<i>N</i>-Acetylcysteine Reverses Mitochondrial Dysfunctions and Behavioral Abnormalities in 3-Nitropropionic Acid-Induced Huntington’s Disease

Rajat Sandhir; Aditi Sood; Arpit Mehrotra; Sukhdev S. Kamboj

doi:10.1159/000334273

N-Acetylcysteine Reverses Mitochondrial Dysfunctions and Behavioral Abnormalities in 3-Nitropropionic Acid-Induced Huntington’s Disease

Neurodegenerative Diseases ◽

10.1159/000334273 ◽

2012 ◽

Vol 9 (3) ◽

pp. 145-157 ◽

Cited By ~ 52

Author(s):

Rajat Sandhir ◽

Aditi Sood ◽

Arpit Mehrotra ◽

Sukhdev S. Kamboj

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Mitochondrial Dysfunctions ◽

Nitropropionic Acid ◽

Behavioral Abnormalities ◽

3 Nitropropionic Acid

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Quercetin supplementation is effective in improving mitochondrial dysfunctions induced by 3-nitropropionic acid: Implications in Huntington's disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ◽

10.1016/j.bbadis.2012.11.018 ◽

2013 ◽

Vol 1832 (3) ◽

pp. 421-430 ◽

Cited By ~ 61

Author(s):

Rajat Sandhir ◽

Arpit Mehrotra

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Mitochondrial Dysfunctions ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Pre-clinical studies on beneficial effect of quercetin supplementation in improving mitochondrial dysfunctions induced by 3-nitropropionic acid: Implications in Huntington's disease

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2012.06.216 ◽

2012 ◽

Vol 1817 ◽

pp. S79

Author(s):

Arpit Mehrotra ◽

Rajat Sandhir

Keyword(s):

Beneficial Effect ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Clinical Studies ◽

Mitochondrial Dysfunctions ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Mitochondrial toxin 3-nitropropionic acid produces startle reflex abnormalities and striatal damage in rats that model some features of Huntington's disease

Neuroscience Letters ◽

10.1016/s0304-3940(97)00482-5 ◽

1997 ◽

Vol 231 (2) ◽

pp. 103-107 ◽

Cited By ~ 39

Author(s):

M.H Kodsi ◽

N.R Swerdlow

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Startle Reflex ◽

Nitropropionic Acid ◽

Mitochondrial Toxin ◽

3 Nitropropionic Acid

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Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: Possible behavioural, biochemical and cellular alterations

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.04.058 ◽

2009 ◽

Vol 615 (1-3) ◽

pp. 91-101 ◽

Cited By ~ 26

Author(s):

Puneet Kumar ◽

Anil Kumar

Keyword(s):

Protective Effect ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid ◽

Cellular Alterations

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P2-044: Neuroprotective role of progesterone against 3-nitropropionic-acid-induced Huntington's disease-like symptoms in rats

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.686 ◽

2013 ◽

Vol 9 ◽

pp. P360-P360

Author(s):

Puneet Kumar ◽

Pushpender Kumar ◽

Rahul Deshmukh ◽

PL Sharma

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2018.06.079 ◽

2018 ◽

Vol 105 ◽

pp. 1254-1268 ◽

Cited By ~ 7

Author(s):

Ravi Chandra Sekhara Reddy Danduga ◽

Subba Reddy Dondapati ◽

Phani Kumar Kola ◽

Lilly Grace ◽

Rahil Vandana Bisky Tadigiri ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Neuroprotective Activity ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Thymoquinone loaded solid lipid nanoparticles counteracts 3-Nitropropionic acid induced motor impairments and neuroinflammation in rat model of Huntington’s disease

Metabolic Brain Disease ◽

10.1007/s11011-018-0252-0 ◽

2018 ◽

Vol 33 (5) ◽

pp. 1459-1470 ◽

Cited By ~ 4

Author(s):

Surekha Ramachandran ◽

Sumathi Thangarajan

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Rat Model ◽

Solid Lipid Nanoparticles ◽

Lipid Nanoparticles ◽

Motor Impairments ◽

Solid Lipid ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Dopamine Modulates the Susceptibility of Striatal Neurons to 3-Nitropropionic Acid in the Rat Model of Huntington’s Disease

Journal of Neuroscience ◽

10.1523/jneurosci.18-23-10116.1998 ◽

1998 ◽

Vol 18 (23) ◽

pp. 10116-10127 ◽

Cited By ~ 81

Author(s):

David S. Reynolds ◽

Rebecca J. Carter ◽

A. Jennifer Morton

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Rat Model ◽

Striatal Neurons ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Chronic 3-Nitropropionic Acid Treatment in Baboons Replicates the Cognitive and Motor Deficits of Huntington’s Disease

Journal of Neuroscience ◽

10.1523/jneurosci.16-09-03019.1996 ◽

1996 ◽

Vol 16 (9) ◽

pp. 3019-3025 ◽

Cited By ~ 189

Author(s):

Stéphane Palfi ◽

Robert J. Ferrante ◽

Emmanuel Brouillet ◽

M. Flint Beal ◽

Robert Dolan ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Acid Treatment ◽

Motor Deficits ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington’s Disease

Journal of Huntington s Disease ◽

10.3233/jhd-160189 ◽

2016 ◽

Vol 5 (1) ◽

pp. 19-32 ◽

Cited By ~ 10

Author(s):

Elizabeth A. Skillings ◽

A. Jennifer Morton

Keyword(s):

Mouse Model ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Cognitive Deficits ◽

Repeat Length ◽

Cag Repeat ◽

Delayed Onset ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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