Characterization of neural stem cells on electrospun poly(ε-caprolactone) submicron scaffolds: evaluating their potential in neural tissue engineering

2008 ◽  
Vol 19 (5) ◽  
pp. 623-634 ◽  
Author(s):  
D. R. Nisbet ◽  
L. M. Y. Yu ◽  
T. Zahir ◽  
J. S. Forsythe ◽  
M. S. Shoichet
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Neural Tissue ◽  
Neural Tissue Engineering

scholarly journals Effects of Graphene-Based Materials on the Behavior of Neural Stem Cells

2020 ◽  
Vol 2020 ◽  
pp. 1-16 ◽  
Author(s):  
Yan Zhang ◽  
Shu Wang ◽  
Ping Yang
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Transverse Myelitis ◽  
Neural Tissue ◽  
Research Field ◽  
Benign Tumors ◽  
Neural Tissue Engineering ◽  
Coating Materials ◽  
Differentiation And Proliferation

Neural tissue engineering is a research field aimed at rebuilding neurological defects resulting from severe trauma, vascular impairment, syringomyelia, spinal stenosis, malignant and benign tumors, or transverse myelitis. Of particular interest, neural stem cells (NSCs) and the effective differentiation and proliferation thereof are attractive research areas that have yielded widespread utility for implants or neural scaffold materials. Graphene and its derivatives have more effective and efficient physical, chemical, and biological abilities than other nanomaterials, and may act as new coating materials to promote neuronal proliferation and differentiation. Therefore, here, we review the recent progress of studies that examine the effect of graphene-based materials on NSCs. We specifically review how graphene and its derivatives influence NSC adhesion, differentiation, and proliferation. We also discuss the risks of graphene-based materials, including their anti-inflammatory effects, in the realm of neural tissue engineering as well as current challenges facing the field today.

A novel bioactive peptide: assessing its activity over murine neural stem cells and its potential for neural tissue engineering

2013 ◽  
Vol 30 (5) ◽  
pp. 552-562 ◽  
Author(s):  
Andrea Caprini ◽  
Diego Silva ◽  
Ivan Zanoni ◽  
Carla Cunha ◽  
Carolina Volontè ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Neural Tissue ◽  
Bioactive Peptide ◽  
Neural Tissue Engineering

Enhanced Cellular Activity on Conducting Polymer

2021 ◽  
pp. 734-773
Author(s):  
Rajiv Borah ◽  
Ashok Kumar
Keyword(s):  
Tissue Engineering ◽  
Conducting Polymer ◽  
Neural Tissue ◽  
Neuronal Model ◽  
Neural Tissue Engineering ◽  
Electrically Conductive ◽  
Pc12 Cell Line ◽  
Nih 3T3

This chapter includes detailed review of the research undertaken with conducting polymer (CP) based composites with chitosan (Ch) for tissue engineering till date. The beneficial role of electrically conductive biomaterials has been discussed with the possible strategies to overcome the shortcomings of CP alone through blending with Ch due to its excellent biocompatibility, biodegradability, and bioactivity. Additionally, this embodiment deals with the optimization and characterization of electrically conductive, biocompatible and biodegradable Polyaniline: Chitosan (PAni:Ch) nanocomposites as cell culture substrates for MDA-MB-231 and NIH 3T3 fibroblast in order to examine the combined effect of nanofiber structure and surface modification on cell-biomaterial interactions. The nanocomposites were further checked as a conductive scaffold for electrical stimulation of a neuronal model PC12 cell line in order to explore the potential of the materials in neural tissue engineering.

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