scholarly journals A Case of Pneumatic Displacement with Gas Tamponade Performed for Macular Subretinal Hemorrhage Complicating Vogt-Koyanagi-Harada Disease

2020 ◽  
Vol 11 (1) ◽  
pp. 143-150 ◽  
Author(s):  
Takatoshi Kobayashi ◽  
Masanori Fukumoto ◽  
Nanae Takai ◽  
Kohichi Maruyama ◽  
Rei Tada ◽  
...  
Keyword(s):  
Retinal Pigment Epithelial ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Serous Retinal Detachment ◽  
Gas Injection ◽  
Subretinal Hemorrhage ◽  
Retinal Pigment Epithelial Detachment ◽  
Gas Tamponade ◽  
Pneumatic Displacement ◽  
Intravitreal Gas

We experienced a case of subretinal hemorrhage (SRH) from choroidal neovascularization (CNV) complicating Vogt-Koyanagi-Harada disease (VKH) that underwent pneumatic displacement of hematoma by intravitreal gas injection. A 76-year-old male revealed VKH relapses and optical coherence tomography showed irregular retinal pigment epithelium in his right eye and serous retinal detachment and retinal pigment epithelial detachment in his left eye. Fluorescein angiography of the left eye showed hyperfluorescence possibly attributable to CNV. One month later, SRH occurred in the left eye, yet it was spontaneously absorbed. However, approximately 1 year later, the SRH recurred in the left eye affecting a wide area, including the macular region, and his visual acuity (VA) decreased to 0.06. When pneumatic displacement of the hematoma by intravitreal gas injection was performed, the SRH was inferiorly displaced, and his VA improved to 0.4. Pneumatic displacement with gas tamponade was effective for treating a case of SRH caused by persistent CNV complicating VKH.

scholarly journals Outcomes of Retinal Pigment Epithelial Detachment in Vogt-Koyanagi-Harada Disease

2022 ◽  
Author(s):  
Xiaomin Zhang ◽  
Chuanzhen Zheng ◽  
Kaixuan Wang ◽  
Kailei Guo ◽  
Qingqin Tao ◽  
...  
Keyword(s):  
Retinal Pigment Epithelial ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Subsequent Development ◽  
Corticosteroid Treatment ◽  
Pigment Epithelial Detachment ◽  
Retinal Pigment Epithelial Detachment ◽  
Pigment Epithelial ◽  
Corrected Visual Acuity ◽  
Edge Points

Abstract IntroductionThe aim of this study was to report the clinical profile and outcomes of retinal pigment epithelial detachment (PED) in Vogt-Koyanagi-Harada (VKH) disease, and to evaluate the correlation between PED and the subsequent development of central serous chorioretinopathy (CSC) throughout the whole corticosteroid treatment course.materials and methodsA total of 470 eyes with VKH were reviewed, and 12 eyes with VKH and PED were recruited. Patients were divided into two groups according to the CSC onset or not throughout the whole course (CSC group and non-CSC group). Best-corrected visual acuity (BCVA) improvement, and PED angle (PEDA, the angle between the two lines of the vertex of the lifted retinal pigment epithelium to the two edge points of the Bruch membrane) were compared between the two groups.ResultsThe prevalence of PED and CSC in VKH was 2.55% (12/470) and 1.06% (5/470), respectively. BCVA improvement in the non-CSC group was greater than that in the CSC group, but without a statistical difference (P=0.25). PEDA was significantly smaller in the CSC group than in the non-CSC group (P=0.03).DiscussionPEDA is an ideal parameter to reflect hydrostatic pressure and stretches for RPE. As PED predisposes to the development of CSC in selected VKH eyes, PEDA may be a valuable predictive factor for the development of CSC in VKH patients.

scholarly journals Prechoroidal Cleft in Type 3 Neovascularization: Incidence, Timing, and Its Association with Visual Outcome

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Jae Hui Kim ◽  
Young Suk Chang ◽  
Jong Woo Kim ◽  
Chul Gu Kim ◽  
Dong Won Lee
Keyword(s):  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Visual Outcome ◽  
Subretinal Hemorrhage ◽  
Type 3 Neovascularization ◽  
The Difference ◽  
Type 3 ◽  
Endothelial Growth Factor ◽  
Rpe Tear

Purpose. To investigate the incidence and timing of prechoroidal cleft development and its association with visual prognosis in type 3 neovascularization. Methods. This retrospective study included 166 eyes that were diagnosed with type 3 neovascularization. All eyes were treated with antivascular endothelial growth factor therapy. The incidence and timing of prechoroidal cleft development were evaluated. Best-corrected visual acuity (BCVA) at diagnosis and at final follow-up was compared between eyes with (cleft group) and without (no-cleft group) prechoroidal cleft. The incidence of retinal pigment epithelium (RPE) tear and subretinal hemorrhage was also compared between the two groups. Results. During the mean 39.7 ± 18.5 months of follow-up, prechoroidal cleft developed in 37 eyes (22.3%) at an average of 14.6 ± 10.4 months. The BCVA at final follow-up was significantly worse in the cleft group than in the no-cleft group (P=0.024), whereas the difference was not significant at diagnosis (P=0.969). The incidence of RPE tear (P=0.002) and subretinal hemorrhage (P<0.001) was significantly higher in the cleft group. Conclusions. Prechoroidal cleft is a frequently observed finding during the treatment course of type 3 neovascularization. Eyes with prechoroidal cleft are at high risk of RPE tear or subretinal hemorrhage and subsequently associated with poor prognosis.

scholarly journals Effect of systemic bevacizumab therapy on retinal pigment epithelial detachment

2006 ◽  
Vol 91 (6) ◽  
pp. 785-789 ◽  
Author(s):  
M. Bolz ◽  
S. Michels ◽  
W. Geitzenauer ◽  
F. Prager ◽  
U. Schmidt-Erfurth
Keyword(s):  
Retinal Pigment Epithelial ◽  
Retinal Pigment ◽  
Pigment Epithelial Detachment ◽  
Retinal Pigment Epithelial Detachment ◽  
Pigment Epithelial
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