scholarly journals Intravitreal injection is associated with increased posterior capsule rupture risk during cataract surgery: A meta-analysis

2021 ◽  
Author(s):  
Zhe Zhong ◽  
Zhenghua He ◽  
Xi Yu ◽  
Ying Zhang
Keyword(s):  
Cataract Surgery ◽  
Intravitreal Injection ◽  
Meta Analysis ◽  
Posterior Capsule ◽  
Current Evidence ◽  
Significant Heterogeneity ◽  
Odds Ratios ◽  
Increased Risk ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

Abstract Background: Although observational studies have suggested that prior intravitreal therapy may predict posterior capsule rupture (PCR) during cataract surgery, this finding is still controversial. Objective: To summarize current evidence on the association between prior intravitreal injection (IVI) and PCR during cataract surgery. Methods: A systematic literature search was performed up to October 27th, 2021. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using random-effects models. The potential association between IVI and PCR in future cataract surgeries was assessed using the following two models: “pooling the odds ratios of PCR in eyes with and without previous IVI(s)” and “pooling the odds ratios for PCR relative to each increase in the number of prior injections.” The quality of included studies was appraised using the Newcastle-Ottawa Scale. Results: 6 cohort studies were included in this meta-analysis, with a total of 1,051,097 eyes that underwent cataract surgery. Of these, 7,034 eyes were associated with previous IVI. The pooled odds of PCR in eyes with prior IVI was 2.01 (95% CI: 1.35–3.00) times higher than that of eyes without an IVI history. An increase in the number of previous IVI conferred increased odds of PCR of 1.03 (95% CI: 1.01–1.06). After excluding studies that failed to account for confounders, the significantly increased risk was not altered, and the significant heterogeneity was minimized in both models. Conclusion: This meta-analysis provides evidence that previous IVI significantly increases the risk of PCR during future cataract surgery. The risk of PCR should be discussed preoperatively with patients. Further studies are required to validate our findings and explore the underlying mechanisms.

Previous Intravitreal Therapy Is Associated with Increased Risk of Posterior Capsule Rupture during Cataract Surgery

Ophthalmology ◽  
2016 ◽  
Vol 123 (6) ◽  
pp. 1252-1256 ◽  
Author(s):  
Aaron Y. Lee ◽  
Alexander C. Day ◽  
Catherine Egan ◽  
Clare Bailey ◽  
Robert L. Johnston ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Posterior Capsule ◽  
Intravitreal Therapy ◽  
Increased Risk ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

Posterior Capsule Rupture during Cataract Surgery in Eyes Receiving Intravitreal anti-VEGF Injections

2020 ◽  
Vol 46 (2) ◽  
pp. 179-184
Author(s):  
D. Claire Miller ◽  
Karen L. Christopher ◽  
Jennifer L. Patnaik ◽  
Anne M. Lynch ◽  
Leonard K. Seibold ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Posterior Capsule ◽  
Anti Vegf ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

scholarly journals Intraoperative Complications of Cataract Surgery Using Intracameral Illumination in the Elderly over 75 Years

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Yu Jeong Kim ◽  
Su Jin Park ◽  
Jong Yeon Lee ◽  
Dae Yeong Lee ◽  
Dong Heun Nam
Keyword(s):  
Cataract Surgery ◽  
Intraoperative Complications ◽  
Case Series ◽  
The Elderly ◽  
Posterior Capsule ◽  
Anterior Capsule ◽  
Intraoperative Complication ◽  
Surgery Group ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

Purpose. To evaluate intraoperative complications and utilization of adjunctive devices between microscope and intracameral illuminations during cataract surgery in the elderly over 75 years. Design. A retrospective, consecutive, interventional case series Participants. Two hundred eighty-six eyes of 184 patients older than 75 years who underwent cataract surgery using microscope and intracameral illuminations. Methods. A chart review was performed on an advanced cataract surgery group of 141 consecutive cases in which the intracameral illumination was used and on a standard cataract surgery group of 145 consecutive cases in which the intracameral illumination was not used. Main Outcome Measures. Intraoperative complications (posterior capsule rupture, radial tear of the anterior capsule, dropped nucleus, or sulcus-implanted/sclera-fixated IOL) and utilization of adjunctive devices (pupil expansion device or anterior capsule staining). Results. The frequency of use of the pupil expansion device was lower in the advanced cataract surgery group than that in the standard cataract surgery group (0.7% vs 6.9%; p=0.007). Furthermore, the rates of a posterior capsule rupture and at least one intraoperative complication were lower in the advanced cataract surgery group than those in the standard cataract surgery group (0.7% vs 4.8%; p=0.067) (0.7% vs 7.6%; p=0.004). Conclusions. In the current cohort of patients over 75 years, the rate of intraoperative complications was lower when using the intracameral illumination than that when using the conventional method. Cataract surgery using intracameral illumination would be good option for elderly people.

