Local Continuity of Myocardial Blood Flow Studied by Monochromatic Synchrotron Radiation–Excited X-ray Fluorescence Spectrometry

1995 ◽  
Vol 76 (6) ◽  
pp. 1088-1100 ◽  
Author(s):  
Hidezo Mori ◽  
Mitsuaki Chujo ◽  
Shuichi Haruyama ◽  
Hiroyasu Sakamoto ◽  
Yoshiro Shinozaki ◽  
...  
1992 ◽  
Vol 263 (6) ◽  
pp. H1946-H1957 ◽  
Author(s):  
H. Mori ◽  
S. Haruyama ◽  
Y. Shinozaki ◽  
H. Okino ◽  
A. Iida ◽  
...  

We developed new nonradioactive microspheres and used more sensitive X-ray fluorescence spectrometers than used previously to measure regional blood flow in the heart and other organs. We demonstrated the chemical stability of eight kinds of heavy element-loaded microspheres and validated their use for regional blood flow measurement by comparing duplicate flows measured with radioactive and/or nonradioactive microspheres in both acute and chronic dog experiments. The wavelength-dispersive spectrometer (Philips PW 1480) has a higher sensitivity than the previously described X-ray fluorescent system and reduced the number of microspheres required for accurate measurement. The fine energy resolution of this system makes it possible to increase the numbers of different kinds of microspheres to be quantitated, but at present only eight kinds are available. We also used a synchrotron radiation-excited energy dispersive spectrometer. The monochromatic synchrotron radiation allowed us to obtain much higher signal-to-background ratios of X-ray fluorescence spectra than with the wavelength-dispersive system (50 dB more for Zr-loaded microspheres) and will enable analysis of fluorescent activity in smaller regions (< 20 mg) than the radioactive method does.


2019 ◽  
Vol 114 (8) ◽  
pp. 081904 ◽  
Author(s):  
Howie Joress ◽  
Shane Q. Arlington ◽  
Timothy P. Weihs ◽  
Joel D. Brock ◽  
Arthur R. Woll

2015 ◽  
Vol 64 (12) ◽  
pp. 867-874 ◽  
Author(s):  
Kentaro ISHII ◽  
Tomohiro TAKEKAWA ◽  
Yoshihito OHMAE ◽  
Yoshinori NISHIWAKI ◽  
Keiji GAMOH

1994 ◽  
Vol 349 (1-3) ◽  
pp. 144-145 ◽  
Author(s):  
W. Schmitt ◽  
J. Rothe ◽  
J. Hormes ◽  
W. H. Gries

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