Non-Invasive Diagnosis of the Etiology of Acute Pulmonary Edema Using the Edema Fluid-to-Plasma Protein Ratio.

2009 ◽  
Author(s):  
LB Ware ◽  
RD Fremont ◽  
JA Bastarache ◽  
CS Calfee ◽  
MA Matthay
Keyword(s):  
Pulmonary Edema ◽  
Plasma Protein ◽  
Acute Pulmonary Edema ◽  
Protein Ratio ◽  
Non Invasive ◽  
Edema Fluid

scholarly journals Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Irina Gavrilovskaya ◽  
Elena Gorbunova ◽  
Frederick Koster ◽  
Erich Mackow
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Endothelial Cells ◽  
Pulmonary Edema ◽  
Vascular Permeability ◽  
Hantavirus Pulmonary Syndrome ◽  
Acute Pulmonary Edema ◽  
Vascular Endothelial ◽  
Edema Fluid ◽  
Endothelial Growth Factor

Hantavirus pulmonary syndrome is characterized by vascular permeability, hypoxia, and acute pulmonary edema. Vascular endothelial growth factor (VEGF) is induced by hypoxia, potently induces vascular permeability, and is associated with high-altitude-induced pulmonary edema. Hantaviruses alter the normal regulation ofβ3 integrins that restrict VEGF-directed permeability and hantavirus infected endothelial cells are hyperresponsive to the permeabilizing effects of VEGF. However, the role of VEGF in acute pulmonary edema observed in HPS patients remains unclear. Here we retrospectively evaluate VEGF levels in pulmonary edema fluid (PEF), plasma, sera, and PBMCs from 31 HPS patients. VEGF was elevated in HPS patients PEF compared to controls with the highest levels observed in PEF samples from a fatal HPS case. VEGF levels were highest in PBMC samples during the first five days of hospitalization and diminished during recovery. Significantly increased PEF and PBMC VEGF levels are consistent with acute pulmonary edema observed in HPS patients and HPS disease severity. We observed substantially lower VEGF levels in a severe HPS disease survivor after extracorporeal membrane oxygenation. These findings suggest the importance of patients’ VEGF levels during HPS, support the involvement of VEGF responses in HPS pathogenesis, and suggest targeting VEGF responses as a potential therapeutic approach.

scholarly journals ACUTE PULMONARY EDEMA COMPLICATED BY RESPIRATORY FAILURE: TREATMENT WITH NON INVASIVE VENTILATION

2011 ◽  
Vol 57 (14) ◽  
pp. E1129
Author(s):  
Marco Poli ◽  
Paolo Trambaiolo ◽  
Filippo Corsi ◽  
Massimo De Luca ◽  
Marina Mustilli ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Pulmonary Edema ◽  
Acute Pulmonary Edema ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Failure Treatment ◽  
Non Invasive Ventilation

482 The pathogenesis of hypertensive acute pulmonary edema

2007 ◽  
Vol 6 (1) ◽  
pp. 105-105
Author(s):  
I VOGIATZIS ◽  
V SACHPEKIDIS ◽  
I VOGIATZIS ◽  
E KAMBITSI ◽  
V TSAGARIS ◽  
...  
Keyword(s):  
Pulmonary Edema ◽  
Acute Pulmonary Edema

Acute pulmonary edema as the initial presentation of a pheochromocytoma: case report

2013 ◽  
Author(s):  
Eduarda Resende ◽  
Maritza Sa ◽  
Margarida Ferreira ◽  
Silvestre Abreu
Keyword(s):  
Case Report ◽  
Pulmonary Edema ◽  
Initial Presentation ◽  
Acute Pulmonary Edema

Early application of non‐invasive ventilation for children with pulmonary edema after drowning

2021 ◽  
Author(s):  
Nihan Şık ◽  
Hüseyin Bahadır Şenol ◽  
Aykut Çağlar ◽  
Durgül Yılmaz ◽  
Murat Duman
Keyword(s):  
Pulmonary Edema ◽  
Invasive Ventilation ◽  
Early Application ◽  
Non Invasive ◽  
Non Invasive Ventilation

scholarly journals Non invasive ventilation and right ventricle function in cardiogenic pulmonary edema: an echocardiographic perspective to select the "right" ventilatory support

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
D Pedicino ◽  
A Angelini ◽  
G Russo ◽  
A D"aiello ◽  
E Rocco ◽  
...  
Keyword(s):  
Right Ventricle ◽  
Pulmonary Edema ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Cardiogenic Pulmonary Edema ◽  
Right Atrial ◽  
Controlled Study ◽  
Free Wall ◽  
Non Invasive ◽  
Rv Function

Abstract Funding Acknowledgements Type of funding sources: None. Background High-flow nasal cannulae oxygen therapy (HFNCOT) represents a better tolerated alternative to non-invasive pressure support ventilation (NIPSV) for acute cardiogenic pulmonary edema (ACPE) treatment. However, there are still few data on the effect of HFNCOT on cardiac function and hemodynamic. Purpose To assess and compare the effects of NIPSV and HFNCOT in ACPE setting on right ventricular (RV) systolic function and on indices of cardiac filling and output, as measured by echocardiography.  Methods  This is a cross-over controlled study, enrolling 15 consecutive patients admitted to our Cardiovascular Intensive Care Unit for ACPE and hypoxaemic, normo/hypocapnic acute respiratory failure, with P/F ratio < 200. Each patient received NIPSV, followed by HFNCOT. Full echocardiographic assessment and blood gas analysis (BGA) were performed 40 minutes from onset of each ventilation modality, respectively before NIPSV to HFNCOT switch and before HFNCOT interruption. In particular, RV function parameters, together with RV and atrial strain, were prospectively collected. Results  In spite of not significant changes in BGA, RV function was significantly improved under HFNCOT, as compared to NIPSV, as assessed by the following parameters: tricuspid annular plane excursion (TAPSE) (P = 0.001), RV S’ wave (P = 0.007), RV fractional area change (RVFAC) (P = 0.006). Strain analysis confirmed the significant improvement in RV function, with free wall global longitudinal strain (GLS) and free wall and septum GLS significantly higher under HFNCOT, as compared to NIPSV (-21% vs -18% P < 0.001, and -15% vs -19% P = 0.008, respectively,), and a significant increase in right atrial positive longitudinal strain (P < 0.001).  Conclusions NIPSV significantly affect RV function making more complex the management of patients presenting with ACPE. In this setting, HFNCOT represents a valuable alternative, providing similar respiratory outcomes while preserving good right ventricle performance.

Sign in / Sign up

Export Citation Format

Share Document