Clinical and Morphological Spectrum of Histoplasmosis on Cytology Along with the Review of Literature

2020 ◽  
Vol 64 (6) ◽  
pp. 532-538
Author(s):  
Gargi Kapatia ◽  
Ashmita Saha ◽  
Manish Rohilla ◽  
Parikshaa Gupta ◽  
Nalini Gupta ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Review Of Literature ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology ◽  
Male To Female

<b><i>Objective:</i></b> The aim of the study was to study the clinical and morphological spectrum of histoplasmosis diagnosed by fine needle aspiration cytology (FNAC). <b><i>Study Design:</i></b> A total of 17 patients diagnosed with histoplasmosis on FNAC were studied over a period of 5 years. The cytology smears were studied and analysed for the cytomorphological spectrum of histoplasmosis. <b><i>Results:</i></b> Among the 17 patients studied, the mean age was 51.3 years (range 6–84 years). Male-to-female ratio was 3.25:1 with 4 females and 13 males. The frequent sites of involvement were the lung (5), lymph node (4), adrenal gland (4), and skin (4). The most common cytological patterns were histiocytic collection, followed by granulomas and multinucleated giant cells. Necrosis was noted in only 4 cases. <b><i>Conclusion:</i></b> Fine needle aspiration is a highly accurate, rapid, and cheap technique for the diagnosis of histoplasmosis due to its distinct morphological features.

Aspiration Cytology of Pediatric Solitary Papillary Hyperplastic Thyroid Nodule

2001 ◽  
Vol 125 (12) ◽  
pp. 1575-1578 ◽  
Author(s):  
Kamal K. Khurana ◽  
Zubair W. Baloch ◽  
Virginia A. LiVolsi
Keyword(s):  
Fine Needle Aspiration ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Cytokeratin 19 ◽  
Intranuclear Inclusions ◽  
Cytologic Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
False Positive Diagnosis ◽  
Needle Aspiration Cytology

Abstract Context.—Solitary papillary hyperplastic thyroid nodules (SPHTNs) are frequently encountered in children and teenagers. Although the histologic features are well described, to the best of our knowledge, cytologic findings have not been reported. Objectives.—To review the cytologic features of histologically proven SPHTNs and to identify the potential diagnostic pitfalls in cytologic diagnosis. Materials and Methods.—Fine-needle aspiration cytology of 3 histologically proven SPHTNs was reviewed. Results.—Two girls and 1 boy (ages 11, 12, and 15 years) were affected. The cytologic diagnosis in all 3 cases was suspicious for papillary thyroid carcinoma (PTC). The spectrum of cytologic findings included broad flat sheets and 3-dimensional clusters with fire flares. There was mild to moderate nuclear pleomorphism and nuclear atypia. Short nonbranching papillae with transgressing vessels shown to represent hyperplastic papillae on histologic sections were identified in all cases. The background contained giant cells, histiocytes, and watery and inspissated colloid. Although nuclear grooves were identified in occasional cells, intranuclear inclusions were absent. A cell block section (1 case) and histologic sections of SPHTNs (2 cases) were immunohistochemically negative for cytokeratin 19. Conclusions.—Fine-needle aspiration of SPHTNs may be difficult to interpret accurately and can result in false-positive diagnosis of PTC. Although it shares several cytologic features with PTC, the presence of fire flares and short nonbranching papillae, as well as lack of intranuclear inclusions and watery and inspissated colloid in SPHTN appear to be useful features that are helpful in distinguishing SPHTN from PTC. Negative immunohistochemical staining for cytokeratin 19 is useful in excluding a diagnosis of PTC.

scholarly journals Case of Lingual Cysticercosis and Review of Literature

2012 ◽  
Vol 4 (01) ◽  
pp. 056-058 ◽  
Author(s):  
Arvind Kinger ◽  
Mallika Kawatra ◽  
Tej Singh Chaudhary
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Excision Biopsy ◽  
Review Of Literature ◽  
Aspiration Cytology ◽  
Lateral Border ◽  
Fine Needle ◽  
Tongue Muscles ◽  
Needle Aspiration Cytology

ABSTRACTA 30-year-old female presented with a painless solitary swelling at right lateral border of tongue of 2-month duration. Fine-needle aspiration cytology was nonconclusive. Excision biopsy was done. Histopathology revealed cysticercosis cellulosae and parasite visualized in the slide with tongue muscles. Lingual cysticercosis is rare and therefore its literature is reviewed and discussed.

scholarly journals A case report of 29 year old male patient with breast carcinoma: diagnosed on fine needle aspiration cytology

2019 ◽  
Vol 8 (1) ◽  
pp. 375
Author(s):  
Komal Patel ◽  
Pallavi Chaudhri ◽  
Siddhi M. Patel
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Male Breast ◽  
Breast Cancers ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology

Breast cancer has been considered a female dominated disease. Carcinoma of male breast is a rare disease representing 1% of all breast cancers and less than 1 % of all cancers in men. The mean age at presentation is mainly in sixties. We here present a case of male breast cancer presented at very young age of 29 years, diagnosed on fine needle aspiration which was confirmed later on histopathological examination.

