A Man With Hard Metal Lung Disease Presenting With Respiratory Failure And Bilateral Phrenic Neuropathy

2011 ◽  
Author(s):  
Luis Pena-Hernandez ◽  
Daniel Ouellette
Keyword(s):  
Respiratory Failure ◽  
Lung Disease ◽  
Hard Metal ◽  
Phrenic Neuropathy

scholarly journals Chronic respiratory disease and survival outcomes after extracorporeal membrane oxygenation

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Tak Kyu Oh ◽  
Hyoung-Won Cho ◽  
Hun-Taek Lee ◽  
In-Ae Song
Keyword(s):  
Respiratory Failure ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Disease ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease ◽  
Newly Diagnosed ◽  
Membrane Oxygenation ◽  
Obstructive Sleep ◽  
All Cause Mortality ◽  
Ecmo Therapy

Abstract Background Quality of life following extracorporeal membrane oxygenation (ECMO) therapy is an important health issue. We aimed to describe the characteristics of patients who developed chronic respiratory disease (CRD) following ECMO therapy, and investigate the association between newly diagnosed post-ECMO CRDs and 5-year all-cause mortality among ECMO survivors. Methods We analyzed data from the National Health Insurance Service in South Korea. All adult patients who underwent ECMO therapy in the intensive care unit between 2006 and 2014 were included. ECMO survivors were defined as those who survived for 365 days after ECMO therapy. Chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, lung cancer, lung disease due to external agents, obstructive sleep apnea, and lung tuberculosis were considered as CRDs. Results A total of 3055 ECMO survivors were included, and 345 (11.3%) were newly diagnosed with CRDs 365 days after ECMO therapy. The prevalence of asthma was the highest at 6.1% (185). In the multivariate logistic regression, ECMO survivors who underwent ECMO therapy for acute respiratory distress syndrome (ARDS) or respiratory failure had a 2.00-fold increase in post-ECMO CRD (95% confidence interval [CI]: 1.39 to 2.89; P < 0.001). In the multivariate Cox regression, newly diagnosed post-ECMO CRD was associated with a 1.47-fold (95% CI: 1.17 to 1.86; P = 0.001) higher 5-year all-cause mortality. Conclusions At 12 months after ECMO therapy, 11.3% of ECMO survivors were newly diagnosed with CRDs. Patients who underwent ECMO therapy for ARDS or respiratory failure were associated with a higher incidence of newly diagnosed post-ECMO CRD compared to those who underwent ECMO for other causes. Additionally, post-ECMO CRDs were associated with a higher 5-year all-cause mortality. Our results suggest that ECMO survivors with newly diagnosed post-ECMO CRD might be a high-risk group requiring dedicated interventions.

TRACE METAL LUNG DISEASE: HARD METAL PNEUMOCONIOSIS. A CASE REPORT.

2009 ◽  
Vol 59 ◽  
pp. 52-55 ◽  
Author(s):  
J. EDEL ◽  
R. PIETRA ◽  
E. SABBIONI ◽  
G. RIZZATO ◽  
M. SPEZIALI
Keyword(s):  
Case Report ◽  
Trace Metal ◽  
Lung Disease ◽  
Hard Metal

Lung Contractive Change in Severe Acute Respiratory Failure Requiring Invasive Ventilation; A Comparison of Features Between Interstitial Lung Disease and Severe Infection

2021 ◽  
Author(s):  
Kentaro Nagaoka ◽  
Yu Yamashita ◽  
Akira Oguma ◽  
Hirokazu Kimura ◽  
Kaoruko Shimizu ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Interstitial Lung Disease ◽  
Lung Injury ◽  
Acute Respiratory Failure ◽  
Lung Disease ◽  
Invasive Mechanical Ventilation ◽  
Multivariate Logistic Regression Analysis ◽  
Severe Infection ◽  
Infection Group ◽  
Radiological Features

