Nasal Continuous Positive Airway Pressure Facilitates Respiratory Muscle Function during Sleep in Severe Chronic Obstructive Pulmonary Disease

1991 ◽  
Vol 143 (5_pt_1) ◽  
pp. 928-935 ◽  
Author(s):  
Basil J. Petrof ◽  
R. John Kimoff ◽  
Robert D. Levy ◽  
Manuel G. Cosio ◽  
Stewart B. Gottfried
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Continuous Positive Airway Pressure ◽  
Pulmonary Disease ◽  
Muscle Function ◽  
Airway Pressure ◽  
Respiratory Muscle ◽  
Positive Airway Pressure ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Respiratory Muscle Function

Non-invasive Assessment of Respiratory Muscle Function and its Relationship to Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease

2006 ◽  
Vol 34 (3) ◽  
pp. 240-246 ◽  
Author(s):  
J Chlumský ◽  
P Filipova ◽  
M Terl
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Muscle Function ◽  
Exercise Tolerance ◽  
Respiratory Muscle ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Non Invasive ◽  
Respiratory Muscle Function ◽  
Copd Patients

Most patients with chronic obstructive pulmonary disease (COPD) have impaired respiratory muscle function. Maximal oesophageal pressure correlates closely with exercise tolerance and seems to predict the distance walked during the 6-min walk test. This study assessed the non-invasive parameters of respiratory muscle function in 41 patients with COPD to investigate their relationship to pulmonary function tests and exercise tolerance. The COPD patients, who demonstrated the full range of airway obstruction severity, had a mean forced expiratory volume in 1 s of 42.5% predicted (range, 20–79% predicted). Both the maximal inspiratory muscle strength and non-invasive tension-time index were significantly correlated with the degree of lung hyperinflation, as expressed by the ratio of residual volume to total lung capacity, and the distance walked in 6 min. We conclude that respiratory muscle function was influenced mainly by lung hyperinflation and that it had an important effect on exercise tolerance in COPD patients.

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