scholarly journals Microscopic Polyangiitis Presenting with Cardiac Tamponade in a Patient with Severe PAH: Swan-Ganz and Intra-Pericardial Pressure-Guided Drainage

Author(s):  
S. Brahmandam ◽  
S. Brahmandam ◽  
K. El-Kersh
1989 ◽  
Vol 257 (3) ◽  
pp. H726-H733
Author(s):  
G. J. Crystal ◽  
M. R. Salem

Experiments were performed on 14 anesthetized, open-chest dogs to assess myocardial and systemic responses to cardiac tamponade alone (TAMP) and combined with arterial hypoxemia (HYP). Regional blood flow (RBF) was measured with radioactive microspheres and used to compute regional O2 supply. Myocardial oxygen and lactate extraction were determined. Myocardial oxygen consumption (MVO2) was calculated with Fick equation. An increase in pericardial pressure, sufficient to reduce mean aortic pressure (MAP) by 20%, caused proportional decreases in myocardial RBF and MVO2 but had no effect on endo-to-epi flow ratio or on myocardial lactate extraction. TAMP alone decreased RBF and O2 supply in kidney, splanchnic organs, skeletal muscle, and skin, but it had no effect in brain. HYP (arterial PO2, 35 +/- 2 mmHg) during TAMP restored MAP and caused transmurally uniform increases in myocardial RBF that were adequate to maintain MVO2 and lactate extraction. RBF increased sufficiently in brain to maintain regional O2 supply, whereas unchanged or inadequate increases in RBF in other tissues accentuated reductions in O2 supply. During combined TAMP and HYP, local vasodilator mechanisms were capable of maintaining adequate oxygen supply in myocardium and brain but not apparently in the nonvital tissues where these mechanisms were antagonized by reflex vasoconstriction.


1983 ◽  
Vol 244 (6) ◽  
pp. G604-G612 ◽  
Author(s):  
G. B. Bulkley ◽  
P. R. Kvietys ◽  
M. A. Perry ◽  
D. N. Granger

The local hemodynamic response of the innervated but vascularly isolated colon to decreased systemic perfusion induced by cardiac tamponade was studied in anesthesized dogs as a model of nonocclusive mesenteric ischemia. Increasing levels of pericardial pressure caused progressive decreases in colonic blood flow associated with substantial increases in colonic vascular resistance. These increases in local colonic resistance were proportionately larger than concurrent increases in systemic resistance. The disproportionate response of the colonic resistance vessels was not diminished by colonic (sympathetic) denervation. Reductions of blood flow to 30 ml . min-1 . 100 g-1 resulted in compensatory increases in colonic oxygen extraction such that colonic oxygen consumption remained constant (flow independent) at about 1.5 ml . min-1 . 100 g-1. At blood flows below 30 ml . min-1 . 100 g-1 colonic oxygen consumption was markedly dependent on blood flow. This fundamental relation of colonic oxygen consumption to blood flow was the same whether ischemia was induced by cardiac tamponade, partial mechanical arterial occlusion, or vasoconstrictor (norepinephrine or digoxin) infusion. Furthermore, this relationship was not altered by vasodilation with isoproterenol after the induction of ischemia by any of the above means.


Author(s):  
Andrew Hilton

Cardiac tamponade results from an increase in pericardial pressure that is sufficient to impede cardiac filling, resulting in high venous filling pressures, low cardiac output, and end-organ hypoperfusion. Most often this is due to the accumulation of a pericardial effusion though there are other possible causes. Patients usually present with features of cardiogenic shock, though some may initially be normotensive or hypertensive. Echocardiography can diagnose the presence of pericardial disease, especially pericardial effusion. Any associated haemodynamic sequelae can often be inferred by static and dynamic two-dimensional echocardiographic and Doppler measured intracardiac flow velocity abnormalities. These include atrial and ventricular wall inversion or collapse, and increased respiratory phasic flow velocities in tricuspid and mitral inflow. The concepts of transmural pressure, pericardial restraint, interventricular dependence, and cardiorespiratory interactions underpin the understanding and limitations of these echocardiographic findings. However, the impact of positive pressure ventilation remains problematic with respect to the interpretation of Doppler-derived intracardiac flow velocity variation. Echocardiography can also identify conditions that may confound the interpretation of accepted echocardiographic criteria (e.g. right ventricular hypertrophy, hypovolaemia, isolated chamber compression after cardiac surgery) and diagnose conditions that may mimic or exaggerate tamponade pathophysiology such as large compressive pleural effusion. Finally, echocardiographic criteria can aid stratification of the risk of tamponade in patients with pericardial effusion, and if necessary, guide percutaneous pericardiocentesis.


2010 ◽  
Vol 16 (2) ◽  
pp. 86-87 ◽  
Author(s):  
Primal Kaur ◽  
Aniruddha Palya ◽  
Humaira Hussain ◽  
Sanjay Dabral

CHEST Journal ◽  
2019 ◽  
Vol 156 (4) ◽  
pp. A1531-A1532
Author(s):  
Abdullah Al-abcha ◽  
Mian Iftikhar ◽  
Sherif Elkinany ◽  
Ahmad Alratroot ◽  
Heather Laird-Fick ◽  
...  

