scholarly journals Gastric Schwannoma Mimicking Malignant Gastrointestinal Stromal Tumor Exhibiting Increased Fluorodeoxyglucose Uptake

2016 ◽  
Vol 9 (1) ◽  
pp. 228-234 ◽  
Author(s):  
Sung Jin Oh ◽  
Byoung Jo Suh ◽  
Jong Kwon Park
Keyword(s):  
Gastric Neoplasms ◽  
Emission Computed Tomography ◽  
Computed Tomography Imaging ◽  
Mesenchymal Tumors ◽  
Tomography Imaging ◽  
Submucosal Tumors ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Positron Emission ◽  
Fluorine 18 Fluorodeoxyglucose

A schwannoma is a kind of neurogenic tumor that rarely occurs in the gastrointestinal tract. Gastric schwannomas make up 0.2% of all gastric neoplasms. Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors and up to 60-70% of GIST occur in the stomach. Schwannoma and GIST are similar in clinical features, so they are difficult to differentiate preoperatively. Differential diagnosis of these two submucosal tumors is important because of the malignant potential of GIST and the relatively benign course of gastric schwannomas. We report a 49-year-old woman who was diagnosed after operation with a gastric schwannoma, which was suspected a malignant GIST by fluorine-18-fluorodeoxyglucose positron emission computed tomography imaging.

scholarly journals Pancreatic GIST in a Patient with Limited Stage Small Cell Lung Cancer: A Case Report and Review of Published Cases

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Minh Phan ◽  
Shari Jones ◽  
Justin Jenkins ◽  
Shubham Pant ◽  
Mohamad Khawandanah
Keyword(s):  
Kinase Inhibitor ◽  
Needle Aspiration ◽  
Small Cell ◽  
African American Female ◽  
Small Cell Lung ◽  
Computed Tomography Imaging ◽  
Mesenchymal Tumors ◽  
Tomography Imaging ◽  
Stromal Tumors ◽  
Limited Stage

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and usually occur in the stomach and the small intestine. The pancreas is an extremely rare primary site for GISTs and there are 25 reported cases of pancreatic GIST with most being treated with surgical resection. We describe a 52-year-old African-American female who was diagnosed with limited stage small cell carcinoma in November 2009 and treated with concurrent cisplatin/etoposide chemotherapy and radiation. She subsequently achieved complete remission. Two years later she was diagnosed with localized pancreatic GIST by endoscopic ultrasonography guided fine needle aspiration. We treated her with a tyrosine kinase inhibitor (TKI) imatinib 400 mg oral dose daily as she declined surgery. Her disease is stable based on computed tomography imaging scans 40 months after diagnosis without any metastasis. To the best of our knowledge, our case is the second case of localized pancreatic GIST treated with TKI monotherapy.

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