scholarly journals Pyogenic Liver Abscess Secondary to Sigmoid Diverticulitis: An Unusual Presentation

2020 ◽  
Vol 14 (1) ◽  
pp. 165-171
Author(s):  
Edward Paul Joseph Muscat

Pyogenic liver abscesses, despite being a rare complication of diverticulitis and inflammatory bowel disease, are potentially serious life-threatening pathologies. Diverticular diseases can lead to disruption of the colonic mucosal barrier and can serve as a route for bacterial infection via the portal venous system. This patient had such a delayed presentation due to his atypical symptoms; he developed large abscess formation, detected by computed tomography, eventually requiring an ultrasound-guided drain followed by a colonoscopy. The present report describes an elderly gentleman who developed a bacterial liver abscess due to seeding of a commensal organism caused by sigmoid diverticulitis.

2019 ◽  
Vol 1 (3) ◽  
pp. 15-17
Author(s):  
Sabbah M ◽  
Trad D ◽  
Jemmali C ◽  
Jouini R ◽  
Elloumi H ◽  
...  

Intestinal tuberculosis diagnosis is often difficult because of non-specific symptoms, miming many other conditions such as malignancy, infectious disease, and inflammatory bowel disease. Free intestinal perforation is an uncommon but life-threatening complication of intestinal tuberculosis, associated with high morbidity and mortality.


2017 ◽  
Vol 9 (2) ◽  
pp. 7-12
Author(s):  
Hari Bahadur KC ◽  
S Bhuju ◽  
R R Dhakal ◽  
D S Timilsina

Background: Although liver abscess is a potentially life threatening disease, early diagnosis and prompt treatment has resulted good clinical outcome. The epidemiology and management of this condition have evolved over time.Objective: To study our experience in clinical characteristics and management of liver abscess in a tertiary hospital over a period of three years.Methods: The hospital records of all patients discharged with the diagnosis of liver abscess from September 2010 to March 2013 were reviewed. The demographics, clinical presentation, investigation tools, method of treatment and outcome were recorded and analyzed.Results: Total of 17 patients of liver abscess were admitted during this period, of which, 13 were pyogenic and four amebic. The median age was 50 (7 - 75) years with male to female ratio of 1.42 : 1. Age group 40 - 60 years was most commonly affected. Single lesions were found in 11 (64.7%) and multiple in six (35.3%) patients. The most common presentation was fever and abdominal pain/tenderness. Jaundice was seen in five (29.4%) patients and abnormal liver function test in 10 (58.8%) patients. Commonest route of infection among pyogenic liver abscess were through biliary tree pathology (Five patients) and via portal venous system (Three patients). Pus and blood culture were positive in six (46.15%) and four (30.76%) patients respectively, and E. coli was the commonest pathogen isolated. Patients were treated with anti-microbial therapy and interventional radiology techniques: Nine patients with percutaneous needle aspiration, four with percutaneous drainage. Antibiotics alone were sufficient in three patients and open surgical drainage was required in one patient. There was one case of mortality where the abscess was associated with diabetes mellitus. Conclusion: Liver abscess is a potentially life threatening disease and commonly associated with underlying gastrointestinal pathology. Adequate antibiotic coverage and image guided intervention is optimal first-line treatment with favorable outcome.Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December  2016, Page: 7-12


2016 ◽  
Vol 111 ◽  
pp. S855-S856
Author(s):  
Aeden Bernice Timbol ◽  
Karen Mondragon ◽  
Virgilio Banez

Author(s):  
Durgesh Gowda ◽  
Vasant Shenoy ◽  
Usman Malabu ◽  
Donald Cameron ◽  
Kunwarjit Sangla

Summary Our patient had drainage of a large amoebic liver abscess. This got complicated by a severe degree of hypotension, which required aggressive fluid resuscitation and hydrocortisone support. Computerised tomography (CT) of the abdomen revealed bilateral adrenal gland haemorrhage (BAH) resulting in primary adrenal gland failure, which was the cause for hypotension. Patient was on long-term warfarin for provoked deep vein thrombosis of lower limb, which was discontinued before the procedure. Thrombophilia profile indicated the presence of lupus anticoagulant factor with prolonged activated partial thromboplastin time (aPTT). Patient was discharged on lifelong warfarin. This case emphasises the need for strong clinical suspicion for diagnosing BAH, rare but life-threatening condition, and its association with amoebic liver abscess and anti-phospholipid antibody syndrome (APLS). Learning points Recognition of BAH as a rare complication of sepsis. APLS can rarely cause BAH.


2016 ◽  
Vol 53 (3) ◽  
pp. 270-275 ◽  
Author(s):  
D. Antolová ◽  
D. Hudáčková ◽  
M. Fecková ◽  
A. Feketeová ◽  
M. Szilágyová

SummaryPyogenic liver abscess is an uncommon but important and potentially life-threatening disease that occurs whenever there is failure of clearance of an infection in the liver. Work presents a rare case of pyogenic liver abscess with confirmed bacterial aetiology ofStaphylococcus aureus, subsequently confirmedEchinococcus multilocularisand suspectedMycobacterium tuberculosisliver infection in 6 years old child. Moreover, several other parasitic diseases were recorded. According to clinical presentation of diseases, it could be supposed that liver impairment caused by alveolar echinococcosis and potentially also byM. tuberculosiscould be the predisposition site for the capture ofStaphylococcus aureusin altered liver tissues during its haematogenous spreading, and thus contributed to the development and subsequent clinical presentation of pyogenic liver abscess. The presence of three different aetiological agents complicated the diagnostic process as well as the therapy of the patient and made her prognosis uncertain. Proper diagnosis of multiloculated liver abscesses, with echinococcosis and hepatic tuberculosis considered in the differential diagnosis, is therefore crucial to administration of early and appropriate treatment.


2020 ◽  
Vol 7 (12) ◽  
pp. 4190-4196
Author(s):  
Nadia Bashir ◽  
Muhammad Adnan Shereen ◽  
Abeer Kazmi ◽  
Muhammad Sajid ◽  
Hafiz Ullah

Background: Pyogenic liver abscess (PLA) is a rare but life-threatening disease, with a frequency ranging from 10.83 to 17.45 per 100,000 persons. The major cause of PLA is bacterial infection of liver parenchyma. The present research study was designed to investigate the common microbes causing PLA in Peshawar (Pakistan) and to evaluate a variety of the most capable and efficient antibiotics for treatment of PLA. Methods: A 7-year (2012 - 2018) retrospective demographic study of medical records of all PLA patients (n = 379) admitted to the Hayatabad Medical Complex (HMC) and Khyber Teaching Hospital (KTH) was initially performed. The demographic study was followed by biochemical tests and antibiotic resistivity tests of microorganisms, isolated from available samples and selected from literature using web services. Results & Conclusion: The demographic data revealed that 70% of the PLA patients were under the age of 50, with male predominance (male to female ratio of 3:1). It was concluded that K. pneumonia, poly-microbes (K. pneumonia and Citrobacter), and E. coli are the most common microbes involved in causing PLA in the population of Peshawar. E.coli, Citrobacter and K. pneumonia were sensitive to Cefixime and Ciprofloxacin (100% sensitivity rate), but showed significant resistance against Amoxycillin, Oxacillin and Fusidic Acid. It is, therefore, prudent to practice susceptibility-directed antibiotic therapy.


1960 ◽  
Vol 38 (2) ◽  
pp. 262-266 ◽  
Author(s):  
Richard Knowles ◽  
Joseph A. Rinaldo

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