scholarly journals Invasive Pulmonary Adenocarcinoma with Lepidic Growth Pattern in a Pregnant Patient

2018 ◽  
Vol 11 (3) ◽  
pp. 822-834
Author(s):  
Omar Jiménez-Zarazúa ◽  
Lourdes N. Vélez-Ramírez ◽  
José C. Padilla–López ◽  
Juana R. García-Ramírez ◽  
Pedro L. González–Carillo ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Growth Pattern ◽  
Specific Treatment ◽  
Pregnant Patient ◽  
Pulmonary Adenocarcinoma ◽  
Reproductive Age ◽  
Lepidic Growth ◽  
Pulmonary Neoplasia

Among the differential diagnoses that should be considered in acute respiratory failure (ARF) are infectious processes, autoimmune diseases, interstitial pulmonary fibrosis, and pulmonary neoplasia. Timely diagnosis of lung neoplasia is complicated in the early stages. An opportune diagnosis, as well as the specific treatment, decrease mortality. ARF occurs 1 in 500 pregnancies and is most common during the postpartum period. Among the specific etiologies that cause ARF during pregnancy that must be considered are: (1) preeclampsia; (2) embolism of amniotic fluid; (3) peripartum cardiomyopathy; and (4) trophoblastic embolism. The case of a 36-year-old patient with a 33-week pregnancy and ARF is presented. The patient presented dyspnea while exerting moderate effort that progressed to orthopnea and type 1 respiratory insufficiency. Imaging studies showed bilateral alveolar infiltrates and predominantly right areas of consolidation. Blood cultures, a galactomannan assay and IgG antibodies against mycoplasma pneumoniae, were reported as negative. Autoimmune etiology was ruled out through an immunoassay. A percutaneous pulmonary biopsy was performed and an invasive pulmonary adenocarcinoma with lepidic growth pattern (i.e. lepidic pulmonary adenocarcinoma, LPA) result was reported. This etiology is rare and very difficult to recognize in acute respiratory failure cases. After infectious, autoimmune and interstitial lung fibrosis have been excluded the clinician must suspect of lung cancer in a patient with acute respiratory failure and chest imaging compatible with the presence of ground-glass nodular opacities, a solitary nodule or mass with bronchogram, and lung consolidation. In the presence of acute respiratory failure, the suspicion of pulmonary neoplasia in an adult of reproductive age must be timely. Failure to recognize this etiology can lead to fatal results.

Acute respiratory failure

2020 ◽  
pp. 3867-3880
Author(s):  
Susannah Leaver ◽  
Jeremy Cordingley ◽  
Simon Finney ◽  
Mark Griffiths
Keyword(s):  
Respiratory Failure ◽  
Critical Illness ◽  
Acute Respiratory Failure ◽  
Critically Ill ◽  
System Failures ◽  
Life Saving ◽  
Delayed Recognition ◽  
Covert Infection

Acute respiratory failure is defined clinically by hypoxaemia with (type 2) or without (type 1) hypercapnia. It is one of the most common problems afflicting critically ill patients and is a common indication for transfer to an intensive care unit. Critical illness may be manifest solely as respiratory insufficiency, especially in patients with covert infection. Acute respiratory failure frequently coexists with other organ system failures in the critically ill, and delayed recognition of the condition adversely affects outcome. The signs of critical illness tend to be similar whatever the precipitating cause and are manifest in failure of the respiratory, cardiovascular, and neurological systems. Full and repeated physical examination may be required to assess the cause and severity of acute respiratory failure and its associated complications, but in severe cases should not delay the instigation of life-saving support and treatment.

scholarly journals Etiology, Clinical Profile and Outcome of Acute Respiratory Failure in Adults in Kashmir Valley (North India): A Hospital Based Prospective Study

2020 ◽  
Vol 5 (09) ◽  
pp. 407-411
Author(s):  
Dr. Abdul Ahad Wani ◽  
Dr. Manzoor Ahmad ◽  
Dr. Amir Shafi ◽  
Dr. Muzaffar Naik ◽  
Dr. Tariq Bhat ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Respiratory Distress ◽  
Prospective Study ◽  
Acute Exacerbation ◽  
North India ◽  
Respiratory Pattern ◽  
Kashmir Valley

