scholarly journals Tissue Protrusion With Attenuation Is Associated With Ischemic Brain Lesions After Carotid Artery Stenting

Stroke ◽  
2020 ◽  
Vol 51 (1) ◽  
pp. 327-330 ◽  
Author(s):  
Naoko Funatsu ◽  
Yukiko Enomoto ◽  
Yusuke Egashira ◽  
Keita Yamauchi ◽  
Noriyuki Nakayama ◽  
...  

2021 ◽  
Vol 11 (6) ◽  
pp. 2669-2676
Author(s):  
Peng Lv ◽  
Aihua Ji ◽  
Ranying Zhang ◽  
Daqiao Guo ◽  
Xiao Tang ◽  
...  


2015 ◽  
Vol 65 (6) ◽  
pp. 521-529 ◽  
Author(s):  
Henrik Gensicke ◽  
H. Bart van der Worp ◽  
Paul J. Nederkoorn ◽  
Sumaira Macdonald ◽  
Peter A. Gaines ◽  
...  








Neurology ◽  
2018 ◽  
Vol 90 (15) ◽  
pp. e1283-e1290 ◽  
Author(s):  
Chuanjie Wu ◽  
Chuanhui Li ◽  
Wenbo Zhao ◽  
Nanchang Xie ◽  
Feng Yan ◽  
...  

ObjectivesTo investigate whether the plasma level of trimethylamine N-oxide (TMAO), a proatherosclerotic intestinal microbiota metabolite, can be a predictor of ischemic brain injury secondary to carotid artery stenting (CAS).MethodsIn this multicenter, prospective cohort study, we enrolled patients with severe carotid artery stenosis (>70%) who were prepared for CAS. Plasma TMAO level was measured within 3 days before CAS, and MRI was performed 1 to 3 days after CAS.ResultsThe mean age of the 268 eligible patients was 64.4 years. New lesions on diffusion-weighted imaging (DWI) were detected in 117 patients (43.7%). TMAO level was higher in patients with new (DWI) lesions than in patients without new lesions (median 5.2 vs 3.2 µmol/L; p < 0.001). Increased plasma TMAO levels were associated with an increased risk of having new lesions on DWI after CAS (adjusted odds ratio for the highest vs lowest quartile, 3.85; 95% confidence interval, 1.37–7.56, p < 0.001; adjusted odds ratio for the third vs lowest quartile, 1.86; 95% confidence interval, 1.09–4.66, p = 0.02). The area under the receiver operating characteristic curve of TMAO was 0.706 for new lesions on DWI, and the optimal cutoff value was 4.29 µmol/L. The sensitivity, specificity, positive predictive value, and negative predictive value of TMAO levels ≥4.29 µmol/L for predicting new lesions on DWI were 61.5%, 74.8%, 65.5%, and 65.5%, respectively.ConclusionsIncreased TMAO levels are associated with an increased risk of new ischemic brain lesions on post-CAS MRI scans.





Neurology ◽  
2003 ◽  
Vol 60 (9) ◽  
pp. 1435-1441 ◽  
Author(s):  
R. H.C. Bisschops ◽  
C. J.M. Klijn ◽  
L. J. Kappelle ◽  
A. C. van Huffelen ◽  
J. van der Grond


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