Results of Intracavitary Chemotherapy with Mitoxantrone

2015 ◽  
pp. 180-183
Author(s):  
W. Hoffmann ◽  
F. Migeod ◽  
M. Kress ◽  
S. Seeber

2012 ◽  
pp. 123-150 ◽  
Author(s):  
Gianfranco Baronzio ◽  
Giammaria Fiorentini ◽  
Marco Ballerini ◽  
Valter Cassuti ◽  
Giorgio Forzenigo ◽  
...  




1994 ◽  
Vol 83 (3) ◽  
pp. 429-432 ◽  
Author(s):  
Etienne Chatelut ◽  
Peter Suh ◽  
Sinil Kim


1996 ◽  
Vol 82 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Marco Colleoni ◽  
Francesco Sartori ◽  
Francesco Calabrò ◽  
Patrizia Nelli ◽  
Giovanni Vicario ◽  
...  

Aims and background Malignant mesothelioma is associated with a median survival of 4 to 12 months. Data from the literature indicate that single modality treatment (surgery or intrapleural and/or systemic chemotherapy) does not significantly affect survival. Methods We therefore evaluated a combined approach consisting of surgery (pleurectomy + diaphragmatic or pericardial resection), intrapleural chemotherapy with cisplatin (100 mg/m2) and cytarabine (1,000 mg/m2) for 4 h immediately after pleurectomy, and systemic chemotherapy consisting of epirubicin (60 mg/m2) and mitomycin-C (10 mg/m2) day 1 every 4 weeks for 4 cycles. Results Twenty patients were enrolled in the study and were evaluable. Thirteen cases had residual gross disease after pleurectomy and 7 patients only minimal disease. Median time to disease progression was 7.4 months, and median survival was 11.5 months (range, 2-25+). No treatment-related death have been observed. Side effects after intracavitary chemotherapy included renal toxicity, anaemia and pain. Myelosuppression and alopecia were recorded during systemic chemotherapy. Conclusions The results of the study indicate that the schedule is feasible, with encouraging results in terms of survival for patients with minimal residual disease after surgery.



2007 ◽  
Vol 38 (3/4) ◽  
pp. 63-68
Author(s):  
Teruo ITOH ◽  
Kazuyuki UCHIDA ◽  
Atsuko KOJIMOTO ◽  
Ayako IKEDA ◽  
Kazumi NIBE ◽  
...  




1985 ◽  
Vol 3 (3) ◽  
pp. 205-233 ◽  
Author(s):  
Maurie Markman ◽  
Franco M. Muggia


2005 ◽  
Vol 77 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Michael C. Park ◽  
Charles E. Weaver Jr ◽  
John E. Donahue ◽  
Prakash Sampath


1999 ◽  
Vol 141 (5) ◽  
pp. 547-549 ◽  
Author(s):  
A. Savas ◽  
E. Arasıl ◽  
F. Batay ◽  
M. Selcuki ◽  
Y. Kanpolat


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