  
N N Nwokoye ◽  
L O Egwari ◽  
O O Olubi

AbstractBackground:Otitis media is a more frequent occurrence in children, and the disease may progress from an acute to chronic state if appropriate and timely intervention is not initiated.Methods:A total of 212 children aged 6 months to 10 years were examined and treated for otitis media, in a 13-month hospital-based study.Results:Acute otitis media was diagnosed in 130 (61.3 per cent) of the patients. There were 82 (38.7 per cent) chronic suppurative otitis media cases. The incidence of acute otitis media and chronic suppurative otitis media in the first year of life was 54.6 per cent and 45.1 per cent respectively. Chronic suppurative otitis media patients were assigned to one of three treatment groups. Recovery occurred in 70.4 per cent of amoxicillin-treated patients, in 88.9 per cent of amoxicillin-clavulanic acid treated patients and in 96.4 per cent of culture and antibiotic sensitivity test patients. Relapses were seen only in the amoxicillin (five cases) and amoxicillin-clavulanic acid (two cases) groups.Conclusion:The success rate in patients treated with antibiotics makes this option mandatory for an established diagnosis.


2019 ◽  
Vol 6 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Rushika Patel ◽  
Sumeet Kaur Ghai ◽  
Shreeya V. Kulkarni ◽  
Chaitanya Bharadwaj ◽  
Vandana Sancheti ◽  
...  

2016 ◽  
Vol 3 (102) ◽  
pp. 5645-5649
Author(s):  
Sami Ullah ◽  
Faiz S. M ◽  
Mohd Shakeel ◽  
Saurabh Srivastav ◽  
Satveer Singh Jassal ◽  
...  

1992 ◽  
Vol 11 (11) ◽  
pp. 925-929 ◽  
Author(s):  
RUTH LANG ◽  
SIVAN GOSHEN ◽  
ANNICK RAAS-ROTHSCHILD ◽  
ARYEH RAZ ◽  
DOV OPHIR ◽  
...  

2019 ◽  
Vol 10 (1) ◽  
pp. 01-05
Author(s):  
Chethan Kumar G ◽  
◽  
Kiren T ◽  
Gopakumar . ◽  
Adhavan E ◽  
...  

2019 ◽  
Vol 4 (1) ◽  
pp. 19-25
Author(s):  
Dr. Ganesh Bala Arivazhagan ◽  
◽  
Dr. Sriram Govindaraj ◽  
Dr.Harishvel V ◽  
Dr. Ganesh Babu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document