scholarly journals Changes in the Intra-Amniotic Pressure following Transabdominal Amnioinfusion during Pregnancy

2021 ◽  
pp. 86-91
Author(s):  
Daisuke Katsura ◽  
Yuichiro Takahashi ◽  
Shigenori Iwagaki ◽  
Rika Chiaki ◽  
Kazuhiko Asai ◽  
...  

<b><i>Objective:</i></b> The aim of the article was to investigate the changes in intra-amniotic pressure following transabdominal amnioinfusion during pregnancy. <b><i>Design:</i></b> This retrospective study included 19 pregnant women who underwent transabdominal amnioinfusion during pregnancy to relieve umbilical cord compression and improve the intrauterine environment or to increase the accuracy of ultrasonography. <b><i>Materials and Methods:</i></b> We measured and analyzed the changes in intra-amniotic pressure, single deepest pocket, and the amniotic fluid index before and after amnioinfusion. We also determined the incidence of maternal or fetal adverse events, such as preterm premature rupture of membranes, preterm delivery, fetal death within 48 h, placental abruption, infection, hemorrhage, and peripheral organ injury. <b><i>Results:</i></b> A total of 41 amnioinfusion procedures were performed for 19 patients. The median gestational age during the procedure was 24.3 weeks. The median volume of the injected amniotic fluid was 250 mL. The median single deepest pocket and amniotic fluid index after amnioinfusion were significantly higher than those before amnioinfusion (4.0 cm vs. 2.65 cm; <i>p</i> &#x3c; 0.001 and 13.4 cm vs. 6.0 cm; <i>p</i> &#x3c; 0.001). However, the median (range) intra-amniotic pressure after amnioinfusion was not significantly different compared to that before amnioinfusion (11 mm Hg vs. 11 mm Hg; <i>p</i> = 0.134). Maternal or fetal adverse events were not observed following amnioinfusion. <b><i>Conclusion:</i></b> Intra-amniotic pressure remained unchanged following amnioinfusion. The complications associated with increased intra-amniotic pressure are not likely to develop if the amniotic fluid index and/or single deepest pocket remains within the normal range after amnioinfusion. Studies of groups with and without complications are warranted to clarify the relationship between the intra-amniotic pressure and incidence of complications.

2011 ◽  
pp. 20-24
Author(s):  
Thi My Dung Ha ◽  
Ngoc Thanh Cao ◽  
Thi Song Huong Tran

Objective: To characterize ultrasound images of placenta and amniotic fluid in cases of singleton pregnancies beyond term predictions, and also explore the relationship between placenta, amniotic fluid and labor transfer status, postpartum child status. Image properties of prenatal placenta and amniotic fluid are immediately examined with ultrasound in 267 cases of postterm pregnancy beyond prediction at Obstetric Department, Hue Central Hospital. Results: In postterm pregnancy, placenta thickness decreases gradually according to gestational age. Oligohydramnios is 30.3%. There is a correlation between amniotic fluid index and birth method with r = 0.41. Sensitivity is 89.15%. Specificity is 48.55%. There is also a correlation between amniotic fluid echogenicity and method of birth: r = 0.478. Sensitivity is 97.67%. Specificity is 42.75%. Amniotic fluid index and baby Clifford's syndrome are also relevant, with r=0.466. Sensitivity is 83.78%. Specificity is 78.26%. Conclusions: Ultrasound scanning of amniotic fluid properties should be noted in the case of postterm pregnancy.


2003 ◽  
Vol 56 (1-2) ◽  
pp. 33-37 ◽  
Author(s):  
Aleksandra Novakov-Mikic ◽  
Sinisa Stojic ◽  
Mirjana Bogavac ◽  
Aljosa Mandic

Introduction Amniotic fluid volume reduction can have serious consequences prior to 24 gestational weeks hypoplasia of fetal lungs and later in pregnancy cord compression and fetal hypoxia as well as contractions of extremities. Diagnosis of oligohydramnios is made either after a subjective estimation of amniotic fluid reduction or if the biggest amniotic fluid pocket is less than 1 cm. Amnioinfusion is a procedure during which a crystalloid solution, most often saline, is instilled into the amniotic cavity substituting amniotic fluid. To estimate the efficacy and safety of amnioinfusion using our results and literature review. Material and methods Up to 800 ml of sterile saline solution was instilled intraamniotically (10-15 ml/min) in cases where the amniotic fluid index was less than 10 and intraamniotic infection was excluded. After that, 1 g of Longaceph was given intraamniotically. Infusion was stopped immediately when 800 ml was instilled, if a subjective estimation showed that there was enough fluid or if contractions occurred. Results During a six-month period there were five amnioinfusions - four therapeutical and one diagnostic; in four cases the procedure was successful and in one preterm rupture of membranes occurred 20 hours after the procedure. The procedure was most often done in the first half of the third trimester and continuation of pregnancy in successful cases was between 4 and 5 weeks, with average fetal weight gain of about 1200 gr No complications occurred in cases where pregnancy continued. Conclusion In our preliminary study amnioinfusion led to prolongation of pregnancy in majority of cases providing better maturation of fetal lungs and higher birth weight, without any complications. Further studies are necessary to reach definite conclusions about the efficacy and safety of amnioinfusion.


Author(s):  
Prashant Patil ◽  
Archana Kumari ◽  
H. P. Anand

Background: Preterm premature rupture of membrane (PPROM) is among the most important cause of the perinatal morbidity and mortality. We sought to determine whether cervical length and amniotic fluid index individually or in combination can predict the pregnancy outcome in cases of PPROM.Methods: The prospective observational study was done on 170 women complicated by PPROM with gestational age between 24-36+6 weeks. They were categorized into three groups Group I.24-28 weeks, Group II.28+1 to 32 weeks and Group III. 32+1 to 36+6 weeks. Cervical length and amniotic fluid index were measured using trans abdominal ultrasound within 24 hr of admission. Maternal outcomes were recorded in terms of latency period, chorioamnionitis, and abruption , and neonatal outcomes were recorded in terms of birth weight, first minute APGAR score <7, NICU admission and early neonatal death. Qualitative variables were correlated using Chi-Square test /Fisher’s exact test. Univariate logistic regression was used to assess cervical length and AFI as a predictor of complication. A p value of <0.05 was considered statistically significant.Results: Out of 170, majority (95) belonged to 28+1 to 32 weeks group. Latency was inversely related to period of gestation (p<0.0001). A long cervical length correlated with increased latency, increased risk of chorioamnionitis and increased neonatal complications in all three groups. Also, women with PPROM having AFI >5 cm had a greater mean latency period (8.32±1.25 days) which increased their risk of developing chorioamnionitis as compared to women with PPROM having AFI ≤5 cm, who had a shorter mean latency period (7.63±1.07 days) and a lower risk of developing chorioamnionitis (p value <0.0001).Conclusions: Latency is inversely related to period of gestation. A long cervical length and increased amount of AFI correlates with increased latency, increased risk of chorioamnionitis and increased neonatal complications.


1994 ◽  
Vol 11 (04) ◽  
pp. 249-252 ◽  
Author(s):  
William MacMillan ◽  
Stephanie Mann ◽  
Susan Shmoys ◽  
Daniel Saltzman

1991 ◽  
Vol 165 (4) ◽  
pp. 1088-1094 ◽  
Author(s):  
James A. Harding ◽  
David M. Jackson ◽  
David F. Lewis ◽  
Carol A. Major ◽  
Michael P. Nageotte ◽  
...  

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