Study of Focusing of Field Refracted by a Cylindrical Plano-Convex Lens Into a Uniaxial Crystal by Using Maslov's Method

New technologies have powered rapid advances in cellular imaging, genomics and phenotypic analysis in life sciences. However, most of these methods operate at sample population levels and provide statistical averages of aggregated data that fail to capture single-cell heterogeneity, complicating drug discovery and development. Here we demonstrate a new single-cell approach based on convex lens-induced confinement (CLiC) microscopy. We validated CLiC on yeast cells, demonstrating subcellular localization with an enhanced signal-to-noise and fluorescent signal detection sensitivity compared with traditional imaging. In the live-cell CLiC assay, cellular proliferation times were consistent with flask culture. Using methotrexate, we provide drug response data showing a fivefold cell size increase following drug exposure. Taken together, CLiC enables high-quality imaging of single-cell drug response and proliferation for extended observation periods.

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Fabrication of convex lens-shaped polymer particles by tuning the interfacial interaction

Materials Chemistry Frontiers ◽

10.1039/c6qm00072j ◽

2017 ◽

Vol 1 (3) ◽

pp. 507-511 ◽

Cited By ~ 15

Author(s):

Jiangping Xu ◽

Yi Yang ◽

Ke Wang ◽

Yuqing Wu ◽

Jintao Zhu

Keyword(s):

Block Copolymers ◽

Small Molecules ◽

Interfacial Interaction ◽

Polymer Particles ◽

Emulsion Droplets ◽

Convex Lens ◽

Cylindrical Domains

With the addition of small molecules to emulsion droplets containing block copolymers, anisotropic convex lens-like particles with hexagonally stacked cylindrical domains can be readily achieved by using a single surfactant to create a neutral interface for both blocks.

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Upconversion of Broadband Infrared Radiation into Visible Light for Different Pumping Parameters

Journal of Spectroscopy ◽

10.1155/2013/631510 ◽

2013 ◽

Vol 2013 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Man Nen Litvinova ◽

Victor Krishtop ◽

Evgeniy Tolstov ◽

Vladimir Troilin ◽

Larisa Alekseeva ◽

...

Keyword(s):

Lithium Niobate ◽

Visible Light ◽

Light Beam ◽

Infrared Radiation ◽

Spectral Width ◽

Uniaxial Crystal ◽

Phase Matching ◽

Pump Radiation ◽

Broadband Radiation ◽

Lithium Niobate Crystals

The influence of pump radiation parameters such as the polarization and the spectral width of infrared radiation on the conversion of broadband radiation in lithium niobate crystals was investigated. The spectra of converted radiation were calculated for two types of phase matching in the negative uniaxial crystal by taking into account the convergence of the light beam in the crystal. Experimental spectra were obtained and compared with the calculated spectra.

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Ray equation for a spatially variable uniaxial crystal and its use in the optical design of liquid-crystal lenses

Journal of the Optical Society of America A ◽

10.1364/josaa.24.002089 ◽

2007 ◽

Vol 24 (7) ◽

pp. 2089 ◽

Cited By ~ 12

Author(s):

Charles Jenkins ◽

Richard Bingham ◽

Kenneth Moore ◽

Gordon D. Love

Keyword(s):

Liquid Crystal ◽

Optical Design ◽

Uniaxial Crystal

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Preparation, Growth Mechanism, Upconversion, and Near-Infrared Photoluminescence Properties of Convex-Lens-like NaYF4 Microcrystals Doped with Various Rare Earth Ions Excited at 808 nm

Crystal Growth & Design ◽

10.1021/acs.cgd.7b01667 ◽

2018 ◽

Vol 18 (3) ◽

pp. 1758-1767 ◽

Cited By ~ 15

Author(s):

Yingjin Ma ◽

Zhengwen Yang ◽

Hailu Zhang ◽

Jianbei Qiu ◽

Zhiguo Song

Keyword(s):

Rare Earth ◽

Growth Mechanism ◽

Near Infrared ◽

Rare Earth Ions ◽

Photoluminescence Properties ◽

Convex Lens

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The Magnetic Anisotropy of Stretched Rubber as a Function of the Tension to Which It Is Subjected

Rubber Chemistry and Technology ◽

10.5254/1.3543206 ◽

1945 ◽

Vol 18 (1) ◽

pp. 8-9 ◽

Cited By ~ 1

Author(s):

Eugénie Cotton-Feytis

Keyword(s):

Magnetic Field ◽

Magnetic Anisotropy ◽

Uniaxial Crystal ◽

Horizontal Magnetic Field ◽

First Approximation ◽

The Difference ◽

The Times ◽

Angular Displacements ◽

The Magnetic Field ◽

Oscillation Method

Abstract From the standpoint of its magnetic anisotropy, stretched rubber is comparable in a first approximation to a uniaxial crystal, in which the direction of the axis is the same as the direction of elongation. It is possible to measure this anisotropy by means of the oscillation method used by Krishnan, Guha and Banerjee in studying crystals. The sample to be examined is suspended in a uniform horizontal magnetic field in such a manner that its axis is horizontal. It is then so arranged that the torsion of the suspension wire is zero when the rubber sample is in a position of equilibrium in the field. The times of oscillation T′ and T for very small angular displacements around this position, in the presence and then in the absence of the magnetic field, are then recorded. In this way the difference between the specific susceptibilities in the direction of the axis and in the horizontal direction perpendicular to the axis is calculated by application of the equation:

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