Background: A prospective study to evaluate the etiological factors, clinical features, treatment modalities and outcome of acute respiratory failure in adults (> 18 years age) in Kashmir valley north India is important to understand the epidemiological trends and the detailed disease manifestations. Methods: We conducted a hospital based prospective study which was conducted over a period of one and half year, initiated in January 2018 and concluded in 2019 in tertiary care hospital. 100 patients above the age of 18 years with acute respiratory failure were actively enrolled. Acute respiratory failure was identified by the defined criteria, in any patient presenting with respiratory arrest / respiratory failure/respiratory distress with SPO2 ≤92%, breathlessness of <2 weeks duration and altered respiratory pattern. The patients who fulfilled at least one of the following criteria of respiratory failure were included in the study. (I)Arterial PaO2<70mmHg, (II)Peripheral O2 saturation ≤92% breathing in room air (III) Arterial PaCO2 ≥45mmHg (IV) PH ≤7.35 with signs and symptoms of respiratory distress. Results: Of the total of 100 patients included in the study, the mean age of the cohort was 55 SD ± 19 years. The cause of respiratory failure were COPD with acute exacerbation (45%), sepsis with MODS (20%), acute O.P. poisoning (12%), massive ICH (4%), acute liver failure with respiratory failure(3%), ARDS(3%),acute opioid poisoning with respiratory failure (3%), acute LVF (2%),PTE (2%), anaphylaxis (2%), acute M.I. (1%), myasthenia crisis (2%) strangulation with asphyxia (1%) and fat embolism (1%). Type-2 respiratory failure was found in 45% while type-1 respiratory failure was found in 55% patients. 55 % patients needed invasive ventilation; 26% patients needed NIV. While 19% patients needed high flow oxygen with nasal cannula. Conclusion: Commonest cause of acute respiratory failure in adults is COPD with acute exacerbation (45%) followed by sepsis with MODS (20%). Type 2 respiratory failure accounted for 45% while type 1 accounted for 55% of acute respiratory failure in adults. In our study, COPD is the leading cause of death in acute respiratory failure followed by sepsis with MODS.

scholarly journals Arnold-Chiari Malformation Type 1 as an Unusual Cause of Acute Respiratory Failure: A Case Report

Authorea ◽  
2020 ◽  
Author(s):  
Mohamad Khatib ◽  
Moustafa Elshafei ◽  
Amr Shabana ◽  
Dnyaneshwar Mutkule ◽  
Dinesh Chengamaraju ◽  
...  
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Chiari Malformation ◽  
Arnold Chiari Malformation ◽  
Chiari Malformation Type 1

scholarly journals Arnold‐Chiari malformation type 1 as an unusual cause of acute respiratory failure: A case report

2020 ◽  
Vol 8 (10) ◽  
pp. 1943-1946
Author(s):  
Mohamad Y. Khatib ◽  
Moustafa S. Elshafei ◽  
Amr M. Shabana ◽  
Dnyaneshwar P. Mutkule ◽  
Dinesh Chengamaraju ◽  
...  
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Chiari Malformation ◽  
Arnold Chiari Malformation ◽  
Chiari Malformation Type 1

scholarly journals ĐẶC ĐIỂM LÂM SÀNG, NGUYÊN NHÂN, PHÂN LOẠI SUY HÔ HẤP CẤP Ở TRẺ EM THEO KHÍ MÁU

2018 ◽  
Vol 34 (2) ◽  
Author(s):  
Phạm Văn Đếm
Keyword(s):  
Intensive Care Unit ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Clinical Feature ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Arterial Blood

SUMMARY THE CLINICAL FEATURE, CAUSES AND CLASSIFICATION OF PEDIATRIC ACUTE RESPIRATORY FAILURE THROUGH ARTERIAL BLOOD GAS Pham Thi Que, Pham Van Thang Ha Noi Medical University   Objectives: The study to describe clinical feature, causes and classification of acute respiratory failure in children through arterial blood gas in the Intensive Care Unit of Vietnam National Children's Hospital. Subjects and Methods: Aprospective descriptive study on 96 patients with acute respiratory failure in the Intensive Care Unit in Vietnam of National Children's Hospital from 10/2016 to 10/2017. Results: Type 2 acute respiratory failure was 55,2%, followed by type 1 with 25% and type 3 with 19,8%. Total patients with type 1 respiratory failure had tachypnea, cyanosis and SpO2 ˂ 90% and bilateral parenchymal lung injury. Type 2 acute respiratory failure can have symptoms like brachypnea, acynosis, SpO2 ≥ 90%. Wheezing is most common; emphysema and atelectasis with 37,2%. Bronchopneumonia is the most common cause of acute respiratory failure, including 61,1% type 2 acute respiratory failure. Conclusion: Based on the clinical feature of acute respiratory failure as a basis for assessing severe condition and appropriate treatment interventions. Key words: classification of acute respiratory failure, arterial blood gas.  

Acute respiratory failure

2010 ◽  
pp. 3132-3146 ◽  
Author(s):  
Susannah Leaver ◽  
Timothy Evans
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Respiratory Failure ◽  
Intensive Care Unit Admission ◽  
Acute Respiratory Failure ◽  
Normal Range ◽  
Common Problems

Acute respiratory failure is defined clinically by hypoxaemia (PaO2 <8 kPa, normal range 10–13.3 kPa) with (type 2) or without (type 1) hypercapnia (PaCO2 >6.5 kPa). It is one of the most common problems afflicting the severely ill patient and often necessitates intensive care unit admission....

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