scholarly journals Systolic Blood Pressure Variation and Mean Heart Rate Is Associated With Cognitive Dysfunction in Patients With High Cardiovascular Risk

Hypertension ◽  
2015 ◽  
Vol 65 (3) ◽  
pp. 651-661 ◽  
Author(s):  
Michael Böhm ◽  
Helmut Schumacher ◽  
Darryl Leong ◽  
Giuseppe Mancia ◽  
Thomas Unger ◽  
...  
1991 ◽  
Vol 80 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Henry Krum ◽  
William J. Louis ◽  
Douglas J. Brown ◽  
Graham P. Jackman ◽  
Laurence G. Howes

1. Measurement of blood pressure and heart rate over a 24 h period was peformed in 10 quadriplegic spinal cord injury patients and 10 immobilized, neurologically intact orthopaedic subjects by using the Spacelabs 90207 automated ambulatory monitoring system. 2. Systolic and diastolic blood pressure fell significantly at night in orthopaedic subjects but not in quadriplegic patients, and night-time blood pressures were similar in both groups. 3. Cumulative summation of differences from a reference value (cusum analysis) confirmed a markedly diminished diurnal blood pressure variation in the quadriplegic patients. 4. These findings could not be accounted for on the basis of blood pressure variations during chronic postural change. 5. Heart rate fell significantly at night in both groups. 6. The findings suggest that the increase in blood pressure during waking hours in neurologically intact subjects is a consequence of a diurnal variation in sympathetic activity (absent in quadriplegic patients with sympathetic decentralization) which is independent of changes in physical activity.


2017 ◽  
Vol 142 (19) ◽  
pp. 1420-1429 ◽  
Author(s):  
Rainer Düsing

AbstractThe optimal target blood pressure (BP) in the treatment of hypertensive patients remains controversial. Recently, the systolic blood pressure trial (SPRINT) has proposed that a target systolic blood pressure of < 120 mmHg provides prognostic benefit in elderly hypertensive patients at high cardiovascular risk. The results of SPRINT contrast with several other intervention trials which have investigated the effect of intense BP lowering (Secondary Prevention of Small Subcortical Strokes [SPS3], Action to Control Cardiovascular Risk in Diabetes [ACCORD], Heart Outcomes Prevention Evaluation [HOPE]-3). The differences in outcomes in SPRINT vs. other intervention trials are, to a large extend, due to an "unobserved" BP measurement procedure utilized in the SPRINT trial. Thus, a BP goal of < 120 mmHg, at least by conventional BP measurement, remains unproven. Independent of SPRINT the controversial evidence with respect to BP targets calls for further studies and, possibly, for more individualized treatment goals.


1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA ◽  
Author(s):  
M. Vrillon ◽  
F. Le Bret ◽  
J. Vrints ◽  
E. Barre ◽  
P. Coriat ◽  
...  

2018 ◽  
Vol 41 (7) ◽  
pp. 475-482 ◽  
Author(s):  
Pietro Amedeo Modesti ◽  
Stefano Rapi ◽  
Angela Rogolino ◽  
Benedetta Tosi ◽  
Giorgio Galanti

2007 ◽  
Vol 135 (1-2) ◽  
pp. 73
Author(s):  
Hiroshi Kawamura ◽  
Hiromi Mitsubayasi ◽  
Yoichi Izumi ◽  
Yukio Ozawa ◽  
Yuji Kasamaki ◽  
...  

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