Fine-Needle Aspiration Cytology in the Diagnosis of Breast Paraffinoma

2021 ◽  
pp. 1-5
Author(s):  
Kenneth Y.Y. Kok ◽  
Pemasiri Upali Telisinghe ◽  
Sonal Tripathi
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Diagnostic Procedures ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Multinucleated Giant Cells ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<b><i>Introduction:</i></b> Paraffin injections for breast augmentation once a popular form of mammoplasty are now considered obsolete. It had been abandoned by clinicians because of its associated serious complications. The practice is however still available and is being practiced by nonmedically qualified people. Paraffin injection results in the formation of multiple foreign-body granulomas known as breast paraffinoma. The clinical features of breast paraffinoma can mimic and be mistaken for breast carcinoma or inflammatory breast carcinoma. The use of fine-needle aspiration cytology (FNAC) in the evaluation of patients with breast paraffinoma has not been fully evaluated. <b><i>Methods:</i></b> Retrospective review was performed on 30 patients who presented with breast paraffinoma between June 1, 2010, and June 30, 2020, who also had FNAC as part of their breast lump evaluation. <b><i>Results:</i></b> FNAC of 73.3% patients showed multinucleated giant cells and macrophages or histiocytes containing engulfed clear, empty intracytoplasmic vacuoles of varying sizes. In 13.3% of the patients, macrophages or histiocytes with engulfed clear intracytoplasmic vacuoles of varying sizes were seen. In 6.7% of patients, multinucleated giant cells containing engulfed vacuoles of varying sizes were seen, and in 6.7% of patients, hypocellular smears with large amount of clear spaces were seen. Oily droplets were seen in the background of all the smears, and there were no malignant cells seen. These features were compatible with breast paraffinoma. <b><i>Conclusion:</i></b> Most patients with breast paraffinoma can be managed conservatively and they do not require further treatment; FNAC with its characteristic features can provide the reliable diagnosis of breast paraffinoma and therefore sparing these patients from more invasive diagnostic procedures.

scholarly journals Efficacy of Sonoelastography Images in Solitary Cold Thyroid Nodule and Compared with Fine Needle Aspiration Cytology Findings (FNAC)

2018 ◽  
Vol 19 (2) ◽  
pp. 103 ◽  
Author(s):  
Jasmin Ferdous ◽  
Mahbub Ur Rahman ◽  
Hosne Ara Rahman ◽  
Jamiul Hossain ◽  
Samira Sharmin ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Ultrasound Elastography ◽  
Aspiration Cytology ◽  
Predictive Values ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology

<p><strong>Objective: </strong>To evaluate the validity of sonoelastography of cold thyroid nodule in diagnosis of malignant nodule with fine needle aspiration cytology analysis as the reference standard.</p><p><strong>Patients and Methods: </strong>This cross sectional study was conducted in the Institute of Nuclear Medicine &amp; Allied Sciences (INMAS), Sir Salimullah Medical College (SMC) &amp; Mitford Hospital campus, Dhaka, from July 2015 to June 2016 in 85 patients with solitary solid cold nodule.  Eighty five nodules in these patients were examined by conventional ultrasound, ultrasound elastography and radionuclidescan. The final diagnosis was obtained from cytological findings. Tissue stiffness on ultrasound elastography was scored from 1 (low stiffness over the entire nodule) to 4 (high stiffness over the entire nodule).</p><p><strong>Results: </strong>The mean age was found 33.8±10.1 years with range from 12 to 58 years and male to female ratio was 1:5.1. The mean size of nodules was found 2.0±0.6 cm. Most (40.0%) of the patients were found in elastography score 2, 22(25.9%) score 1, 17(20.0%) score 4 and 12(14.1%) score 3. The validity of elastography scores had sensitivity 77.8%, specificity 86.2%, accuracy 83.5%, positive predictive values 72.4% and negative predictive values 89.3% for prediction of thyroid nodule.</p><p><strong>Conclusion: </strong>Considering the validity parameter the elastography may be effective diagnostic modality for evaluation of thyroid nodule.</p><p>Bangladesh J. Nuclear Med. 19(2): 103-106, July 2016</p>

Sign in / Sign up

Export Citation Format

Share Document