Abstract Background: Generally, the incidence of irreversible lung injury is considered to be higher in acute respiratory failure due to interstitial lung disease (ILD), compared to those due to severe infection. However, those sub-phenotypes, which follow irreversible lung injury, remain poorly characterized. We aimed to examine their clinical and radiological features, in patients who could not withdraw from ventilation after receiving any treatment (defined as“irreversible respiratory failure”). Methods: Retrospective study including all patients receiving CT evaluation at onset and invasive mechanical ventilation for severe infection or acute ILD, who admitted our institution from April 2013 to May 2019. Participants were divided into Infection group and ILD group according to the dominant cause, and predictors of irreversible respiratory failure were examined among those subjects. In addition, we quantitatively evaluated the changes in lung region volumes and dispersion of grand glass opacity, using automated methods. Results: 31 patients were subdivided to ILD group, whereas 139 patients were subdivided to Infection group. Significantly more subjects in ILD group developed irreversible respiratory failure (n=22; 70.9%), compared to those in Infection group (n=27; 19.4%; p<0.001). With validation of radiological features in those subjects, distinct CT findings, including lung contractive change and non-edematous lung injury (NE-LI), were found in both groups. Lung contractive change was observed with 23 subjects in ILD group (74.2%) and 7 subjects in Infection group (5.0%). Among those, >10% lung volume reduction was confirmed by CT analysis with 19 subjects in ILD group and 4 subjects in Infection group. By multivariate logistic regression analysis, the following factors were found to be strong predictors of irreversible respiratory failure; lung contractive change (odds ratio [OR]=32.6; 95% confidence interval [CI], 7.1-150), NE-LI suspicious lesion (OR=13.3; 95% CI [2.9-59]), ILD-dominant respiratory failure (OR=18.4; 95% CI, 4.3-79), multidrug-resistant bacterial- or fungal-infection (OR=6.4; 95% CI, 1.3-31). Conclusions: We demonstrated the presence of sub-phenotypes in acute respiratory failure due to ILD and severe infection, which followed an irreversible course with distinctive radiological features including lung contractive changes.

Trace of Metal Exposure in Hard Metal Lung Disease

CHEST Journal ◽  
1986 ◽  
Vol 90 (1) ◽  
pp. 101-106 ◽  
Author(s):  
G. Rizzato ◽  
S. Lo Cicero ◽  
M. Barberis ◽  
M. Torre ◽  
R. Pietra ◽  
...  
Keyword(s):  
Lung Disease ◽  
Hard Metal ◽  
Metal Exposure

Hard Metal Lung Disease

2012 ◽  
pp. 217-230 ◽  
Author(s):  
Toshinori Takada ◽  
Hiroshi Moriyama
Keyword(s):  
Lung Disease ◽  
Hard Metal

scholarly journals Increased Respiratory Morbidity in Individuals with Interstitial Lung Abnormalities

2020 ◽  
Author(s):  
Nils Hoyer ◽  
Laura H. Thomsen ◽  
Mathilde M.W. Wille ◽  
Torgny Wilcke ◽  
Asger Dirksen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Respiratory Failure ◽  
Cancer Screening ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Respiratory Diseases ◽  
Lung Cancer Screening ◽  
Healthcare Utilisation ◽  
Lung Abnormalities ◽  
Disease Specific

Abstract Background Interstitial lung abnormalities (ILA) are common in participants of lung cancer screening trials and broad population-based cohorts. They are associated with increased mortality, but less is known about disease specific morbidity and healthcare utilisation in individuals with ILA. Methods We included all participants from the screening arm of the Danish Lung Cancer Screening Trial with available baseline CT scan data (n=1990) in this cohort study. The baseline scan was scored for the presence of ILA and patients were followed for up to 12 years. Data about all hospital admissions, primary healthcare visits and medicine prescriptions were collected from the Danish National Health Registries and used to determine the participants’ disease specific morbidity and healthcare utilisation using Cox proportional hazards models. Results The 332 (16.7%) participants with ILA were more likely to be diagnosed with one of several respiratory diseases, including interstitial lung disease (HR: 4.9, 95% CI: 1.8–13.3, p=0.008), COPD (HR: 1.7, 95% CI: 1.2–2.3, p = 0.01), pneumonia (HR: 2.0, 95% CI: 1.4–2.7, p<0.001), lung cancer (HR: 2.7, 95% CI: 1.8–4.0, p<0.001) and respiratory failure (HR: 1.8, 95% CI: 1.1–3.0, p=0.03) compared with participants without ILA. These findings were confirmed by increased hospital admission rates with these diagnoses and more frequent prescriptions for inhalation medicine and antibiotics in participants with ILA. Conclusions Individuals with ILA are more likely to receive a diagnosis and treatment for several respiratory diseases, including interstitial lung disease, COPD, pneumonia, lung cancer and respiratory failure during long-term follow-up.

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