scholarly journals National Institutes of Health–Funded Cardiac Arrest Research: A 10‐Year Trend Analysis

2017 ◽  
Vol 6 (7) ◽  
Author(s):  
Ryan A. Coute ◽  
Ashish R. Panchal ◽  
Timothy J. Mader ◽  
Robert W. Neumar
Keyword(s):  
Cardiac Arrest ◽  
Trend Analysis ◽  
National Institutes Of Health

scholarly journals 10-year trend analysis of in-hospital cardiac arrest: 2008–2017 United State hospitalizations

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
L Wu ◽  
C Huang Lucus ◽  
Y.F Yang ◽  
B.Q Liu ◽  
Y Guo
Keyword(s):  
United States ◽  
Cardiac Arrest ◽  
Trend Analysis ◽  
Inflation Rate ◽  
The United States ◽  
Baseline Characteristic ◽  
Comorbidity Burden ◽  
The Cost ◽  
Care Costs ◽  
Hospital Cardiac Arrest

Abstract Introduction In-hospital cardiac arrest (IHCA) survival trends have not been well reported in recent years. Whether the implementation of the new 2015 AHA guideline affects the survival of IHCA is largely unknown. Our study aims to provide an updated analysis of the trends of IHCA among the hospitals in the United States Method Using United States National Inpatient Sample Database 2008–2017, the cohort was generated with patients age above 18 who received Cardiopulmonary resuscitation during Hospitalization. Hospitalization with a principle diagnosis of cardiac arrest or ventricular fibrillation/ventricular tachycardia were excluded as outside hospital cardiac arrest. Demographic features, baseline characteristic as well as hospital outcomes were described. Trend analysis was performed using a multivariate model adjusted for age, sex, and comorbidities score. Results From 2008 to 2017, the cases of In-hospital cardiac arrest (IHCA) has steadily increased from 96,771 to 106,320. This trend was accompanied by a decline in age from (67.48±0.30 to 65.78±0.13, Ptrend <0.001) but increase in comorbidity score (from 2.44±0.27 to 3.47±0.21, Ptrend <0.001). It is noted that the mortality rate has been steadily declining since 2008 (from 74.01% to 68.68%, Ptrend <0.001)), although no significant changes before or after 2015 were noted (from 68.90 to 68.68, P>0.05). Length of stay has decreased from an average of 9.06± days to 8.76±0.13 days at the cost of increased health care costs (from 30.78 to 37.40 thousand dollar P<0.001 adjusted for inflation rate). Conclusion The survival rate of In-hospital cardiac arrest has increased from 2008 to 2017 despite increased comorbidity burden. The length of stays has decreased at the cost of an increase in health costs. Funding Acknowledgement Type of funding source: None

Abstract 310: National Institutes of Health Research Investment for the Leading Causes of Disability-Adjusted Life Years in the United States

Circulation ◽  
2019 ◽  
Vol 140 (Suppl_2) ◽  
Author(s):  
Ryan A Coute ◽  
Brian Nathanson ◽  
Michael C Kurz ◽  
Nathan L Haas ◽  
Bryan McNally ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Research Funding ◽  
The United States ◽  
National Institutes Of Health ◽  
Disability Adjusted Life Years ◽  
Inclusion Criteria ◽  
Research Investment ◽  
Disability Adjusted Life ◽  
Life Years ◽  
The U.S

Background: Cardiac arrest (CA) is a leading cause of disability-adjusted life years (DALY) in the United States (U.S.). The National Institutes of Health (NIH) does not report annual research funding for CA. Our objective was to calculate and compare the NIH research investment for CA to other leading causes of DALY in the U.S. Methods: A search within NIH RePORTER for the year 2016 was performed using the following terms: cardiac arrest, cardiopulmonary resuscitation, heart arrest, circulatory arrest, pulseless electrical activity, ventricular fibrillation, or resuscitation. Grants were individually reviewed and categorized as CA research (yes/no) using predefined criteria and the sum of funding for grants meeting inclusion criteria were tabulated. DALY were calculated as the sum of years of life lost (YLL) and years lived with disability (YLD) using all adult non-traumatic EMS-treated out-of-hospital CA (OHCA) from the CARES database for 2016. Total DALY for the study population were extrapolated to a national level. The leading causes of DALY were obtained from the Global Burden of Disease study. Funding data were extracted from the 2016 NIH Categorical Spending Report. Research funding were compared using U.S. dollars invested per DALY as the outcome measure. Results: The search yielded 285 NIH-funded grants, of which 65 (22.8%) were classified as CA research. Total NIH funding for CA research in 2016 was $28.5M. A total of 59,752 cases from CARES met study inclusion criteria for the DALY analysis. The total DALY following adult OHCA in the U.S. were 4,354,192 (YLL 4,350,825; YLD 3,365). Per annual DALY, the NIH invested $284 for diabetes, $89 for stroke, $53 for ischemic heart disease, and $7 for CA research in 2016 (FIGURE). Conclusion: The NIH investment into CA research is less than other leading causes of death and disability in the U.S. These results should help inform the debate regarding how to best utilize limited resources to improve public health.

The 1-MeV Electron Microscope Installation at the University of Colorado

1973 ◽  
Vol 31 ◽  
pp. 8-9 ◽  
Author(s):  
Mircea Fotino
Keyword(s):  
Electron Microscopy ◽  
Developmental Biology ◽  
Transmission Electron Microscopy ◽  
Electron Microscope ◽  
National Institutes Of Health ◽  
Experimental Program ◽  
University Of Colorado ◽  
Transmission Electron ◽  
The University ◽  
Research Resources

A new 1-MeV transmission electron microscope (Model JEM-1000) was installed at the Department of Molecular, Cellular and Developmental Biology of the University of Colorado in Boulder during the summer and fall of 1972 under the sponsorship of the Division of Research Resources of the National Institutes of Health. The installation was completed in October, 1972. It is installed primarily for the study of biological materials without many of the limitations hitherto unavoidable in standard transmission electron microscopy. Only the technical characteristics of the installation are briefly reviewed here. A more detailed discussion of the experimental program under way is being published elsewhere.

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