1991 ◽  
Vol 261 (4) ◽  
pp. R907-R911
Author(s):  
B. D. Hoit ◽  
M. Gabel ◽  
N. O. Fowler

The effect of prior splenectomy on the hemodynamics of cardiac tamponade was investigated in 15 closed-chest pentobarbital sodium-anesthetized dogs. Hemodynamics were compared at baseline and during staged cardiac tamponade (pericardial pressures of 5, 10, and 15 mmHg) at control (n = 15) and after splenectomy (n = 8) and sham operation (n = 7). The fall in mean arterial pressure with cardiac tamponade was significantly greater in splenectomized dogs than in either sham-operated or control dogs (P less than 0.001). Cardiac output was more depressed at the third level of cardiac tamponade in splenectomized than in sham-operated or control dogs (12.8 +/- 14.5 vs. 29.3 +/- 8.7 and 25.4 +/- 9.4 ml.min-1.kg-1, respectively; both P less than 0.05 vs. splenectomy). Hemodynamic failure, defined as an inability to maintain mean arterial pressure greater than 50 mmHg for 5 min, occurred at a lower pericardial pressure in splenectomized than in sham-operated dogs (13.1 +/- 3.8 vs. 18.1 +/- 3.5 mmHg, P less than 0.05). Hematocrit increased significantly with cardiac tamponade in controls and sham-operated but not splenectomized dogs. The percent increase in hematocrit from baseline to the third stage of cardiac tamponade was 19.6 +/- 9.8 and 22.3 +/- 5.6% in control and sham dogs, respectively. Thus the canine spleen plays an important role in cardiovascular compensation to cardiac tamponade. Parallel changes in hematocrit suggest that a part of this response is due to splenic autotransfusion.


1985 ◽  
Vol 248 (2) ◽  
pp. H198-H207 ◽  
Author(s):  
R. Shabetai ◽  
D. C. Abel ◽  
J. B. Graham ◽  
V. Bhargava ◽  
R. S. Keyes ◽  
...  

Previous studies of cardiac function in elasmobranch fishes have not included the influence of the pericardioperitoneal canal on pericardial pressure and volume and thus on cardiac function. Accordingly, we studied the function of the pericardium and pericardioperitoneal canal in sharks and rays. We found negative pericardial pressure that rose to a plateau of approximately 0 mmHg when fluid was infused into the pericardium with the canal undisturbed. However, this pericardial pressure elevation caused severe cardiac tamponade. After the canal was occluded, the pressure plateau was substituted with an exponential rise. We injected radioisotopes into the pericardial cavity and obtained scintigrams several hours later. The scans and counts of body fluids and tissues indicated absorption, disputing the suggestion that the primary function of the canal may be inadequate absorption of pericardial fluid. We conclude that the pericardioperitoneal canal maintains negative pericardial pressure, which is a prerequisite in elasmobranch fishes and may serve to regulate pericardial pressure level to optimize cardiac function in relation to changes in cardiac size.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
F Ata ◽  
A Abdelrahman ◽  
E Othman ◽  
G Abushahba

Abstract Introduction Cardiac tamponade (CT) is a clinical syndrome characterized by hemodynamic abnormalities resulting from an increase in pericardial pressure due to accumulation of fluid. Tamponade is one of the cardiac emergencies where urgent management steps are crucial and life saving. Absolute goal of treatment in Cardiac tamponade is to relieve the intra-pericardial pressure and to reverse the hemodynamic shutdown, by removal of the pericardial fluid via pericardiocentesis or surgical drainage. As much inevitable as it is, pericardiocentesis is relatively contraindicated when the effusion is associated with aortic dissection or myocardial rupture due to the potential risk of aggravating the dissection or rupture via rapid pericardial decompression and restoration of systemic arterial pressure. Case description A 44-year-Old transit passenger was admitted after she developed sudden onset of palpitations, vomiting and epigastric pain. She was in sinus tachycardia when brought to the Emergency department, within minutes’ patient went into cardiac shock with severe metabolic acidosis. She was admitted to ICU and subsequently intubated. Chest X-ray showed evidence of Pleural effusion with enlarged cardiac shadow, which prompted an urgent transthoracic echocardiogram. Echo findings were consistent with clinical cardiac tamponade with a large left pericardial mass compressing the lateral LV wall and aortic root, with a color flow from the mass toward the left coronary system. Mean while the patient was rapidly deteriorating, with and patient was not stable to undergo further imaging (CT or MRI), urgent contrast echo was done to rule out vascular connection between the mass and pericardial fluid, The Echo contrast study showed no vascular connection from the mass to the pericardial space ,however there was a connection from the mass to the left coronary system as shown in the figure, based on these findings a pericardial drainage was done successfully. These findings were confirmed by contrast CT scan after patient is stabilized. Patient gradually improved clinically, was extubated successfully, the provisional diagnosis was suspicious of pheochromocytoma,however the final diagnosis not established as the patient travelled to home country for further management. Conclusion Some times, it may become clinically challenging to effectively rule out contraindications to a procedure by the gold standard modalities, specially when a patient is collapsing on the table and the clock is ticking. In such scenarios, immediate alternate approaches resulting in safe outcomes are indispensable. Likewise, in our case of emergent cardiac tamponade and a suspicious pericardial mass in a crashing patient, Transthoracic echo with Optison proved to be life saving to rule out vascular connections between cardiac mass and coronaries or pericardial fluid, when there was no time for definitive imaging modalities due to rapid deterioration of patient’s clinical status. Abstract P242 Figure.


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