scholarly journals Isolated Bilateral Gastrocnemius Myositis in Crohn Disease Successfully Treated with Adalimumab

2016 ◽  
Vol 10 (3) ◽  
pp. 661-667 ◽  
Author(s):  
Salvatore Vadala di Prampero ◽  
Marco Marino ◽  
Francesco Toso ◽  
Claudio Avellini ◽  
Vu Nguyen ◽  
...  

Extraintestinal manifestations are common in inflammatory bowel disease; however, muscular involvement in Crohn disease is rarely reported. We present a case of a 26-year-old male with ileocolonic Crohn disease who developed sudden tenderness in both calves. Doppler ultrasound was negative for deep vein thrombosis. Magnetic resonance imaging of the gastrocnemius muscle showed high intensity signal in the muscle fibers, and muscle biopsy demonstrated nonspecific lymphocytic myositis. Other relevant laboratory results included normal antineutrophil cytoplasmic antibodies and creatine kinase as well as elevated C-reactive protein, erythrocyte sedimentation rate, and anti-Saccharomyces cerevisiae IgG titer. The patient was in clinical remission, being treated with azathioprine 2.5 mg/kg. Prednisone 60 mg/day was initiated with rapid resolution of calf tenderness; however, tenderness soon returned when the dose was tapered to 10 mg/day. Subsequently, prednisone and azathioprine were discontinued, and adalimumab was started at standard induction and maintenance doses. The patient’s symptoms resolved shortly after the first induction dose. A repeat magnetic resonance imaging of the calves – 3 months after starting adalimumab – showed complete resolution of muscle inflammation. To our knowledge, this is the first case of gastrocnemius myositis – a rare extraintestinal manifestation of Crohn disease – successfully treated with anti-tumor necrosis factor agents.

1989 ◽  
Vol 30 (4) ◽  
pp. 445-446 ◽  
Author(s):  
Charles W. Francis ◽  
T. H. Foster ◽  
S. Totterman ◽  
B. Brenner ◽  
V. J. Marder ◽  
...  

2019 ◽  
Vol 32 (4) ◽  
pp. 273-276 ◽  
Author(s):  
David J Ritchie ◽  
Charles Q Li ◽  
Reid Hoshide ◽  
Daniel Vinocur

Gadolinium (Gd)-enhanced magnetic resonance imaging plays an essential role in the detection, characterization, and staging of intracranial neoplasms and vascular abnormalities. Although Gd is helpful in a majority of situations, it can lead to diagnostic misinterpretation in the setting of active vascular extravasation. Scarce reports of intracranial extravasation of Gd are present in the literature. Here, we report the first case of surgically proven spontaneous intraparenchymal extravasation of Gd mimicking an enhancing intra-axial neoplasm in a pediatric patient. Early and accurate recognition of Gd extravasation is critical in obtaining the accurate diagnosis and triaging patients expeditiously into proper avenues of care.


1996 ◽  
Vol 82 (6) ◽  
pp. 610-613 ◽  
Author(s):  
Angeles Rovirosa ◽  
Joan Berenguer ◽  
Alberto Sánchez-Reyes ◽  
Carlos Arias ◽  
Jordi Ferre ◽  
...  

We present the case of a large maxillary hemangioma treated by radiotherapy. Only 4 cases managed by radiotherapy have been reported in the literature, and most authors negate the radiosensitivity of the tumor. In our patient, the outcome was excellent; by 6 months tumor reduction was more than 50%. This is the first case referred to in the literature whose radiotherapy response was evaluated by magnetic resonance imaging. We describe the clinical and imaging findings of this very rare tumor and its evolution. We also comment on the literature reviewed.


2020 ◽  
pp. 014556132097261
Author(s):  
Kyeong Suk Park ◽  
Bong-Jin Shin ◽  
Chul Ho Jang

Hypertrophic pachymeningitis (HP) is defined by inflammation and thickening of the dura mater, and the etiologic factors are idiopathic or secondary to various conditions. To date, HP in the internal auditory canal (IAC) has rarely been reported. There have only been 3 reports of HP in the IAC. Magnetic resonance imaging showed enhancement of along the IAC and vestibule. After antibiotic treatment, enhancement was reduced with visible seventh and eighth nerves. The patient underwent tympanomastoidectomy. To our knowledge, this is the first case of HP associated with a labyrinth fistula complicated by cholesteatoma. We report MRI image with literatures.


2018 ◽  
Vol 20 (2) ◽  
pp. 68-71
Author(s):  
Naoko Kamiya ◽  
Shuji Hatakeyama ◽  
Naoki Kanda ◽  
Sho Yonaha ◽  
Dai Akine ◽  
...  

2017 ◽  
Vol 08 (02) ◽  
pp. 277-280 ◽  
Author(s):  
Kamble Jayaprakash Harsha ◽  
Jeevan S. Nair

ABSTRACTTurner syndrome (TS) is a rare genetic disease due to the absence of one X chromosome. Patients with TS have more subtle neurological/neuropsychiatric problems, while headache is an uncommon clinical presentation which needs attention. We report a 12-year-old child presenting with typical cough headache. Her magnetic resonance imaging revealed Chiari I malformation associated with TS. To the best of our knowledge, Chiari I malformation associated with TS is not described in literature. We report the first case of TS associated with Chiari I malformation. Interestingly, Chiari I malformation is also associated with Noonan’s syndrome, which is a close morphological mimicker of TS, raising the possibility of sharing similar pathogenesis in both conditions.


Sign in / Sign up

Export Citation Format

Share Document