scholarly journals Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog

2017 ◽  
Vol 54 (4) ◽  
pp. 420
Author(s):  
Thaís De Almeida Moreira ◽  
Leandro Willian Borges ◽  
Talita Lopes Serra ◽  
Diego Petrocino Caetano ◽  
Marcelo Carrijo da Costa ◽  
...  
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
S 100

O tumor maligno da bainha do nervo periférico é raro e pouco descrito em cães. Classicamente, o termo “neurofibroma/sarcoma” é empregado quando o tumor é composto por células de Schwann e células perineurais. Neste relato são descritos os achados clínicos, histopatológicos e imuno-histoquímicos de um caso de tumor maligno da bainha do nervo periférico, provavelmente neurofibrossarcoma, localizado no subcutâneo do membro pélvico de um cão da raça Rottweiler. Os achados histopatológicos associados às observações imuno-histoquímicas contribuíram para o diagnóstico, sendo observada positividade para proteína S-100, vimentina e CD57, permitindo a diferenciação da neoplasia em questão de outros tumores malignos com características morfológicas similares.

Malignant Peripheral Nerve Sheath Tumor of Frontal Sinus: A Case Report, Literature Review, and Immunohistochemical Study

2017 ◽  
Vol 3 (1) ◽  
pp. 1-3
Author(s):  
Mojtaba Babaei Zarch ◽  
Mansour Moghimi ◽  
Mohammad Hossein Dadgarnia ◽  
Seyed Mojtaba Ghelmani ◽  
Mohammad Baghi Yazdi ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Peripheral Nerve ◽  
Frontal Sinus ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant Triton Tumor without Von Recklinghausen’s Neurofibromatosis in a 16 year-old Indonesian Girl: A Case Report

2017 ◽  
Vol 43 (1) ◽  
pp. 3
Author(s):  
Neni Anggraini ◽  
Nurjati Chairani Siregar
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Early Detection ◽  
Peripheral Nerve ◽  
Correct Diagnosis ◽  
Nerve Sheath Tumor ◽  
Malignant Triton Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
S 100

Background: To diagnose malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation in malignant triton tumor which has a rare incidence. Case Illustration: We reported a case in a 16 year-old girl who presented with progressively painless proptosis of the left eye and decreased visual acuity. There was no evidence of Recklinghausen’s disease. She underwent surgery and radiotherapy. The histopatologic findings showed malignant peripheral nerve sheath tumor (MPNST). Four years later, she suffered recurrence proptosis and decreased visual acuity. Histomorphology supported by immunostaining with S-100 protein confirmed the diagnosis of malignant triton tumor. She underwent chemotherapy and enucleation. Conclusion: This case highlights the prudent use of immunohistochemistry that is essential in making an early detection and a correct diagnosis.

Malignant Peripheral Nerve Sheath Tumor of Frontal Sinus: A Case Report, Literature Review, and Immunohistochemical Study

2017 ◽  
Vol 3 (2) ◽  
pp. 1-3
Author(s):  
Mojtaba Babaei Zarch ◽  
Mansour Moghimi ◽  
Mohammad Hossein Dadgarnia ◽  
Seyed Mojtaba Ghelmani ◽  
Mohammad Baghi Yazdi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Peripheral Nerve ◽  
Frontal Sinus ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant peripheral nerve sheath tumor arising in benign ancient schwannoma: A case report with an immunohistochemical study

2000 ◽  
Vol 50 (2) ◽  
pp. 156-161 ◽  
Author(s):  
Yoshiki Mikami ◽  
Toshimi Hidaka ◽  
Takeshi Akisada ◽  
Takuji Takemoto ◽  
Isao Irei ◽  
...  
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

scholarly journals RARE-20. MALIGNANT PERIPHERAL NERVE SHEATH TUMOR OF A CRANIAL NERVE IN AN INFANT WITH NEUROCUTANEOUS MELANOSIS

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii446-iii446
Author(s):  
Lacey Carter ◽  
Naina Gross ◽  
Rene McNall-Knapp ◽  
,and Jo Elle Peterson
Keyword(s):  
Peripheral Nerve ◽  
Cranial Nerve ◽  
Leptomeningeal Disease ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Neurocutaneous Melanosis ◽  
Spindle Cell Neoplasm ◽  
Lower Back ◽  
Nerve Sheath ◽  
S 100

Abstract At one month of age, a female presented with a giant congenital nevus along lower back and thighs and hydrocephalus. A ventriculoperitoneal shunt was placed. An MRI was done at six months, initially reported as normal. At eleven months of age, five months after original MRI, patient presented with dysconjugate gaze and lethargy. MRI showed new 3.8 x 3.7 x 3.4 cm right cerebellopontine angle mass extending into Meckel’s cave and foramen ovale along with leptomeningeal disease extending from the mass along the entire length of the spinal cord. Retrospective review of prior MRI revealed subtle leptomeningeal enhancement concerning for neurocutaneous melanosis (NCM). Given the leptomeningeal disease, family elected for open biopsy and debulking of lesion instead of aggressive resection. Histologically, the mass showed hypercellular spindle cell neoplasm with mitotic activity and necrosis mixed with remnants of normal cranial nerve. GFAP was negative, excluding a glioma. HMB-45, MITF, panmelanoma, and Melan-A were negative, excluding melanoma. A negative myogenin stain ruled out ectomesenchymoma. S-100 protein and SOX-10 positivity with variable loss of staining for trimethylation of histone H3 K27 were indicative of malignant peripheral nerve sheath tumor (MPNST). Given the course of the mass, trigeminal nerve MPNST was presumed. Given the poor prognosis of intracranial MPNST and NCM, family elected to forgo treatment and was discharged with hospice. She died 25 days after surgery. Cranial nerve MPNST is rare. MPNST in patients with NCM has not previously been reported to our knowledge.

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