scholarly journals Risk stratification for posterior capsule rupture and vitreous loss during cataract surgery

Eye ◽  
2009 ◽  
Vol 24 (2) ◽  
pp. 389-390 ◽  
Author(s):  
S Goverdhan ◽  
L Anderson ◽  
A Lockwood ◽  
J Kirwan
Keyword(s):  
Risk Stratification ◽  
Cataract Surgery ◽  
Posterior Capsule ◽  
Vitreous Loss ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

Short-term outcomes in eyes with posterior capsule rupture during cataract surgery

2003 ◽  
Vol 29 (3) ◽  
pp. 537-541 ◽  
Author(s):  
Fiona M. Chan ◽  
Ranjana Mathur ◽  
Jack J.K. Ku ◽  
Ching Chen ◽  
Siew-Pang Chan ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Posterior Capsule ◽  
Short Term ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture

scholarly journals Application of 25 MHz B-Scan Ultrasonography to Determine the Integrity of the Posterior Capsule in Posterior Polar Cataract

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Yawen Guo ◽  
Chengzhe Lu ◽  
Bin Wu ◽  
Jianmin Gao ◽  
Jun Li ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
The Other ◽  
Posterior Capsule ◽  
Slit Lamp ◽  
Appropriate Treatment ◽  
The Status ◽  
Posterior Capsule Rupture ◽  
Slit Lamp Microscopy ◽  
Capsule Rupture ◽  
Posterior Polar Cataract

Purpose. To report the application of 25 MHz B-scan ultrasonography (MHzB) to determine the integrity of the posterior capsule (PC) in posterior polar cataract (PPC). Methods. Patients with whom PPC was clinically diagnosed using slit lamp microscopy who underwent 25 MHzB before phacoemulsification were retrospectively reviewed. The status of the PC was determined by 25 MHzB before phacoemulsification and confirmed during cataract surgery. Results. In total, 21 eyes in 14 clinically diagnosed PPC patients were enrolled in this study. Out of 25 MHzB images, 19 PCs were found to be intact, while 2 showed dehiscence before cataract surgery. During phacoemulsification, 17 PCs were observed to be intact, while 4 PCs showed posterior capsule rupture (PCR). These 4 PCR cases included the above 2 eyes, in which preexisting dehiscence was detected by 25 MHzB. The other 2 PCR cases showed high reflectivity between high echoes in posterior opacities and the PC, indicating synechia between the PPC and PC. Conclusion. This is the first report to show that 25 MHzB can be used to clearly visualize the status of the PC in PPC. These results, in turn, could be used to select the appropriate treatment and to thereby avoid further complications during PPC surgery.

An anomalous foveal OCT-sign after posterior capsule rupture in cataract surgery: Complicated cataract surgery maculopathy

2020 ◽  
pp. 112067212093766
Author(s):  
Pietro Maria Talli ◽  
Emilio Pedrotti ◽  
Riccardo Sacconi ◽  
Cristina Monterosso ◽  
Luigi Caretti
Keyword(s):  
Cataract Surgery ◽  
Visual Impairment ◽  
Outer Segment ◽  
Posterior Capsule ◽  
Complicated Cataract ◽  
Frequent Event ◽  
Vitreous Loss ◽  
Posterior Capsule Rupture ◽  
Capsule Rupture ◽  
Sd Oct

Purpose: To report a series of novel optical coherence tomography (SD-OCT) foveal abnormalities, that we called “T-sign,” that were noticed after a complicated cataract surgery with posterior capsule rupture and vitreous loss. Methods: Retrospective case series of persistent foveal changes that incurred after anteroposterior vitreo-foveal traction secondary to phacoemulsification in presence of posterior capsule rupture. Results: The study included three eyes of three patients that incurred in complicated cataract surgery and intraoperative vitreo-foveal traction. During 8-month follow-up period peculiar abnormalities in fundus examination and in OCT scans were reported in all cases. Conclusion: Phacoemulsification in presence of posterior capsule rupture could induce a vitreo-foveal strain that could be transmitted to the cone outer segment tips (COST line) and inner–outer segment (IS/OS) junction. This focal stress is liable for “T-sign,” a persistent SD-OCT abnormality that induce a visual impairment and a slight metamorphopsia in the fixation point. Summary statement All over the world, more than 9.5 million cataract surgeries are completed each year.1 During surgery, many intraoperative complications could occur, and capsule rupture with vitreous loss is a frequent event. Phacoemulsification in presence of a wide posterior capsule rupture and vitreo-macular adhesion could induce a typical modification of the foveal structure and a permanent visual impairment.

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