Mitochondrial DNA Damage Can Promote Atherosclerosis Independently of Reactive Oxygen Species Through Effects on Smooth Muscle Cells and Monocytes and Correlates With Higher-Risk Plaques in Humans

Emma Yu; Patrick A. Calvert; John R. Mercer; James Harrison; Lauren Baker; Nichola L. Figg; Sheetal Kumar; Julie C. Wang; Liam A. Hurst; Daniel R. Obaid; Angela Logan; Nick E.J. West; Murray C.H. Clarke; Antonio Vidal-Puig; Michael P. Murphy; Martin R. Bennett

doi:10.1161/circulationaha.113.002271

Mitochondrial DNA Damage Can Promote Atherosclerosis Independently of Reactive Oxygen Species Through Effects on Smooth Muscle Cells and Monocytes and Correlates With Higher-Risk Plaques in Humans

Circulation ◽

10.1161/circulationaha.113.002271 ◽

2013 ◽

Vol 128 (7) ◽

pp. 702-712 ◽

Cited By ~ 124

Author(s):

Emma Yu ◽

Patrick A. Calvert ◽

John R. Mercer ◽

James Harrison ◽

Lauren Baker ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Response to Letter Regarding Article, “Mitochondrial DNA Damage Can Promote Atherosclerosis Independently of Reactive Oxygen Species Through Effects on Smooth Muscle Cells and Monocytes and Correlates With Higher-Risk Plaques in Humans”

Circulation ◽

10.1161/circulationaha.113.008032 ◽

2014 ◽

Vol 129 (12) ◽

Author(s):

Emma Yu ◽

Patrick A. Calvert ◽

John R. Mercer ◽

James Harrison ◽

Lauren Baker ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Faculty Opinions recommendation of Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718112876.793484359 ◽

2013 ◽

Author(s):

David Taylor ◽

Ethan Anderson

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Faculty Opinions recommendation of Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718112876.793483882 ◽

2013 ◽

Author(s):

Michael Sack

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Letter by Stocker and Maghzal Regarding Article, “Mitochondrial DNA Damage Can Promote Atherosclerosis Independently of Reactive Oxygen Species Through Effects on Smooth Muscle Cells and Monocytes and Correlates With Higher-Risk Plaques in Humans”

Circulation ◽

10.1161/circulationaha.113.005917 ◽

2014 ◽

Vol 129 (12) ◽

Author(s):

Roland Stocker ◽

Ghassan J. Maghzal

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Regulation of the Hypoxia-inducible Transcription Factor HIF-1 by Reactive Oxygen Species in Smooth Muscle Cells

Advances in Experimental Medicine and Biology - Chemoreception ◽

10.1007/978-1-4419-9280-2_22 ◽

2003 ◽

pp. 171-178 ◽

Cited By ~ 3

Author(s):

Rachida Siham Bel Aiba ◽

Agnes Görlach

Keyword(s):

Reactive Oxygen Species ◽

Transcription Factor ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species

Download Full-text

The role of mitochondrial DNA damage in the citotoxicity of reactive oxygen species

Journal of Bioenergetics and Biomembranes ◽

10.1007/s10863-011-9329-8 ◽

2011 ◽

Vol 43 (1) ◽

pp. 25-29 ◽

Cited By ~ 29

Author(s):

R. A. P. Costa ◽

C. D. Romagna ◽

J. L. Pereira ◽

N. C. Souza-Pinto

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Reactive Oxygen ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Inhibition of rac1 Reduces PDGF-induced Reactive Oxygen Species and Proliferation in Vascular Smooth Muscle Cells

Journal of Korean Medical Science ◽

10.3346/jkms.2001.16.6.712 ◽

2001 ◽

Vol 16 (6) ◽

pp. 712 ◽

Cited By ~ 20

Author(s):

Gu Kong ◽

Sahng Lee ◽

Kyung Soo Kim

Keyword(s):

Reactive Oxygen Species ◽

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species

Download Full-text

Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species and correlates with higher risk plaques in humans

Atherosclerosis ◽

10.1016/j.atherosclerosis.2013.11.005 ◽

2014 ◽

Vol 232 (2) ◽

pp. e3

Author(s):

E. Yu ◽

P.A. Calvert ◽

J.R. Mercer ◽

J. Harrison ◽

L. Baker ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Mitochondrial Dna ◽

Reactive Oxygen ◽

Oxygen Species ◽

Mitochondrial Dna Damage

Download Full-text

Reactive oxygen species-mediated regulation of thioredoxin translocation in vascular smooth muscle cells

Vascular Pharmacology ◽

10.1016/j.vph.2006.08.039 ◽

2006 ◽

Vol 45 (3) ◽

pp. 188 ◽

Cited By ~ 1

Author(s):

Cameron World ◽

Bradford Berk

Keyword(s):

Reactive Oxygen Species ◽

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species

Download Full-text

Reactive oxygen species mediate Endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 signaling, as well as protein synthesis, in vascular smooth muscle cells

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2004.04.018 ◽

2004 ◽

Vol 37 (2) ◽

pp. 208-215 ◽

Cited By ~ 61

Author(s):

Grace Bou Daou ◽

Ashok K Srivastava

Keyword(s):

Reactive Oxygen Species ◽

Protein Synthesis ◽

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Reactive Oxygen ◽

Muscle Cells ◽

Oxygen Species ◽

Endothelin 1

Download Full-text