Abstract 94: Blood Pressure After Endovascular Stroke Therapy (BEST): Final Results of a Prospective Multicenter Cohort Validation Study

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Eva A Mistry ◽  
Heidi Sucharew ◽  
Akshitkumar M Mistry ◽  
Tapan Mehta ◽  
Niraj Arora ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Validation Study ◽  
Stroke Therapy ◽  
Multicenter Cohort ◽  
Endovascular Stroke Therapy

Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Anson Wang ◽  
David M Mampre ◽  
Kevin N Sheth ◽  
Can O Tan ◽  
Charles C Matouk ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Functional Outcome ◽  
Blood Pressure Reduction ◽  
Pressure Reduction ◽  
Stroke Therapy ◽  
Poor Functional Outcome ◽  
Endovascular Stroke Therapy

scholarly journals 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome

Neurosurgery ◽  
2018 ◽  
Vol 65 (CN_suppl_1) ◽  
pp. 82-82
Author(s):  
David Mampre ◽  
Anson Wang ◽  
Kevin Sheth ◽  
Can Ozan Tan ◽  
Ryan M Hebert ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Functional Outcome ◽  
Stroke Therapy ◽  
Poor Functional Outcome ◽  
Endovascular Stroke Therapy

scholarly journals Association of Personalized Blood Pressure Targets With Hemorrhagic Transformation and Functional Outcome After Endovascular Stroke Therapy

2019 ◽  
Vol 76 (10) ◽  
pp. 1256 ◽  
Author(s):  
Nils H. Petersen ◽  
Andrew Silverman ◽  
Anson Wang ◽  
Sumita Strander ◽  
Sreeja Kodali ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Functional Outcome ◽  
Hemorrhagic Transformation ◽  
Stroke Therapy ◽  
Blood Pressure Targets ◽  
Endovascular Stroke Therapy

Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke Therapy

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Sumita Strander ◽  
Anson Wang ◽  
Sreeja Kodali ◽  
Andrew Silverman ◽  
Tijil Agarwal ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ct Perfusion ◽  
Stroke Therapy ◽  
Increased Sensitivity ◽  
Endovascular Stroke Therapy

Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional Outcome

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Nils H Petersen ◽  
Anson Wang ◽  
Binbin Zhen-Li ◽  
Sumita Strander ◽  
Sreeja Kodali ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Functional Outcome ◽  
Stroke Therapy ◽  
Poor Functional Outcome ◽  
Endovascular Stroke Therapy

scholarly journals Noncontrast CT versus Perfusion‐Based Core Estimation in Large Vessel Occlusion: The Blood Pressure after Endovascular Stroke Therapy Study

2020 ◽  
Vol 30 (2) ◽  
pp. 219-226 ◽  
Author(s):  
James E. Siegler ◽  
Steven R. Messé ◽  
Heidi Sucharew ◽  
Scott E. Kasner ◽  
Tapan Mehta ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Large Vessel ◽  
Large Vessel Occlusion ◽  
Stroke Therapy ◽  
Vessel Occlusion ◽  
Noncontrast Ct ◽  
Endovascular Stroke Therapy

scholarly journals Rapid Assessment of Blood Pressure Variability and Outcome After Successful Thrombectomy

Stroke ◽  
2021 ◽  
Author(s):  
Pedro Castro ◽  
Francisca Ferreira ◽  
Cindy K. Nguyen ◽  
Seyedmehdi Payabvash ◽  
Can Ozan Tan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Spectral Analysis ◽  
High Frequency ◽  
Functional Outcomes ◽  
Clinical Decision Making ◽  
Assessment Tool ◽  
Rapid Assessment ◽  
Neurological Recovery ◽  
Stroke Therapy ◽  
Endovascular Stroke Therapy

Background and Purpose: High blood pressure (BP) variability after endovascular stroke therapy is associated with poor outcome. Conventional BP variability measures require long recordings, limiting their utility as a risk assessment tool to guide clinical decision-making. Here, we performed rapid assessment of BP variability by spectral analysis and evaluated its association with early clinical improvement and long-term functional outcomes. Methods: We conducted a prospective study of 146 patients with anterior circulation ischemic stroke who underwent successful endovascular stroke therapy. Spectral analysis of 5-minute recordings of beat-to-beat BP was used to quantify BP variability. Outcomes included initial clinical response and modified Rankin Scale at 90 days. Results: Increased BP variability at high frequencies was independently associated with poor functional outcome at 90 days (adjusted odds ratio [aOR], 1.85 [95% CI, 1.07–3.25], P =0.03; low-/high-frequency ratio aOR, 0.67 [95% CI, 0.46–0.92], P =0.02) and reduced likelihood of an early neurological recovery (aOR, 0.62 [95% CI, 0.44–0.91], P =0.01 and aOR, 1.37 [95% CI, 1.03–1.87], P =0.04, respectively). Conclusions: High-frequency BP oscillations after successful reperfusion may be harmful and associate with a decreased likelihood of neurological recovery and favorable functional outcomes. Rapid assessment of BP variability throughout the postreperfusion period is feasible and may allow for a more personalized BP management.

Abstract WP23: Comparison of Suction Thrombectomy, Stentriever, and Combined Approach: Thrombus Size, Fragmentation, and Outcome - A Single Center Analysis

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Wolfgang Leesch ◽  
Pankajavalli Ramakrishnan ◽  
Dean Kostov ◽  
O’Brien Gossage ◽  
Frank Sanderson
Keyword(s):  
Clinical Outcome ◽  
Combined Approach ◽  
Stroke Therapy ◽  
Distal Embolization ◽  
Radiographic Images ◽  
Single Pass ◽  
Size Number ◽  
Data Points ◽  
Combined Technique ◽  
Endovascular Stroke Therapy

Introduction: Few reports have compared the commonly used technical approaches of stentriever, suction thrombectomy, and combined technique, particularly with emphasis on thrombus volume, fragmentation, distal embolization, and clinical outcome. Methods: Medical records and radiographic images of patients undergoing endovascular stroke therapy at our institution between 2014 and 2015 were reviewed for the following data points: Patient age, sex, NIH stroke scale (NIHSS) at presentation, number of passes, presence of distal embolization on angiography, TICI score, and Modified Rankin Scale (MRS) at discharge. When available, photographic images of the retrieved thrombus were analyzed for number of fragments and size of the largest fragment. Parameters were compared for the three thrombectomy techniques of suction (ADAPT technique), stentriever, and the combined approach. Results: Of 63 patients receiving endovascular stroke therapy, 47 (75%) underwent mechanical thrombectomy: Stentriever 17 (36%), Suction 18 (38%), and combined 12 (26%). Average age and presenting NIH stroke scales were similar in the groups. A single pass thrombectomy was more common in the suction group (72%) than in the stentriever (29%) and combined groups (8%). There were more thrombus fragments in the stentriever (2.3) and combined groups (3.4) than in the suction group (1.4), correlating to more frequent distal embolization (suction 22%, stentriever 70%, combined 50%). The retrieved thrombus was largest in the suction group (12.9 mm; stentriever 6.6 mm; combined 10.4 mm). Overall outcome at discharge was better in the suction group (61% MRS 0-2) than in the stentriever (35%) and combined groups (17%). Conclusions: In our patient sample suction thrombectomy outperformed the stentriever and combined techniques in the categories of achieved reperfusion grade, single pass, retrieved thrombus size, number of fragments, distal embolization and clinical outcome. While stent retriever and suction thrombetomy were used as primary approaches, the combined technique was commonly utilized as a rescue attempt once the primary approach had failed, constituting a potential limitation of the analysis in this category.

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